| Full name: autophagy related 7 | Alias Symbol: GSA7|DKFZp434N0735 | ||
| Type: protein-coding gene | Cytoband: 3p25.3 | ||
| Entrez ID: 10533 | HGNC ID: HGNC:16935 | Ensembl Gene: ENSG00000197548 | OMIM ID: 608760 |
| Drug and gene relationship at DGIdb | |||
Expression of ATG7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATG7 | 10533 | 224025_s_at | 0.0852 | 0.8125 | |
| GSE20347 | ATG7 | 10533 | 218673_s_at | -0.3521 | 0.0011 | |
| GSE23400 | ATG7 | 10533 | 218673_s_at | 0.0138 | 0.7923 | |
| GSE26886 | ATG7 | 10533 | 224025_s_at | -0.7726 | 0.0001 | |
| GSE29001 | ATG7 | 10533 | 218673_s_at | -0.2912 | 0.0868 | |
| GSE38129 | ATG7 | 10533 | 218673_s_at | -0.1866 | 0.0327 | |
| GSE45670 | ATG7 | 10533 | 224025_s_at | 0.1319 | 0.1436 | |
| GSE53622 | ATG7 | 10533 | 2254 | -0.2000 | 0.0169 | |
| GSE53624 | ATG7 | 10533 | 2254 | -0.3123 | 0.0004 | |
| GSE63941 | ATG7 | 10533 | 218673_s_at | 0.5475 | 0.4274 | |
| GSE77861 | ATG7 | 10533 | 224025_s_at | -0.2634 | 0.2054 | |
| GSE97050 | ATG7 | 10533 | A_24_P944827 | 0.0298 | 0.9072 | |
| SRP007169 | ATG7 | 10533 | RNAseq | -0.8971 | 0.0394 | |
| SRP008496 | ATG7 | 10533 | RNAseq | -1.0260 | 0.0001 | |
| SRP064894 | ATG7 | 10533 | RNAseq | 0.2654 | 0.1671 | |
| SRP133303 | ATG7 | 10533 | RNAseq | -0.0599 | 0.6613 | |
| SRP159526 | ATG7 | 10533 | RNAseq | -0.6790 | 0.0008 | |
| SRP193095 | ATG7 | 10533 | RNAseq | -0.1735 | 0.1207 | |
| SRP219564 | ATG7 | 10533 | RNAseq | -0.2047 | 0.4415 | |
| TCGA | ATG7 | 10533 | RNAseq | -0.1221 | 0.0265 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ATG7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATG7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATG7 | 10533 | 1 | 18 | 11 | |
| GSE20123 | ATG7 | 10533 | 1 | 19 | 10 | |
| GSE43470 | ATG7 | 10533 | 0 | 21 | 22 | |
| GSE46452 | ATG7 | 10533 | 2 | 17 | 40 | |
| GSE47630 | ATG7 | 10533 | 2 | 23 | 15 | |
| GSE54993 | ATG7 | 10533 | 6 | 1 | 63 | |
| GSE54994 | ATG7 | 10533 | 1 | 33 | 19 | |
| GSE60625 | ATG7 | 10533 | 5 | 0 | 6 | |
| GSE74703 | ATG7 | 10533 | 0 | 17 | 19 | |
| GSE74704 | ATG7 | 10533 | 1 | 10 | 9 | |
| TCGA | ATG7 | 10533 | 2 | 71 | 23 |
Total number of gains: 21; Total number of losses: 230; Total Number of normals: 237.
Somatic mutations of ATG7:
Generating mutation plots.
Highly correlated genes for ATG7:
Showing top 20/654 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATG7 | APOBR | 0.808081 | 3 | 0 | 3 |
| ATG7 | RTN3 | 0.805416 | 3 | 0 | 3 |
| ATG7 | COPA | 0.79542 | 3 | 0 | 3 |
| ATG7 | AASDHPPT | 0.778854 | 4 | 0 | 4 |
| ATG7 | PPP2CB | 0.760285 | 3 | 0 | 3 |
| ATG7 | GLOD4 | 0.75792 | 3 | 0 | 3 |
| ATG7 | PRPF38A | 0.756129 | 3 | 0 | 3 |
| ATG7 | WDR20 | 0.74678 | 3 | 0 | 3 |
| ATG7 | CLDN2 | 0.744334 | 3 | 0 | 3 |
| ATG7 | MAP4K4 | 0.736238 | 3 | 0 | 3 |
| ATG7 | ZNF90 | 0.731202 | 3 | 0 | 3 |
| ATG7 | GPR37L1 | 0.727806 | 3 | 0 | 3 |
| ATG7 | CCDC85C | 0.727468 | 3 | 0 | 3 |
| ATG7 | UBR2 | 0.720669 | 3 | 0 | 3 |
| ATG7 | RPS9 | 0.717904 | 3 | 0 | 3 |
| ATG7 | SREBF2 | 0.717309 | 5 | 0 | 4 |
| ATG7 | EGLN1 | 0.716689 | 3 | 0 | 3 |
| ATG7 | LAMP2 | 0.714687 | 5 | 0 | 5 |
| ATG7 | HIC2 | 0.714683 | 3 | 0 | 3 |
| ATG7 | TMEM234 | 0.708862 | 3 | 0 | 3 |
For details and further investigation, click here
