| Full name: autophagy related 4B cysteine peptidase | Alias Symbol: Apg4B|KIAA0943|DKFZp586D1822|AUTL1 | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 23192 | HGNC ID: HGNC:20790 | Ensembl Gene: ENSG00000168397 | OMIM ID: 611338 |
| Drug and gene relationship at DGIdb | |||
Expression of ATG4B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATG4B | 23192 | 204903_x_at | -0.1495 | 0.7526 | |
| GSE20347 | ATG4B | 23192 | 204903_x_at | -0.0741 | 0.5042 | |
| GSE23400 | ATG4B | 23192 | 204903_x_at | -0.0064 | 0.8932 | |
| GSE26886 | ATG4B | 23192 | 204903_x_at | -0.1497 | 0.2098 | |
| GSE29001 | ATG4B | 23192 | 204903_x_at | 0.1146 | 0.4274 | |
| GSE38129 | ATG4B | 23192 | 204903_x_at | 0.0909 | 0.4107 | |
| GSE45670 | ATG4B | 23192 | 204903_x_at | 0.2579 | 0.0211 | |
| GSE53622 | ATG4B | 23192 | 12830 | 0.0415 | 0.3473 | |
| GSE53624 | ATG4B | 23192 | 12830 | 0.0519 | 0.1870 | |
| GSE63941 | ATG4B | 23192 | 204903_x_at | 0.6714 | 0.0355 | |
| GSE77861 | ATG4B | 23192 | 204903_x_at | 0.1928 | 0.4304 | |
| GSE97050 | ATG4B | 23192 | A_33_P3335137 | 0.1624 | 0.4357 | |
| SRP007169 | ATG4B | 23192 | RNAseq | -0.2922 | 0.4322 | |
| SRP008496 | ATG4B | 23192 | RNAseq | -0.2206 | 0.3201 | |
| SRP064894 | ATG4B | 23192 | RNAseq | 0.2668 | 0.1175 | |
| SRP133303 | ATG4B | 23192 | RNAseq | 0.0410 | 0.7668 | |
| SRP159526 | ATG4B | 23192 | RNAseq | 0.1838 | 0.5774 | |
| SRP193095 | ATG4B | 23192 | RNAseq | 0.0550 | 0.6192 | |
| SRP219564 | ATG4B | 23192 | RNAseq | 0.0454 | 0.8604 | |
| TCGA | ATG4B | 23192 | RNAseq | -0.0781 | 0.1063 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATG4B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATG4B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATG4B | 23192 | 1 | 12 | 17 | |
| GSE20123 | ATG4B | 23192 | 1 | 12 | 17 | |
| GSE43470 | ATG4B | 23192 | 1 | 9 | 33 | |
| GSE46452 | ATG4B | 23192 | 0 | 5 | 54 | |
| GSE47630 | ATG4B | 23192 | 4 | 5 | 31 | |
| GSE54993 | ATG4B | 23192 | 4 | 3 | 63 | |
| GSE54994 | ATG4B | 23192 | 8 | 9 | 36 | |
| GSE60625 | ATG4B | 23192 | 0 | 3 | 8 | |
| GSE74703 | ATG4B | 23192 | 1 | 7 | 28 | |
| GSE74704 | ATG4B | 23192 | 1 | 5 | 14 | |
| TCGA | ATG4B | 23192 | 11 | 29 | 56 |
Total number of gains: 32; Total number of losses: 99; Total Number of normals: 357.
Somatic mutations of ATG4B:
Generating mutation plots.
Highly correlated genes for ATG4B:
Showing top 20/80 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATG4B | SLC9A1 | 0.654656 | 3 | 0 | 3 |
| ATG4B | B9D1 | 0.651865 | 3 | 0 | 3 |
| ATG4B | IKBKG | 0.645293 | 3 | 0 | 3 |
| ATG4B | EWSR1 | 0.635696 | 3 | 0 | 3 |
| ATG4B | FAM83F | 0.620266 | 4 | 0 | 3 |
| ATG4B | RBM42 | 0.617026 | 3 | 0 | 3 |
| ATG4B | ANKZF1 | 0.61696 | 5 | 0 | 4 |
| ATG4B | GPAA1 | 0.614456 | 5 | 0 | 4 |
| ATG4B | SLC25A17 | 0.609586 | 3 | 0 | 3 |
| ATG4B | ZNF581 | 0.606254 | 3 | 0 | 3 |
| ATG4B | LIMK1 | 0.599607 | 4 | 0 | 3 |
| ATG4B | ZNF668 | 0.598435 | 4 | 0 | 4 |
| ATG4B | AHSA1 | 0.595989 | 3 | 0 | 3 |
| ATG4B | CTDNEP1 | 0.594346 | 3 | 0 | 3 |
| ATG4B | ATAD3A | 0.593678 | 3 | 0 | 3 |
| ATG4B | UTS2R | 0.59013 | 5 | 0 | 4 |
| ATG4B | DDX11 | 0.589189 | 3 | 0 | 3 |
| ATG4B | TUSC1 | 0.587152 | 3 | 0 | 3 |
| ATG4B | TOP3B | 0.586819 | 5 | 0 | 3 |
| ATG4B | COG3 | 0.583223 | 3 | 0 | 3 |
For details and further investigation, click here
