| Full name: charged multivesicular body protein 7 | Alias Symbol: MGC29816 | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 91782 | HGNC ID: HGNC:28439 | Ensembl Gene: ENSG00000147457 | OMIM ID: 611130 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CHMP7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHMP7 | 91782 | 212313_at | 0.2525 | 0.2643 | |
| GSE20347 | CHMP7 | 91782 | 212313_at | 0.2651 | 0.0716 | |
| GSE23400 | CHMP7 | 91782 | 212313_at | 0.1610 | 0.0160 | |
| GSE26886 | CHMP7 | 91782 | 212313_at | 0.1144 | 0.4603 | |
| GSE29001 | CHMP7 | 91782 | 212313_at | 0.2984 | 0.3136 | |
| GSE38129 | CHMP7 | 91782 | 212313_at | -0.0285 | 0.8648 | |
| GSE45670 | CHMP7 | 91782 | 212313_at | 0.0764 | 0.6118 | |
| GSE53622 | CHMP7 | 91782 | 16273 | 0.1891 | 0.0064 | |
| GSE53624 | CHMP7 | 91782 | 16273 | 0.2249 | 0.0015 | |
| GSE63941 | CHMP7 | 91782 | 212313_at | -0.7781 | 0.0450 | |
| GSE77861 | CHMP7 | 91782 | 212313_at | 0.0993 | 0.6001 | |
| GSE97050 | CHMP7 | 91782 | A_23_P303203 | 0.3634 | 0.2156 | |
| SRP007169 | CHMP7 | 91782 | RNAseq | 1.5250 | 0.0194 | |
| SRP008496 | CHMP7 | 91782 | RNAseq | 1.4939 | 0.0010 | |
| SRP064894 | CHMP7 | 91782 | RNAseq | 0.2891 | 0.0938 | |
| SRP133303 | CHMP7 | 91782 | RNAseq | -0.2242 | 0.1539 | |
| SRP159526 | CHMP7 | 91782 | RNAseq | -0.1208 | 0.5503 | |
| SRP193095 | CHMP7 | 91782 | RNAseq | 0.0693 | 0.5638 | |
| SRP219564 | CHMP7 | 91782 | RNAseq | 0.0256 | 0.9545 | |
| TCGA | CHMP7 | 91782 | RNAseq | -0.1020 | 0.0495 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CHMP7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHMP7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHMP7 | 91782 | 4 | 12 | 14 | |
| GSE20123 | CHMP7 | 91782 | 4 | 12 | 14 | |
| GSE43470 | CHMP7 | 91782 | 4 | 9 | 30 | |
| GSE46452 | CHMP7 | 91782 | 13 | 13 | 33 | |
| GSE47630 | CHMP7 | 91782 | 10 | 8 | 22 | |
| GSE54993 | CHMP7 | 91782 | 2 | 14 | 54 | |
| GSE54994 | CHMP7 | 91782 | 8 | 18 | 27 | |
| GSE60625 | CHMP7 | 91782 | 3 | 0 | 8 | |
| GSE74703 | CHMP7 | 91782 | 4 | 7 | 25 | |
| GSE74704 | CHMP7 | 91782 | 3 | 8 | 9 | |
| TCGA | CHMP7 | 91782 | 15 | 42 | 39 |
Total number of gains: 70; Total number of losses: 143; Total Number of normals: 275.
Somatic mutations of CHMP7:
Generating mutation plots.
Highly correlated genes for CHMP7:
Showing top 20/418 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHMP7 | PEG10 | 0.801586 | 3 | 0 | 3 |
| CHMP7 | UBE2M | 0.762948 | 3 | 0 | 3 |
| CHMP7 | MCM3AP | 0.760977 | 4 | 0 | 4 |
| CHMP7 | ATG4C | 0.759353 | 3 | 0 | 3 |
| CHMP7 | ZC3HC1 | 0.730016 | 3 | 0 | 3 |
| CHMP7 | FAM111A | 0.72986 | 3 | 0 | 3 |
| CHMP7 | CAV2 | 0.728782 | 3 | 0 | 3 |
| CHMP7 | CDC42SE2 | 0.718676 | 3 | 0 | 3 |
| CHMP7 | NBAS | 0.714446 | 3 | 0 | 3 |
| CHMP7 | KLF13 | 0.711882 | 3 | 0 | 3 |
| CHMP7 | TUBE1 | 0.710058 | 3 | 0 | 3 |
| CHMP7 | PDGFRB | 0.709904 | 3 | 0 | 3 |
| CHMP7 | SLC7A6 | 0.709642 | 4 | 0 | 4 |
| CHMP7 | C2CD2 | 0.704537 | 3 | 0 | 3 |
| CHMP7 | SAP30L | 0.703652 | 3 | 0 | 3 |
| CHMP7 | MED9 | 0.700351 | 3 | 0 | 3 |
| CHMP7 | CDC26 | 0.700259 | 3 | 0 | 3 |
| CHMP7 | PRR3 | 0.699288 | 3 | 0 | 3 |
| CHMP7 | UBE3C | 0.698501 | 4 | 0 | 3 |
| CHMP7 | ANAPC11 | 0.6953 | 4 | 0 | 4 |
For details and further investigation, click here
