| Full name: olfactory receptor family 1 subfamily A member 1 | Alias Symbol: OR17-7 | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 8383 | HGNC ID: HGNC:8179 | Ensembl Gene: ENSG00000172146 | OMIM ID: 618046 |
| Drug and gene relationship at DGIdb | |||
OR1A1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR1A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OR1A1 | 8383 | 221388_at | -0.0576 | 0.7882 | |
| GSE20347 | OR1A1 | 8383 | 221388_at | 0.0554 | 0.5077 | |
| GSE23400 | OR1A1 | 8383 | 221388_at | -0.0372 | 0.5374 | |
| GSE26886 | OR1A1 | 8383 | 221388_at | 0.0480 | 0.7434 | |
| GSE29001 | OR1A1 | 8383 | 221388_at | -0.3338 | 0.0578 | |
| GSE38129 | OR1A1 | 8383 | 221388_at | -0.0173 | 0.8654 | |
| GSE45670 | OR1A1 | 8383 | 221388_at | -0.0195 | 0.8583 | |
| GSE63941 | OR1A1 | 8383 | 221388_at | 0.2628 | 0.1162 | |
| GSE77861 | OR1A1 | 8383 | 221388_at | 0.0677 | 0.6378 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR1A1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of OR1A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR1A1 | 8383 | 5 | 2 | 23 | |
| GSE20123 | OR1A1 | 8383 | 5 | 3 | 22 | |
| GSE43470 | OR1A1 | 8383 | 1 | 6 | 36 | |
| GSE46452 | OR1A1 | 8383 | 34 | 1 | 24 | |
| GSE47630 | OR1A1 | 8383 | 7 | 1 | 32 | |
| GSE54993 | OR1A1 | 8383 | 4 | 3 | 63 | |
| GSE54994 | OR1A1 | 8383 | 5 | 9 | 39 | |
| GSE60625 | OR1A1 | 8383 | 4 | 0 | 7 | |
| GSE74703 | OR1A1 | 8383 | 1 | 3 | 32 | |
| GSE74704 | OR1A1 | 8383 | 3 | 1 | 16 | |
| TCGA | OR1A1 | 8383 | 16 | 21 | 59 |
Total number of gains: 85; Total number of losses: 50; Total Number of normals: 353.
Somatic mutations of OR1A1:
Generating mutation plots.
Highly correlated genes for OR1A1:
Showing top 20/651 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR1A1 | KCNS1 | 0.733767 | 5 | 0 | 5 |
| OR1A1 | CYP3A4 | 0.719747 | 3 | 0 | 3 |
| OR1A1 | NPFFR1 | 0.717483 | 4 | 0 | 4 |
| OR1A1 | TCP10 | 0.715379 | 5 | 0 | 5 |
| OR1A1 | STAT2 | 0.71139 | 3 | 0 | 3 |
| OR1A1 | ATF7 | 0.706472 | 4 | 0 | 4 |
| OR1A1 | SLC45A2 | 0.69944 | 3 | 0 | 3 |
| OR1A1 | CCDC33 | 0.699274 | 3 | 0 | 3 |
| OR1A1 | GAD2 | 0.698554 | 4 | 0 | 4 |
| OR1A1 | OR10H3 | 0.696765 | 5 | 0 | 5 |
| OR1A1 | PDE1B | 0.689535 | 4 | 0 | 4 |
| OR1A1 | PRL | 0.684082 | 4 | 0 | 4 |
| OR1A1 | KRT76 | 0.68388 | 5 | 0 | 4 |
| OR1A1 | OR12D2 | 0.683149 | 4 | 0 | 3 |
| OR1A1 | KCNA2 | 0.680964 | 5 | 0 | 5 |
| OR1A1 | LUZP4 | 0.679728 | 6 | 0 | 6 |
| OR1A1 | USP49 | 0.678812 | 3 | 0 | 3 |
| OR1A1 | IL1RAPL2 | 0.677336 | 6 | 0 | 6 |
| OR1A1 | ACR | 0.676931 | 4 | 0 | 4 |
| OR1A1 | PDE3B | 0.676874 | 4 | 0 | 3 |
For details and further investigation, click here
