| Full name: zinc finger protein 578 | Alias Symbol: FLJ31384 | ||
| Type: protein-coding gene | Cytoband: 19q13.41 | ||
| Entrez ID: 147660 | HGNC ID: HGNC:26449 | Ensembl Gene: ENSG00000258405 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF578:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF578 | 147660 | 1562244_at | 0.6680 | 0.6397 | |
| GSE26886 | ZNF578 | 147660 | 1562244_at | -0.0386 | 0.6977 | |
| GSE45670 | ZNF578 | 147660 | 1562244_at | -0.1503 | 0.1045 | |
| GSE63941 | ZNF578 | 147660 | 1562244_at | -2.1581 | 0.0007 | |
| GSE77861 | ZNF578 | 147660 | 1562244_at | -0.1243 | 0.2456 | |
| GSE97050 | ZNF578 | 147660 | A_33_P3345132 | -0.2657 | 0.4609 | |
| SRP007169 | ZNF578 | 147660 | RNAseq | -0.1770 | 0.7156 | |
| SRP064894 | ZNF578 | 147660 | RNAseq | 0.1377 | 0.5797 | |
| SRP133303 | ZNF578 | 147660 | RNAseq | -0.0552 | 0.7781 | |
| SRP159526 | ZNF578 | 147660 | RNAseq | -0.5382 | 0.2826 | |
| SRP193095 | ZNF578 | 147660 | RNAseq | -0.0784 | 0.5921 | |
| SRP219564 | ZNF578 | 147660 | RNAseq | 0.2717 | 0.4764 | |
| TCGA | ZNF578 | 147660 | RNAseq | -1.0229 | 0.0046 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ZNF578 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZNF578:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF578 | 147660 | 3 | 5 | 22 | |
| GSE20123 | ZNF578 | 147660 | 3 | 4 | 23 | |
| GSE43470 | ZNF578 | 147660 | 2 | 11 | 30 | |
| GSE46452 | ZNF578 | 147660 | 45 | 1 | 13 | |
| GSE47630 | ZNF578 | 147660 | 9 | 6 | 25 | |
| GSE54993 | ZNF578 | 147660 | 17 | 4 | 49 | |
| GSE54994 | ZNF578 | 147660 | 4 | 14 | 35 | |
| GSE60625 | ZNF578 | 147660 | 9 | 0 | 2 | |
| GSE74703 | ZNF578 | 147660 | 2 | 7 | 27 | |
| GSE74704 | ZNF578 | 147660 | 3 | 2 | 15 | |
| TCGA | ZNF578 | 147660 | 15 | 20 | 61 |
Total number of gains: 112; Total number of losses: 74; Total Number of normals: 302.
Somatic mutations of ZNF578:
Generating mutation plots.
Highly correlated genes for ZNF578:
Showing top 20/175 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF578 | C16orf46 | 0.83619 | 3 | 0 | 3 |
| ZNF578 | GYG2 | 0.827876 | 3 | 0 | 3 |
| ZNF578 | IP6K1 | 0.823752 | 3 | 0 | 3 |
| ZNF578 | SON | 0.815788 | 3 | 0 | 3 |
| ZNF578 | PDE5A | 0.813858 | 3 | 0 | 3 |
| ZNF578 | ZNF322 | 0.80978 | 3 | 0 | 3 |
| ZNF578 | SCAF8 | 0.80899 | 3 | 0 | 3 |
| ZNF578 | ZNF506 | 0.803494 | 3 | 0 | 3 |
| ZNF578 | RABEP2 | 0.795021 | 4 | 0 | 4 |
| ZNF578 | CASP9 | 0.794519 | 3 | 0 | 3 |
| ZNF578 | RRAGB | 0.791067 | 3 | 0 | 3 |
| ZNF578 | TSPAN5 | 0.787074 | 3 | 0 | 3 |
| ZNF578 | ZNF347 | 0.786155 | 3 | 0 | 3 |
| ZNF578 | APBB1IP | 0.784383 | 3 | 0 | 3 |
| ZNF578 | ZBTB2 | 0.780409 | 3 | 0 | 3 |
| ZNF578 | ZNF518A | 0.776335 | 3 | 0 | 3 |
| ZNF578 | OTUD7B | 0.775255 | 3 | 0 | 3 |
| ZNF578 | CCNB3 | 0.771014 | 3 | 0 | 3 |
| ZNF578 | LRRC34 | 0.770656 | 3 | 0 | 3 |
| ZNF578 | BET1 | 0.76985 | 3 | 0 | 3 |
For details and further investigation, click here
