| Full name: WD repeat domain 7 | Alias Symbol: KIAA0541|TRAG | ||
| Type: protein-coding gene | Cytoband: 18q21.31 | ||
| Entrez ID: 23335 | HGNC ID: HGNC:13490 | Ensembl Gene: ENSG00000091157 | OMIM ID: 613473 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of WDR7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR7 | 23335 | 212880_at | -0.0013 | 0.9988 | |
| GSE20347 | WDR7 | 23335 | 212880_at | -0.3669 | 0.0164 | |
| GSE23400 | WDR7 | 23335 | 212880_at | -0.0712 | 0.3053 | |
| GSE26886 | WDR7 | 23335 | 212880_at | -0.8281 | 0.0028 | |
| GSE29001 | WDR7 | 23335 | 212880_at | -0.2577 | 0.0718 | |
| GSE38129 | WDR7 | 23335 | 212880_at | -0.4111 | 0.0021 | |
| GSE45670 | WDR7 | 23335 | 212880_at | -0.3664 | 0.0188 | |
| GSE53622 | WDR7 | 23335 | 76234 | -0.2134 | 0.0003 | |
| GSE53624 | WDR7 | 23335 | 47160 | -0.4765 | 0.0000 | |
| GSE63941 | WDR7 | 23335 | 212880_at | -1.9018 | 0.0024 | |
| GSE77861 | WDR7 | 23335 | 212880_at | 0.0018 | 0.9972 | |
| GSE97050 | WDR7 | 23335 | A_23_P164528 | -0.0909 | 0.6719 | |
| SRP007169 | WDR7 | 23335 | RNAseq | 0.5722 | 0.2740 | |
| SRP008496 | WDR7 | 23335 | RNAseq | 0.5215 | 0.0950 | |
| SRP064894 | WDR7 | 23335 | RNAseq | -0.0424 | 0.8528 | |
| SRP133303 | WDR7 | 23335 | RNAseq | -0.1654 | 0.2052 | |
| SRP159526 | WDR7 | 23335 | RNAseq | -0.1175 | 0.7460 | |
| SRP193095 | WDR7 | 23335 | RNAseq | -0.1206 | 0.2456 | |
| SRP219564 | WDR7 | 23335 | RNAseq | -0.0088 | 0.9870 | |
| TCGA | WDR7 | 23335 | RNAseq | -0.2168 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by WDR7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR7 | 23335 | 2 | 9 | 19 | |
| GSE20123 | WDR7 | 23335 | 2 | 9 | 19 | |
| GSE43470 | WDR7 | 23335 | 0 | 5 | 38 | |
| GSE46452 | WDR7 | 23335 | 1 | 26 | 32 | |
| GSE47630 | WDR7 | 23335 | 5 | 20 | 15 | |
| GSE54993 | WDR7 | 23335 | 10 | 0 | 60 | |
| GSE54994 | WDR7 | 23335 | 1 | 20 | 32 | |
| GSE60625 | WDR7 | 23335 | 0 | 4 | 7 | |
| GSE74703 | WDR7 | 23335 | 0 | 5 | 31 | |
| GSE74704 | WDR7 | 23335 | 2 | 6 | 12 | |
| TCGA | WDR7 | 23335 | 8 | 44 | 44 |
Total number of gains: 31; Total number of losses: 148; Total Number of normals: 309.
Somatic mutations of WDR7:
Generating mutation plots.
Highly correlated genes for WDR7:
Showing top 20/794 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR7 | PPID | 0.77004 | 3 | 0 | 3 |
| WDR7 | CPEB4 | 0.716985 | 3 | 0 | 3 |
| WDR7 | HDHD2 | 0.716808 | 5 | 0 | 5 |
| WDR7 | ATXN7L3B | 0.709475 | 3 | 0 | 3 |
| WDR7 | SLC12A6 | 0.698587 | 3 | 0 | 3 |
| WDR7 | PTPRA | 0.695488 | 4 | 0 | 3 |
| WDR7 | ASH2L | 0.695235 | 3 | 0 | 3 |
| WDR7 | PEX2 | 0.692577 | 4 | 0 | 3 |
| WDR7 | HIPK2 | 0.691919 | 3 | 0 | 3 |
| WDR7 | ARSB | 0.691741 | 3 | 0 | 3 |
| WDR7 | RNF125 | 0.688346 | 4 | 0 | 4 |
| WDR7 | CNOT4 | 0.687416 | 3 | 0 | 3 |
| WDR7 | HAUS1 | 0.686168 | 3 | 0 | 3 |
| WDR7 | ITCH | 0.684121 | 3 | 0 | 3 |
| WDR7 | KIAA2026 | 0.682783 | 4 | 0 | 3 |
| WDR7 | NIPAL3 | 0.681407 | 4 | 0 | 4 |
| WDR7 | TMX3 | 0.678445 | 6 | 0 | 4 |
| WDR7 | ZMPSTE24 | 0.678089 | 3 | 0 | 3 |
| WDR7 | SNX25 | 0.677665 | 3 | 0 | 3 |
| WDR7 | ZRANB1 | 0.674735 | 3 | 0 | 3 |
For details and further investigation, click here
