TRIM11

 

Full name: tripartite motif containing 11 Alias Symbol: RNF92|BIA1
Type: protein-coding gene Cytoband: 1q42.13
Entrez ID: 81559 HGNC ID: HGNC:16281 Ensembl Gene: ENSG00000154370 OMIM ID: 607868
Drug and gene relationship at DGIdb

 

Expression of TRIM11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRIM11 81559 226566_at 0.7465 0.1156
GSE26886 TRIM11 81559 226566_at 0.4586 0.0341
GSE45670 TRIM11 81559 226566_at 0.7326 0.0000
GSE53622 TRIM11 81559 92124 0.5838 0.0000
GSE53624 TRIM11 81559 92124 0.7135 0.0000
GSE63941 TRIM11 81559 226566_at -0.1970 0.6036
GSE77861 TRIM11 81559 226566_at 0.4284 0.0237
GSE97050 TRIM11 81559 A_24_P50908 0.1352 0.6110
SRP007169 TRIM11 81559 RNAseq -0.2818 0.5559
SRP008496 TRIM11 81559 RNAseq -0.5015 0.1426
SRP064894 TRIM11 81559 RNAseq 0.5139 0.0380
SRP133303 TRIM11 81559 RNAseq 0.4444 0.0304
SRP159526 TRIM11 81559 RNAseq 0.2712 0.4861
SRP193095 TRIM11 81559 RNAseq 0.2122 0.0951
SRP219564 TRIM11 81559 RNAseq 0.6864 0.1851
TCGA TRIM11 81559 RNAseq 0.1636 0.0024

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TRIM11 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TRIM11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRIM11 81559 11 0 19
GSE20123 TRIM11 81559 11 0 19
GSE43470 TRIM11 81559 7 1 35
GSE46452 TRIM11 81559 4 2 53
GSE47630 TRIM11 81559 15 0 25
GSE54993 TRIM11 81559 0 6 64
GSE54994 TRIM11 81559 17 0 36
GSE60625 TRIM11 81559 0 0 11
GSE74703 TRIM11 81559 7 1 28
GSE74704 TRIM11 81559 5 0 15
TCGA TRIM11 81559 45 2 49

Total number of gains: 122; Total number of losses: 12; Total Number of normals: 354.  

 

Somatic mutations of TRIM11:

 

Generating mutation plots.

 

Highly correlated genes for TRIM11:

 

Showing top 20/335 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRIM11TIGD50.817294303
TRIM11ZFAT0.776019303
TRIM11POLR3A0.773328303
TRIM11FABP60.758117303
TRIM11CC2D1B0.757775303
TRIM11ESRRA0.730294303
TRIM11PDCD110.724637404
TRIM11ALOX12B0.718576303
TRIM11C19orf530.71507303
TRIM11GTF3C50.712053505
TRIM11FEN10.711068404
TRIM11POLD10.708384504
TRIM11BAX0.705042403
TRIM11CPAMD80.701623303
TRIM11FUT10.698843504
TRIM11BUB1B0.695819404
TRIM11UBE2S0.692377403
TRIM11TMEM120B0.689086303
TRIM11TMEM1820.684393303
TRIM11KIF4A0.679862605

For details and further investigation, click here