| Full name: solute carrier family 9 member A1 | Alias Symbol: PPP1R143 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 6548 | HGNC ID: HGNC:11071 | Ensembl Gene: ENSG00000090020 | OMIM ID: 107310 |
| Drug and gene relationship at DGIdb | |||
SLC9A1 involved pathways:
Expression of SLC9A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC9A1 | 6548 | 209453_at | 0.4300 | 0.1052 | |
| GSE20347 | SLC9A1 | 6548 | 209453_at | 0.3048 | 0.0128 | |
| GSE23400 | SLC9A1 | 6548 | 209453_at | 0.2349 | 0.0000 | |
| GSE26886 | SLC9A1 | 6548 | 209453_at | 0.7149 | 0.0007 | |
| GSE29001 | SLC9A1 | 6548 | 209453_at | 0.2881 | 0.2207 | |
| GSE38129 | SLC9A1 | 6548 | 209453_at | 0.2589 | 0.0114 | |
| GSE45670 | SLC9A1 | 6548 | 209453_at | 0.6693 | 0.0002 | |
| GSE53622 | SLC9A1 | 6548 | 4404 | 0.3782 | 0.0165 | |
| GSE53624 | SLC9A1 | 6548 | 4404 | 0.5421 | 0.0000 | |
| GSE63941 | SLC9A1 | 6548 | 209453_at | -0.2926 | 0.3011 | |
| GSE77861 | SLC9A1 | 6548 | 209453_at | 0.2608 | 0.1322 | |
| GSE97050 | SLC9A1 | 6548 | A_24_P71373 | 1.0139 | 0.0780 | |
| SRP007169 | SLC9A1 | 6548 | RNAseq | 0.3639 | 0.3829 | |
| SRP008496 | SLC9A1 | 6548 | RNAseq | -0.1521 | 0.6539 | |
| SRP064894 | SLC9A1 | 6548 | RNAseq | 0.7197 | 0.0003 | |
| SRP133303 | SLC9A1 | 6548 | RNAseq | 1.1290 | 0.0000 | |
| SRP159526 | SLC9A1 | 6548 | RNAseq | 0.3153 | 0.2547 | |
| SRP193095 | SLC9A1 | 6548 | RNAseq | 0.2054 | 0.5292 | |
| SRP219564 | SLC9A1 | 6548 | RNAseq | 0.0214 | 0.9628 | |
| TCGA | SLC9A1 | 6548 | RNAseq | -0.2029 | 0.0012 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLC9A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC9A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC9A1 | 6548 | 0 | 6 | 24 | |
| GSE20123 | SLC9A1 | 6548 | 0 | 5 | 25 | |
| GSE43470 | SLC9A1 | 6548 | 3 | 6 | 34 | |
| GSE46452 | SLC9A1 | 6548 | 5 | 1 | 53 | |
| GSE47630 | SLC9A1 | 6548 | 8 | 3 | 29 | |
| GSE54993 | SLC9A1 | 6548 | 2 | 1 | 67 | |
| GSE54994 | SLC9A1 | 6548 | 10 | 4 | 39 | |
| GSE60625 | SLC9A1 | 6548 | 0 | 0 | 11 | |
| GSE74703 | SLC9A1 | 6548 | 2 | 4 | 30 | |
| GSE74704 | SLC9A1 | 6548 | 0 | 0 | 20 | |
| TCGA | SLC9A1 | 6548 | 10 | 24 | 62 |
Total number of gains: 40; Total number of losses: 54; Total Number of normals: 394.
Somatic mutations of SLC9A1:
Generating mutation plots.
Highly correlated genes for SLC9A1:
Showing top 20/1014 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC9A1 | ANLN | 0.822254 | 3 | 0 | 3 |
| SLC9A1 | ZBTB9 | 0.799893 | 3 | 0 | 3 |
| SLC9A1 | DHCR7 | 0.783401 | 3 | 0 | 3 |
| SLC9A1 | KCNAB2 | 0.783388 | 3 | 0 | 3 |
| SLC9A1 | CPT1C | 0.766035 | 3 | 0 | 3 |
| SLC9A1 | RFX1 | 0.755249 | 3 | 0 | 3 |
| SLC9A1 | LINGO1 | 0.740262 | 3 | 0 | 3 |
| SLC9A1 | SOCS7 | 0.720107 | 3 | 0 | 3 |
| SLC9A1 | ZAP70 | 0.720074 | 3 | 0 | 3 |
| SLC9A1 | RAD18 | 0.71987 | 3 | 0 | 3 |
| SLC9A1 | NANOS1 | 0.718626 | 3 | 0 | 3 |
| SLC9A1 | PALB2 | 0.718272 | 3 | 0 | 3 |
| SLC9A1 | PPIB | 0.717048 | 4 | 0 | 4 |
| SLC9A1 | GPR153 | 0.716376 | 9 | 0 | 9 |
| SLC9A1 | AJUBA | 0.715405 | 3 | 0 | 3 |
| SLC9A1 | STK4 | 0.714195 | 3 | 0 | 3 |
| SLC9A1 | IRF2BPL | 0.712911 | 3 | 0 | 3 |
| SLC9A1 | MED25 | 0.712573 | 3 | 0 | 3 |
| SLC9A1 | IFT80 | 0.709917 | 3 | 0 | 3 |
| SLC9A1 | TWIST1 | 0.707772 | 3 | 0 | 3 |
For details and further investigation, click here
