| Full name: somatostatin receptor 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 6753 | HGNC ID: HGNC:11332 | Ensembl Gene: ENSG00000278195 | OMIM ID: 182453 |
| Drug and gene relationship at DGIdb | |||
Expression of SSTR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SSTR3 | 6753 | 1553178_a_at | 0.0177 | 0.9502 | |
| GSE20347 | SSTR3 | 6753 | 214491_at | 0.0717 | 0.5353 | |
| GSE23400 | SSTR3 | 6753 | 214491_at | -0.1563 | 0.0001 | |
| GSE26886 | SSTR3 | 6753 | 214491_at | 0.2196 | 0.0122 | |
| GSE29001 | SSTR3 | 6753 | 214491_at | -0.0422 | 0.8237 | |
| GSE38129 | SSTR3 | 6753 | 214491_at | -0.0914 | 0.3109 | |
| GSE45670 | SSTR3 | 6753 | 214491_at | 0.0859 | 0.4065 | |
| GSE53622 | SSTR3 | 6753 | 10070 | 0.3473 | 0.0000 | |
| GSE53624 | SSTR3 | 6753 | 10070 | 0.3518 | 0.0000 | |
| GSE63941 | SSTR3 | 6753 | 1553178_a_at | 0.1178 | 0.2654 | |
| GSE77861 | SSTR3 | 6753 | 214491_at | -0.1025 | 0.5130 | |
| TCGA | SSTR3 | 6753 | RNAseq | -0.0753 | 0.9388 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SSTR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SSTR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SSTR3 | 6753 | 6 | 6 | 18 | |
| GSE20123 | SSTR3 | 6753 | 6 | 5 | 19 | |
| GSE43470 | SSTR3 | 6753 | 4 | 6 | 33 | |
| GSE46452 | SSTR3 | 6753 | 31 | 1 | 27 | |
| GSE47630 | SSTR3 | 6753 | 8 | 5 | 27 | |
| GSE54993 | SSTR3 | 6753 | 3 | 6 | 61 | |
| GSE54994 | SSTR3 | 6753 | 10 | 8 | 35 | |
| GSE60625 | SSTR3 | 6753 | 5 | 0 | 6 | |
| GSE74703 | SSTR3 | 6753 | 4 | 4 | 28 | |
| GSE74704 | SSTR3 | 6753 | 3 | 2 | 15 | |
| TCGA | SSTR3 | 6753 | 27 | 16 | 53 |
Total number of gains: 107; Total number of losses: 59; Total Number of normals: 322.
Somatic mutations of SSTR3:
Generating mutation plots.
Highly correlated genes for SSTR3:
Showing top 20/1063 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SSTR3 | ZNF358 | 0.768761 | 3 | 0 | 3 |
| SSTR3 | TNFSF8 | 0.735688 | 3 | 0 | 3 |
| SSTR3 | GTPBP10 | 0.731888 | 3 | 0 | 3 |
| SSTR3 | GGT5 | 0.70891 | 3 | 0 | 3 |
| SSTR3 | SYT5 | 0.698321 | 5 | 0 | 5 |
| SSTR3 | HRC | 0.696507 | 3 | 0 | 3 |
| SSTR3 | C1QTNF1-AS1 | 0.69444 | 3 | 0 | 3 |
| SSTR3 | BCAS4 | 0.693993 | 3 | 0 | 3 |
| SSTR3 | AMN | 0.690944 | 7 | 0 | 7 |
| SSTR3 | JAK3 | 0.690338 | 5 | 0 | 4 |
| SSTR3 | KCNA1 | 0.689118 | 4 | 0 | 4 |
| SSTR3 | GALNT8 | 0.688213 | 4 | 0 | 4 |
| SSTR3 | HHLA1 | 0.688199 | 4 | 0 | 3 |
| SSTR3 | ART1 | 0.688195 | 5 | 0 | 5 |
| SSTR3 | KRTAP5-8 | 0.685183 | 6 | 0 | 6 |
| SSTR3 | MVK | 0.684663 | 5 | 0 | 5 |
| SSTR3 | CHRNB2 | 0.67994 | 8 | 0 | 7 |
| SSTR3 | CD1B | 0.679317 | 3 | 0 | 3 |
| SSTR3 | CPA2 | 0.678464 | 3 | 0 | 3 |
| SSTR3 | OR10H3 | 0.677554 | 4 | 0 | 4 |
For details and further investigation, click here
