| Full name: cell adhesion molecule L1 like | Alias Symbol: CALL|L1CAM2|FLJ44930|MGC132578 | ||
| Type: protein-coding gene | Cytoband: 3p26.3 | ||
| Entrez ID: 10752 | HGNC ID: HGNC:1939 | Ensembl Gene: ENSG00000134121 | OMIM ID: 607416 |
| Drug and gene relationship at DGIdb | |||
Expression of CHL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHL1 | 10752 | 204591_at | -0.9385 | 0.4534 | |
| GSE20347 | CHL1 | 10752 | 204591_at | -0.5587 | 0.3418 | |
| GSE23400 | CHL1 | 10752 | 204591_at | -0.2193 | 0.2139 | |
| GSE26886 | CHL1 | 10752 | 204591_at | -2.9223 | 0.0000 | |
| GSE29001 | CHL1 | 10752 | 204591_at | -1.5547 | 0.0435 | |
| GSE38129 | CHL1 | 10752 | 204591_at | -1.0063 | 0.0158 | |
| GSE45670 | CHL1 | 10752 | 204591_at | 0.2690 | 0.7086 | |
| GSE53622 | CHL1 | 10752 | 24501 | -1.2695 | 0.0000 | |
| GSE53624 | CHL1 | 10752 | 24501 | -1.7235 | 0.0000 | |
| GSE63941 | CHL1 | 10752 | 204591_at | -5.7449 | 0.0000 | |
| GSE77861 | CHL1 | 10752 | 204591_at | -0.3263 | 0.3251 | |
| GSE97050 | CHL1 | 10752 | A_23_P212241 | -0.6568 | 0.2460 | |
| SRP007169 | CHL1 | 10752 | RNAseq | -0.0589 | 0.9556 | |
| SRP008496 | CHL1 | 10752 | RNAseq | -0.3854 | 0.6868 | |
| SRP064894 | CHL1 | 10752 | RNAseq | 1.3052 | 0.0228 | |
| SRP133303 | CHL1 | 10752 | RNAseq | 0.1532 | 0.7825 | |
| SRP159526 | CHL1 | 10752 | RNAseq | -0.0512 | 0.9539 | |
| SRP193095 | CHL1 | 10752 | RNAseq | -0.7067 | 0.0489 | |
| SRP219564 | CHL1 | 10752 | RNAseq | -0.7526 | 0.4095 | |
| TCGA | CHL1 | 10752 | RNAseq | -0.2705 | 0.3981 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by CHL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHL1 | 10752 | 2 | 18 | 10 | |
| GSE20123 | CHL1 | 10752 | 2 | 18 | 10 | |
| GSE43470 | CHL1 | 10752 | 1 | 21 | 21 | |
| GSE46452 | CHL1 | 10752 | 2 | 18 | 39 | |
| GSE47630 | CHL1 | 10752 | 1 | 24 | 15 | |
| GSE54993 | CHL1 | 10752 | 7 | 1 | 62 | |
| GSE54994 | CHL1 | 10752 | 2 | 32 | 19 | |
| GSE60625 | CHL1 | 10752 | 2 | 3 | 6 | |
| GSE74703 | CHL1 | 10752 | 1 | 18 | 17 | |
| GSE74704 | CHL1 | 10752 | 1 | 12 | 7 | |
| TCGA | CHL1 | 10752 | 4 | 65 | 27 |
Total number of gains: 25; Total number of losses: 230; Total Number of normals: 233.
Somatic mutations of CHL1:
Generating mutation plots.
Highly correlated genes for CHL1:
Showing top 20/451 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHL1 | ROCK2 | 0.79853 | 3 | 0 | 3 |
| CHL1 | EIF4G3 | 0.782492 | 3 | 0 | 3 |
| CHL1 | TMEM98 | 0.76321 | 3 | 0 | 3 |
| CHL1 | MSL3 | 0.742817 | 3 | 0 | 3 |
| CHL1 | ARSB | 0.737495 | 3 | 0 | 3 |
| CHL1 | IRAK1BP1 | 0.732464 | 3 | 0 | 3 |
| CHL1 | PELO | 0.725554 | 3 | 0 | 3 |
| CHL1 | PDCD7 | 0.72087 | 3 | 0 | 3 |
| CHL1 | LYRM7 | 0.713312 | 3 | 0 | 3 |
| CHL1 | MAP4K3 | 0.712407 | 3 | 0 | 3 |
| CHL1 | LPIN2 | 0.705835 | 3 | 0 | 3 |
| CHL1 | TRIM23 | 0.704929 | 3 | 0 | 3 |
| CHL1 | TRIP12 | 0.704432 | 3 | 0 | 3 |
| CHL1 | SNX18 | 0.701229 | 3 | 0 | 3 |
| CHL1 | KLHL18 | 0.697992 | 3 | 0 | 3 |
| CHL1 | BMP4 | 0.696141 | 4 | 0 | 4 |
| CHL1 | PEAK1 | 0.695528 | 3 | 0 | 3 |
| CHL1 | DNAJB9 | 0.694705 | 3 | 0 | 3 |
| CHL1 | FAM13C | 0.69208 | 4 | 0 | 4 |
| CHL1 | DOCK1 | 0.691835 | 3 | 0 | 3 |
For details and further investigation, click here
