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Multi-Omics Database of ESCC

 

SLC2A11

 

Full name: solute carrier family 2 member 11 Alias Symbol: GLUT11|GLUT10
Type: protein-coding gene Cytoband: 22q11.23
Entrez ID: 66035 HGNC ID: HGNC:14239 Ensembl Gene: ENSG00000133460 OMIM ID: 610367
Drug and gene relationship at DGIdb

 

Expression of SLC2A11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLC2A11 66035 1558540_s_at 0.1105 0.8517
GSE20347 SLC2A11 66035 221262_s_at -0.0685 0.4228
GSE23400 SLC2A11 66035 221262_s_at -0.0034 0.9016
GSE26886 SLC2A11 66035 232167_at -0.1501 0.1245
GSE29001 SLC2A11 66035 221262_s_at -0.0191 0.9056
GSE38129 SLC2A11 66035 221262_s_at 0.0404 0.7077
GSE45670 SLC2A11 66035 1558540_s_at -0.2084 0.2188
GSE53622 SLC2A11 66035 95585 -0.2004 0.1515
GSE53624 SLC2A11 66035 95585 -0.0920 0.2894
GSE63941 SLC2A11 66035 232167_at -0.5383 0.2524
GSE77861 SLC2A11 66035 232167_at 0.0425 0.7297
GSE97050 SLC2A11 66035 A_33_P3268652 0.3555 0.1557
SRP064894 SLC2A11 66035 RNAseq 0.5402 0.0464
SRP133303 SLC2A11 66035 RNAseq -0.0779 0.5396
SRP159526 SLC2A11 66035 RNAseq 0.6290 0.0029
SRP193095 SLC2A11 66035 RNAseq 0.1032 0.3632
SRP219564 SLC2A11 66035 RNAseq -0.2315 0.7121
TCGA SLC2A11 66035 RNAseq -0.5358 0.0022

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by SLC2A11 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SLC2A11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC2A11 66035 5 7 18
GSE20123 SLC2A11 66035 5 6 19
GSE43470 SLC2A11 66035 3 6 34
GSE46452 SLC2A11 66035 32 1 26
GSE47630 SLC2A11 66035 8 5 27
GSE54993 SLC2A11 66035 3 6 61
GSE54994 SLC2A11 66035 11 7 35
GSE60625 SLC2A11 66035 5 0 6
GSE74703 SLC2A11 66035 3 5 28
GSE74704 SLC2A11 66035 2 3 15
TCGA SLC2A11 66035 26 15 55

Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.  

 

Somatic mutations of SLC2A11:

 

Generating mutation plots.

 

Highly correlated genes for SLC2A11:

 

Showing top 20/84 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC2A11RNF2150.756412303
SLC2A11U2AF1L40.753691303
SLC2A11NAT8B0.707664303
SLC2A11GYPE0.702973404
SLC2A11ALOX150.702526303
SLC2A11ITIH30.699895303
SLC2A11ABCA70.688711303
SLC2A11PTPRCAP0.68801303
SLC2A11NTN30.686068303
SLC2A11HSF40.685808303
SLC2A11IGSF9B0.685311403
SLC2A11CHRNA20.68456303
SLC2A11SLC19A30.682256303
SLC2A11C4BPA0.679335403
SLC2A11GGTLC10.675647403
SLC2A11FBXO170.671016303
SLC2A11NTRK10.661713403
SLC2A11SCGN0.66095403
SLC2A11MPO0.65935303
SLC2A11DIO30.659227404

For details and further investigation, click here