| Full name: mitochondrial ribosomal protein L44 | Alias Symbol: FLJ12701|FLJ13990 | ||
| Type: protein-coding gene | Cytoband: 2q36.1 | ||
| Entrez ID: 65080 | HGNC ID: HGNC:16650 | Ensembl Gene: ENSG00000135900 | OMIM ID: 611849 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPL44:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL44 | 65080 | 222555_s_at | -0.1966 | 0.7789 | |
| GSE20347 | MRPL44 | 65080 | 218202_x_at | -0.1389 | 0.1618 | |
| GSE23400 | MRPL44 | 65080 | 218202_x_at | 0.0040 | 0.9151 | |
| GSE26886 | MRPL44 | 65080 | 222555_s_at | -0.3489 | 0.1819 | |
| GSE29001 | MRPL44 | 65080 | 218202_x_at | -0.2207 | 0.1945 | |
| GSE38129 | MRPL44 | 65080 | 218202_x_at | -0.1043 | 0.1838 | |
| GSE45670 | MRPL44 | 65080 | 222555_s_at | 0.1411 | 0.3937 | |
| GSE53622 | MRPL44 | 65080 | 82866 | 0.1563 | 0.0246 | |
| GSE53624 | MRPL44 | 65080 | 82866 | 0.0150 | 0.8598 | |
| GSE63941 | MRPL44 | 65080 | 222555_s_at | 0.5121 | 0.0868 | |
| GSE77861 | MRPL44 | 65080 | 222555_s_at | -0.0073 | 0.9880 | |
| GSE97050 | MRPL44 | 65080 | A_23_P90589 | 0.3758 | 0.2957 | |
| SRP007169 | MRPL44 | 65080 | RNAseq | -0.4910 | 0.2357 | |
| SRP008496 | MRPL44 | 65080 | RNAseq | -0.3161 | 0.2453 | |
| SRP064894 | MRPL44 | 65080 | RNAseq | -0.0609 | 0.6120 | |
| SRP133303 | MRPL44 | 65080 | RNAseq | 0.1903 | 0.1170 | |
| SRP159526 | MRPL44 | 65080 | RNAseq | -0.2419 | 0.3384 | |
| SRP193095 | MRPL44 | 65080 | RNAseq | -0.3136 | 0.0057 | |
| SRP219564 | MRPL44 | 65080 | RNAseq | -0.0084 | 0.9721 | |
| TCGA | MRPL44 | 65080 | RNAseq | 0.0112 | 0.8414 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPL44 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL44:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL44 | 65080 | 2 | 12 | 16 | |
| GSE20123 | MRPL44 | 65080 | 2 | 12 | 16 | |
| GSE43470 | MRPL44 | 65080 | 0 | 7 | 36 | |
| GSE46452 | MRPL44 | 65080 | 0 | 5 | 54 | |
| GSE47630 | MRPL44 | 65080 | 4 | 5 | 31 | |
| GSE54993 | MRPL44 | 65080 | 1 | 2 | 67 | |
| GSE54994 | MRPL44 | 65080 | 7 | 10 | 36 | |
| GSE60625 | MRPL44 | 65080 | 3 | 0 | 8 | |
| GSE74703 | MRPL44 | 65080 | 0 | 6 | 30 | |
| GSE74704 | MRPL44 | 65080 | 2 | 6 | 12 | |
| TCGA | MRPL44 | 65080 | 13 | 27 | 56 |
Total number of gains: 34; Total number of losses: 92; Total Number of normals: 362.
Somatic mutations of MRPL44:
Generating mutation plots.
Highly correlated genes for MRPL44:
Showing top 20/436 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL44 | SMU1 | 0.80702 | 3 | 0 | 3 |
| MRPL44 | SLC25A24 | 0.77353 | 3 | 0 | 3 |
| MRPL44 | ATG4C | 0.770644 | 3 | 0 | 3 |
| MRPL44 | TTC39B | 0.736876 | 3 | 0 | 3 |
| MRPL44 | HMG20A | 0.733452 | 3 | 0 | 3 |
| MRPL44 | ADAM9 | 0.730607 | 3 | 0 | 3 |
| MRPL44 | TBCC | 0.725636 | 3 | 0 | 3 |
| MRPL44 | CAPN2 | 0.723662 | 3 | 0 | 3 |
| MRPL44 | DCTN2 | 0.722606 | 3 | 0 | 3 |
| MRPL44 | ATMIN | 0.718917 | 3 | 0 | 3 |
| MRPL44 | MTFMT | 0.717589 | 3 | 0 | 3 |
| MRPL44 | PRELID1 | 0.711968 | 3 | 0 | 3 |
| MRPL44 | TRAF7 | 0.711124 | 3 | 0 | 3 |
| MRPL44 | ELK3 | 0.707615 | 4 | 0 | 3 |
| MRPL44 | CD163L1 | 0.707584 | 3 | 0 | 3 |
| MRPL44 | MRPS27 | 0.707196 | 5 | 0 | 5 |
| MRPL44 | CPA3 | 0.704769 | 3 | 0 | 3 |
| MRPL44 | PMF1 | 0.702661 | 4 | 0 | 4 |
| MRPL44 | DHX37 | 0.701792 | 3 | 0 | 3 |
| MRPL44 | SERPINB5 | 0.699948 | 3 | 0 | 3 |
For details and further investigation, click here
