| Full name: ankyrin repeat and SOCS box containing 4 | Alias Symbol: ASB-4 | ||
| Type: protein-coding gene | Cytoband: 7q21.3 | ||
| Entrez ID: 51666 | HGNC ID: HGNC:16009 | Ensembl Gene: ENSG00000005981 | OMIM ID: 605761 |
| Drug and gene relationship at DGIdb | |||
Expression of ASB4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASB4 | 51666 | 235619_at | 0.1547 | 0.4456 | |
| GSE20347 | ASB4 | 51666 | 208481_at | -0.0004 | 0.9968 | |
| GSE23400 | ASB4 | 51666 | 217228_s_at | -0.0486 | 0.0366 | |
| GSE26886 | ASB4 | 51666 | 235619_at | 0.6579 | 0.0499 | |
| GSE29001 | ASB4 | 51666 | 208481_at | 0.0068 | 0.9688 | |
| GSE38129 | ASB4 | 51666 | 208481_at | -0.0311 | 0.6116 | |
| GSE45670 | ASB4 | 51666 | 235619_at | 0.3037 | 0.6023 | |
| GSE53622 | ASB4 | 51666 | 67548 | 0.1830 | 0.2276 | |
| GSE53624 | ASB4 | 51666 | 67548 | 0.1136 | 0.1872 | |
| GSE63941 | ASB4 | 51666 | 235619_at | 0.0947 | 0.5838 | |
| GSE77861 | ASB4 | 51666 | 235619_at | 0.0544 | 0.5780 | |
| SRP133303 | ASB4 | 51666 | RNAseq | 0.4126 | 0.0187 | |
| SRP159526 | ASB4 | 51666 | RNAseq | 0.1984 | 0.6224 | |
| SRP193095 | ASB4 | 51666 | RNAseq | 0.3577 | 0.0091 | |
| SRP219564 | ASB4 | 51666 | RNAseq | 0.4257 | 0.3606 | |
| TCGA | ASB4 | 51666 | RNAseq | 0.8917 | 0.3676 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ASB4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASB4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASB4 | 51666 | 13 | 0 | 17 | |
| GSE20123 | ASB4 | 51666 | 13 | 0 | 17 | |
| GSE43470 | ASB4 | 51666 | 8 | 1 | 34 | |
| GSE46452 | ASB4 | 51666 | 12 | 0 | 47 | |
| GSE47630 | ASB4 | 51666 | 8 | 2 | 30 | |
| GSE54993 | ASB4 | 51666 | 1 | 9 | 60 | |
| GSE54994 | ASB4 | 51666 | 16 | 3 | 34 | |
| GSE60625 | ASB4 | 51666 | 0 | 5 | 6 | |
| GSE74703 | ASB4 | 51666 | 7 | 1 | 28 | |
| GSE74704 | ASB4 | 51666 | 9 | 0 | 11 | |
| TCGA | ASB4 | 51666 | 56 | 4 | 36 |
Total number of gains: 143; Total number of losses: 25; Total Number of normals: 320.
Somatic mutations of ASB4:
Generating mutation plots.
Highly correlated genes for ASB4:
Showing top 20/320 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASB4 | HAP1 | 0.695305 | 3 | 0 | 3 |
| ASB4 | LINC01361 | 0.695091 | 3 | 0 | 3 |
| ASB4 | ELSPBP1 | 0.688818 | 4 | 0 | 4 |
| ASB4 | CHST4 | 0.688677 | 4 | 0 | 3 |
| ASB4 | CNGB1 | 0.68242 | 3 | 0 | 3 |
| ASB4 | RNF165 | 0.677846 | 3 | 0 | 3 |
| ASB4 | CCDC144A | 0.673056 | 3 | 0 | 3 |
| ASB4 | GDF5 | 0.667889 | 5 | 0 | 4 |
| ASB4 | OR1A1 | 0.66666 | 4 | 0 | 4 |
| ASB4 | NEURL1 | 0.665769 | 3 | 0 | 3 |
| ASB4 | GABRB2 | 0.660381 | 4 | 0 | 3 |
| ASB4 | TCP10L | 0.654443 | 4 | 0 | 3 |
| ASB4 | KIR2DL2 | 0.648259 | 4 | 0 | 4 |
| ASB4 | AKAP5 | 0.644368 | 5 | 0 | 4 |
| ASB4 | CPLX1 | 0.643714 | 3 | 0 | 3 |
| ASB4 | CHRM5 | 0.643443 | 4 | 0 | 3 |
| ASB4 | FOXN3-AS2 | 0.642999 | 4 | 0 | 4 |
| ASB4 | PNMA3 | 0.642384 | 6 | 0 | 5 |
| ASB4 | OPRM1 | 0.640494 | 4 | 0 | 3 |
| ASB4 | SSTR3 | 0.64031 | 3 | 0 | 3 |
For details and further investigation, click here
