| Full name: reticulon 3 | Alias Symbol: NSPL2|NSPLII|ASYIP|HAP|RTN3-A1 | ||
| Type: protein-coding gene | Cytoband: 11q13 | ||
| Entrez ID: 10313 | HGNC ID: HGNC:10469 | Ensembl Gene: ENSG00000133318 | OMIM ID: 604249 |
| Drug and gene relationship at DGIdb | |||
Expression of RTN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTN3 | 10313 | 219549_s_at | 0.0009 | 0.9990 | |
| GSE20347 | RTN3 | 10313 | 219549_s_at | -0.0641 | 0.8052 | |
| GSE23400 | RTN3 | 10313 | 219549_s_at | 0.1918 | 0.0355 | |
| GSE26886 | RTN3 | 10313 | 219549_s_at | -0.8071 | 0.0132 | |
| GSE29001 | RTN3 | 10313 | 219549_s_at | 0.0038 | 0.9885 | |
| GSE38129 | RTN3 | 10313 | 219549_s_at | -0.1272 | 0.5789 | |
| GSE45670 | RTN3 | 10313 | 224564_s_at | 0.1444 | 0.3134 | |
| GSE53622 | RTN3 | 10313 | 4139 | -0.1022 | 0.1906 | |
| GSE53624 | RTN3 | 10313 | 53381 | 0.0322 | 0.6432 | |
| GSE63941 | RTN3 | 10313 | 224564_s_at | 0.5707 | 0.1852 | |
| GSE77861 | RTN3 | 10313 | 224564_s_at | -0.0114 | 0.9590 | |
| GSE97050 | RTN3 | 10313 | A_33_P3362371 | 0.0689 | 0.7357 | |
| SRP007169 | RTN3 | 10313 | RNAseq | -0.6034 | 0.0487 | |
| SRP008496 | RTN3 | 10313 | RNAseq | -0.4273 | 0.0525 | |
| SRP064894 | RTN3 | 10313 | RNAseq | -0.0157 | 0.9092 | |
| SRP133303 | RTN3 | 10313 | RNAseq | 0.2589 | 0.1505 | |
| SRP159526 | RTN3 | 10313 | RNAseq | 0.1247 | 0.4943 | |
| SRP193095 | RTN3 | 10313 | RNAseq | 0.0132 | 0.9129 | |
| SRP219564 | RTN3 | 10313 | RNAseq | -0.2049 | 0.4937 | |
| TCGA | RTN3 | 10313 | RNAseq | 0.0079 | 0.8543 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RTN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTN3 | 10313 | 6 | 5 | 19 | |
| GSE20123 | RTN3 | 10313 | 6 | 5 | 19 | |
| GSE43470 | RTN3 | 10313 | 1 | 4 | 38 | |
| GSE46452 | RTN3 | 10313 | 8 | 4 | 47 | |
| GSE47630 | RTN3 | 10313 | 3 | 7 | 30 | |
| GSE54993 | RTN3 | 10313 | 3 | 0 | 67 | |
| GSE54994 | RTN3 | 10313 | 5 | 5 | 43 | |
| GSE60625 | RTN3 | 10313 | 0 | 4 | 7 | |
| GSE74703 | RTN3 | 10313 | 1 | 2 | 33 | |
| GSE74704 | RTN3 | 10313 | 4 | 3 | 13 | |
| TCGA | RTN3 | 10313 | 17 | 11 | 68 |
Total number of gains: 54; Total number of losses: 50; Total Number of normals: 384.
Somatic mutations of RTN3:
Generating mutation plots.
Highly correlated genes for RTN3:
Showing top 20/162 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTN3 | DAD1 | 0.811513 | 3 | 0 | 3 |
| RTN3 | ATG7 | 0.805416 | 3 | 0 | 3 |
| RTN3 | MRPL27 | 0.785451 | 3 | 0 | 3 |
| RTN3 | GMPR2 | 0.766696 | 4 | 0 | 4 |
| RTN3 | EGLN1 | 0.763747 | 3 | 0 | 3 |
| RTN3 | LETMD1 | 0.752311 | 3 | 0 | 3 |
| RTN3 | HEATR5A | 0.75153 | 3 | 0 | 3 |
| RTN3 | RALBP1 | 0.743371 | 3 | 0 | 3 |
| RTN3 | CD63 | 0.742835 | 3 | 0 | 3 |
| RTN3 | GLUD2 | 0.738105 | 3 | 0 | 3 |
| RTN3 | EMP2 | 0.733853 | 3 | 0 | 3 |
| RTN3 | ANG | 0.728838 | 4 | 0 | 4 |
| RTN3 | CASP8AP2 | 0.727958 | 3 | 0 | 3 |
| RTN3 | MDN1 | 0.721292 | 3 | 0 | 3 |
| RTN3 | USP8 | 0.721028 | 3 | 0 | 3 |
| RTN3 | SLC25A5 | 0.714237 | 3 | 0 | 3 |
| RTN3 | PRELID1 | 0.712275 | 3 | 0 | 3 |
| RTN3 | KDSR | 0.708838 | 3 | 0 | 3 |
| RTN3 | RNF139 | 0.707216 | 3 | 0 | 3 |
| RTN3 | RBX1 | 0.706189 | 3 | 0 | 3 |
For details and further investigation, click here
