| Full name: arylsulfatase B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q14.1 | ||
| Entrez ID: 411 | HGNC ID: HGNC:714 | Ensembl Gene: ENSG00000113273 | OMIM ID: 611542 |
| Drug and gene relationship at DGIdb | |||
Expression of ARSB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARSB | 411 | 232197_x_at | 0.1725 | 0.7360 | |
| GSE20347 | ARSB | 411 | 206129_s_at | 0.1435 | 0.0307 | |
| GSE23400 | ARSB | 411 | 206129_s_at | 0.0490 | 0.2571 | |
| GSE26886 | ARSB | 411 | 206129_s_at | 0.2080 | 0.0448 | |
| GSE29001 | ARSB | 411 | 206129_s_at | 0.2797 | 0.0505 | |
| GSE38129 | ARSB | 411 | 206129_s_at | 0.1700 | 0.0692 | |
| GSE45670 | ARSB | 411 | 232197_x_at | -0.2155 | 0.3891 | |
| GSE53622 | ARSB | 411 | 103781 | 0.5333 | 0.0000 | |
| GSE53624 | ARSB | 411 | 103781 | 0.7208 | 0.0000 | |
| GSE63941 | ARSB | 411 | 232197_x_at | -3.7323 | 0.0000 | |
| GSE77861 | ARSB | 411 | 1554030_at | -0.0934 | 0.2493 | |
| GSE97050 | ARSB | 411 | A_24_P205213 | 0.1999 | 0.5996 | |
| SRP007169 | ARSB | 411 | RNAseq | 2.3902 | 0.0000 | |
| SRP008496 | ARSB | 411 | RNAseq | 2.6178 | 0.0000 | |
| SRP064894 | ARSB | 411 | RNAseq | 1.2196 | 0.0000 | |
| SRP133303 | ARSB | 411 | RNAseq | 0.8986 | 0.0003 | |
| SRP159526 | ARSB | 411 | RNAseq | 1.0387 | 0.0010 | |
| SRP193095 | ARSB | 411 | RNAseq | 0.9944 | 0.0000 | |
| SRP219564 | ARSB | 411 | RNAseq | 0.8022 | 0.3194 | |
| TCGA | ARSB | 411 | RNAseq | -0.1638 | 0.0833 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by ARSB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARSB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARSB | 411 | 1 | 13 | 16 | |
| GSE20123 | ARSB | 411 | 1 | 13 | 16 | |
| GSE43470 | ARSB | 411 | 1 | 13 | 29 | |
| GSE46452 | ARSB | 411 | 0 | 28 | 31 | |
| GSE47630 | ARSB | 411 | 1 | 19 | 20 | |
| GSE54993 | ARSB | 411 | 8 | 1 | 61 | |
| GSE54994 | ARSB | 411 | 1 | 19 | 33 | |
| GSE60625 | ARSB | 411 | 0 | 0 | 11 | |
| GSE74703 | ARSB | 411 | 1 | 9 | 26 | |
| GSE74704 | ARSB | 411 | 1 | 6 | 13 | |
| TCGA | ARSB | 411 | 4 | 50 | 42 |
Total number of gains: 19; Total number of losses: 171; Total Number of normals: 298.
Somatic mutations of ARSB:
Generating mutation plots.
Highly correlated genes for ARSB:
Showing top 20/642 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARSB | SGTB | 0.810653 | 4 | 0 | 4 |
| ARSB | CHL1 | 0.737495 | 3 | 0 | 3 |
| ARSB | RAB34 | 0.717978 | 3 | 0 | 3 |
| ARSB | FKBP7 | 0.711917 | 7 | 0 | 6 |
| ARSB | S1PR1 | 0.707301 | 4 | 0 | 3 |
| ARSB | PCDH18 | 0.706678 | 5 | 0 | 5 |
| ARSB | SUSD1 | 0.70462 | 3 | 0 | 3 |
| ARSB | C11orf96 | 0.700124 | 4 | 0 | 3 |
| ARSB | TNFRSF10D | 0.698051 | 3 | 0 | 3 |
| ARSB | ZNF578 | 0.69729 | 3 | 0 | 3 |
| ARSB | FADS1 | 0.696849 | 3 | 0 | 3 |
| ARSB | UHRF1BP1L | 0.693537 | 4 | 0 | 4 |
| ARSB | WDR7 | 0.691741 | 3 | 0 | 3 |
| ARSB | CLMP | 0.688381 | 6 | 0 | 5 |
| ARSB | SLC39A13 | 0.679394 | 6 | 0 | 4 |
| ARSB | RBPJ | 0.679389 | 4 | 0 | 4 |
| ARSB | SEC23A | 0.678711 | 6 | 0 | 5 |
| ARSB | SYNE1 | 0.676722 | 4 | 0 | 3 |
| ARSB | UXS1 | 0.67634 | 3 | 0 | 3 |
| ARSB | ZNF322 | 0.676064 | 3 | 0 | 3 |
For details and further investigation, click here
