| Full name: syntaxin 10 | Alias Symbol: hsyn10|SYN10 | ||
| Type: protein-coding gene | Cytoband: 19p13.13 | ||
| Entrez ID: 8677 | HGNC ID: HGNC:11428 | Ensembl Gene: ENSG00000104915 | OMIM ID: 603765 |
| Drug and gene relationship at DGIdb | |||
Expression of STX10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STX10 | 8677 | 212625_at | 0.1720 | 0.8005 | |
| GSE20347 | STX10 | 8677 | 212625_at | -0.1557 | 0.2841 | |
| GSE23400 | STX10 | 8677 | 212625_at | 0.0677 | 0.2592 | |
| GSE26886 | STX10 | 8677 | 212625_at | -0.1025 | 0.4156 | |
| GSE29001 | STX10 | 8677 | 212625_at | -0.0478 | 0.8525 | |
| GSE38129 | STX10 | 8677 | 212625_at | -0.1170 | 0.3106 | |
| GSE45670 | STX10 | 8677 | 212625_at | 0.1380 | 0.3047 | |
| GSE53622 | STX10 | 8677 | 22736 | 0.0617 | 0.2125 | |
| GSE53624 | STX10 | 8677 | 22736 | 0.0175 | 0.8037 | |
| GSE63941 | STX10 | 8677 | 212625_at | 0.7330 | 0.0712 | |
| GSE77861 | STX10 | 8677 | 212625_at | 0.1006 | 0.5182 | |
| GSE97050 | STX10 | 8677 | A_23_P28090 | 0.1911 | 0.3774 | |
| SRP007169 | STX10 | 8677 | RNAseq | 0.0120 | 0.9812 | |
| SRP008496 | STX10 | 8677 | RNAseq | 0.0256 | 0.9380 | |
| SRP064894 | STX10 | 8677 | RNAseq | 0.6165 | 0.0555 | |
| SRP133303 | STX10 | 8677 | RNAseq | -0.0860 | 0.5828 | |
| SRP159526 | STX10 | 8677 | RNAseq | -0.1458 | 0.5830 | |
| SRP193095 | STX10 | 8677 | RNAseq | -0.1035 | 0.3044 | |
| SRP219564 | STX10 | 8677 | RNAseq | 0.3284 | 0.5113 | |
| TCGA | STX10 | 8677 | RNAseq | 0.1010 | 0.1342 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STX10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STX10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STX10 | 8677 | 4 | 2 | 24 | |
| GSE20123 | STX10 | 8677 | 3 | 1 | 26 | |
| GSE43470 | STX10 | 8677 | 2 | 6 | 35 | |
| GSE46452 | STX10 | 8677 | 47 | 1 | 11 | |
| GSE47630 | STX10 | 8677 | 4 | 7 | 29 | |
| GSE54993 | STX10 | 8677 | 16 | 3 | 51 | |
| GSE54994 | STX10 | 8677 | 6 | 13 | 34 | |
| GSE60625 | STX10 | 8677 | 9 | 0 | 2 | |
| GSE74703 | STX10 | 8677 | 2 | 4 | 30 | |
| GSE74704 | STX10 | 8677 | 0 | 1 | 19 | |
| TCGA | STX10 | 8677 | 18 | 13 | 65 |
Total number of gains: 111; Total number of losses: 51; Total Number of normals: 326.
Somatic mutations of STX10:
Generating mutation plots.
Highly correlated genes for STX10:
Showing top 20/328 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STX10 | FNTA | 0.821544 | 3 | 0 | 3 |
| STX10 | SNRPD3 | 0.805333 | 3 | 0 | 3 |
| STX10 | KIAA0556 | 0.773213 | 3 | 0 | 3 |
| STX10 | ATG4C | 0.772945 | 3 | 0 | 3 |
| STX10 | ZNF3 | 0.766058 | 3 | 0 | 3 |
| STX10 | PARK7 | 0.758051 | 3 | 0 | 3 |
| STX10 | TMEM219 | 0.753004 | 3 | 0 | 3 |
| STX10 | SRSF10 | 0.748939 | 3 | 0 | 3 |
| STX10 | DPCD | 0.741419 | 3 | 0 | 3 |
| STX10 | MRPL51 | 0.73998 | 3 | 0 | 3 |
| STX10 | BUD31 | 0.739623 | 4 | 0 | 3 |
| STX10 | KDM2A | 0.737967 | 3 | 0 | 3 |
| STX10 | DNAJC11 | 0.737081 | 4 | 0 | 3 |
| STX10 | MRI1 | 0.730417 | 4 | 0 | 3 |
| STX10 | LSM10 | 0.724816 | 3 | 0 | 3 |
| STX10 | EIF5A | 0.723121 | 3 | 0 | 3 |
| STX10 | ATF1 | 0.722063 | 3 | 0 | 3 |
| STX10 | PNKD | 0.722046 | 3 | 0 | 3 |
| STX10 | GMCL1 | 0.719162 | 3 | 0 | 3 |
| STX10 | GET4 | 0.718364 | 3 | 0 | 3 |
For details and further investigation, click here
