| Full name: Sec23 homolog A, coat complex II component | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q21.1 | ||
| Entrez ID: 10484 | HGNC ID: HGNC:10701 | Ensembl Gene: ENSG00000100934 | OMIM ID: 610511 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC23A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC23A | 10484 | 212887_at | 0.1111 | 0.9245 | |
| GSE20347 | SEC23A | 10484 | 212887_at | 0.6544 | 0.0533 | |
| GSE23400 | SEC23A | 10484 | 212887_at | 0.6647 | 0.0001 | |
| GSE26886 | SEC23A | 10484 | 212887_at | 0.4555 | 0.1154 | |
| GSE29001 | SEC23A | 10484 | 212887_at | 0.7723 | 0.0328 | |
| GSE38129 | SEC23A | 10484 | 212887_at | 0.2399 | 0.3666 | |
| GSE45670 | SEC23A | 10484 | 212887_at | -0.0124 | 0.9659 | |
| GSE53622 | SEC23A | 10484 | 130475 | 0.6028 | 0.0000 | |
| GSE53624 | SEC23A | 10484 | 130475 | 0.6046 | 0.0000 | |
| GSE63941 | SEC23A | 10484 | 212887_at | -1.8667 | 0.0027 | |
| GSE77861 | SEC23A | 10484 | 212887_at | 0.6535 | 0.2533 | |
| GSE97050 | SEC23A | 10484 | A_23_P140170 | 0.1567 | 0.6589 | |
| SRP007169 | SEC23A | 10484 | RNAseq | 1.1471 | 0.0055 | |
| SRP008496 | SEC23A | 10484 | RNAseq | 1.1963 | 0.0000 | |
| SRP064894 | SEC23A | 10484 | RNAseq | 0.7635 | 0.0037 | |
| SRP133303 | SEC23A | 10484 | RNAseq | 1.5993 | 0.0010 | |
| SRP159526 | SEC23A | 10484 | RNAseq | -0.3243 | 0.2708 | |
| SRP193095 | SEC23A | 10484 | RNAseq | 0.4187 | 0.0393 | |
| SRP219564 | SEC23A | 10484 | RNAseq | 0.1527 | 0.7994 | |
| TCGA | SEC23A | 10484 | RNAseq | 0.0698 | 0.2463 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by SEC23A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC23A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC23A | 10484 | 9 | 5 | 16 | |
| GSE20123 | SEC23A | 10484 | 9 | 5 | 16 | |
| GSE43470 | SEC23A | 10484 | 9 | 3 | 31 | |
| GSE46452 | SEC23A | 10484 | 18 | 2 | 39 | |
| GSE47630 | SEC23A | 10484 | 11 | 10 | 19 | |
| GSE54993 | SEC23A | 10484 | 3 | 9 | 58 | |
| GSE54994 | SEC23A | 10484 | 19 | 5 | 29 | |
| GSE60625 | SEC23A | 10484 | 0 | 2 | 9 | |
| GSE74703 | SEC23A | 10484 | 8 | 3 | 25 | |
| GSE74704 | SEC23A | 10484 | 4 | 3 | 13 | |
| TCGA | SEC23A | 10484 | 36 | 12 | 48 |
Total number of gains: 126; Total number of losses: 59; Total Number of normals: 303.
Somatic mutations of SEC23A:
Generating mutation plots.
Highly correlated genes for SEC23A:
Showing top 20/939 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC23A | PPP1R21 | 0.79923 | 3 | 0 | 3 |
| SEC23A | ANGPTL4 | 0.755104 | 3 | 0 | 3 |
| SEC23A | NAPG | 0.753148 | 3 | 0 | 3 |
| SEC23A | BCL6 | 0.738339 | 3 | 0 | 3 |
| SEC23A | C20orf194 | 0.72912 | 3 | 0 | 3 |
| SEC23A | RTF1 | 0.707972 | 3 | 0 | 3 |
| SEC23A | KIF2A | 0.703321 | 3 | 0 | 3 |
| SEC23A | HIBADH | 0.702096 | 3 | 0 | 3 |
| SEC23A | STARD3NL | 0.701028 | 5 | 0 | 5 |
| SEC23A | FARS2 | 0.699862 | 3 | 0 | 3 |
| SEC23A | STRN3 | 0.698921 | 11 | 0 | 10 |
| SEC23A | C9orf47 | 0.693175 | 3 | 0 | 3 |
| SEC23A | FCGR3A | 0.69199 | 3 | 0 | 3 |
| SEC23A | TGFBR1 | 0.690983 | 6 | 0 | 6 |
| SEC23A | RAB11FIP5 | 0.684979 | 4 | 0 | 4 |
| SEC23A | CDAN1 | 0.683881 | 3 | 0 | 3 |
| SEC23A | SLC15A4 | 0.683147 | 6 | 0 | 6 |
| SEC23A | MAPK1IP1L | 0.681825 | 5 | 0 | 5 |
| SEC23A | POLR2L | 0.680093 | 3 | 0 | 3 |
| SEC23A | ARSB | 0.678711 | 6 | 0 | 5 |
For details and further investigation, click here
