TNFRSF10D

 

Full name: TNF receptor superfamily member 10d Alias Symbol: DcR2|TRUNDD|TRAILR4|CD264
Type: protein-coding gene Cytoband: 8p21.3
Entrez ID: 8793 HGNC ID: HGNC:11907 Ensembl Gene: ENSG00000173530 OMIM ID: 603614
Drug and gene relationship at DGIdb

 

TNFRSF10D involved pathways:

KEGG pathway Description View
hsa04210Apoptosis
hsa04650Natural killer cell mediated cytotoxicity
hsa05162Measles

 

Expression of TNFRSF10D:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TNFRSF10D 8793 227345_at 0.5041 0.4970
GSE20347 TNFRSF10D 8793 210654_at 0.0666 0.2167
GSE23400 TNFRSF10D 8793 210654_at -0.0080 0.7795
GSE26886 TNFRSF10D 8793 227345_at 0.7354 0.0977
GSE29001 TNFRSF10D 8793 210654_at 0.0295 0.8484
GSE38129 TNFRSF10D 8793 210654_at 0.0295 0.6353
GSE45670 TNFRSF10D 8793 227345_at 0.5074 0.1927
GSE53622 TNFRSF10D 8793 12276 0.4102 0.0493
GSE53624 TNFRSF10D 8793 12276 0.5936 0.0001
GSE63941 TNFRSF10D 8793 227345_at -2.9020 0.0450
GSE77861 TNFRSF10D 8793 227345_at 0.8779 0.2690
GSE97050 TNFRSF10D 8793 A_33_P3326588 0.2353 0.6631
SRP007169 TNFRSF10D 8793 RNAseq 0.7505 0.2511
SRP064894 TNFRSF10D 8793 RNAseq 0.4667 0.1152
SRP133303 TNFRSF10D 8793 RNAseq 0.6217 0.0288
SRP159526 TNFRSF10D 8793 RNAseq 0.4675 0.3948
SRP193095 TNFRSF10D 8793 RNAseq 1.2822 0.0000
SRP219564 TNFRSF10D 8793 RNAseq -0.9073 0.1850
TCGA TNFRSF10D 8793 RNAseq -0.4119 0.0318

Upregulated datasets: 1; Downregulated datasets: 1.  

 

Survival by TNFRSF10D expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TNFRSF10D:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TNFRSF10D 8793 4 12 14
GSE20123 TNFRSF10D 8793 4 12 14
GSE43470 TNFRSF10D 8793 4 9 30
GSE46452 TNFRSF10D 8793 13 13 33
GSE47630 TNFRSF10D 8793 10 8 22
GSE54993 TNFRSF10D 8793 2 14 54
GSE54994 TNFRSF10D 8793 8 18 27
GSE60625 TNFRSF10D 8793 3 0 8
GSE74703 TNFRSF10D 8793 4 7 25
GSE74704 TNFRSF10D 8793 3 8 9
TCGA TNFRSF10D 8793 14 43 39

Total number of gains: 69; Total number of losses: 144; Total Number of normals: 275.  

 

Somatic mutations of TNFRSF10D:

 

Generating mutation plots.

 

Highly correlated genes for TNFRSF10D:

 

Showing top 20/510 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TNFRSF10DLRRC340.766922303
TNFRSF10DLCAT0.762364303
TNFRSF10DHMCN10.762088404
TNFRSF10DDCHS10.742333303
TNFRSF10DTNFRSF190.740761303
TNFRSF10DMRGPRF0.738954303
TNFRSF10DFGF10.734492303
TNFRSF10DMAN1A10.732446403
TNFRSF10DSPRY4-IT10.730027404
TNFRSF10DSTK17A0.72828403
TNFRSF10DGNL3L0.726411303
TNFRSF10DFZD10.725761303
TNFRSF10DPCSK10.725646303
TNFRSF10DKANK40.71975403
TNFRSF10DMAGEH10.709517303
TNFRSF10DPSMC10.708141403
TNFRSF10DPPP1R210.705496303
TNFRSF10DSTX160.703519303
TNFRSF10DSPATA90.69955303
TNFRSF10DRPS27L0.698536303

For details and further investigation, click here