| Full name: claudin 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xq22.3 | ||
| Entrez ID: 9075 | HGNC ID: HGNC:2041 | Ensembl Gene: ENSG00000165376 | OMIM ID: 300520 |
| Drug and gene relationship at DGIdb | |||
CLDN2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04530 | Tight junction |
Expression of CLDN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLDN2 | 9075 | 223509_at | -0.0630 | 0.8184 | |
| GSE26886 | CLDN2 | 9075 | 223509_at | -0.1368 | 0.1820 | |
| GSE45670 | CLDN2 | 9075 | 223509_at | 0.0806 | 0.3268 | |
| GSE53622 | CLDN2 | 9075 | 13644 | 0.6930 | 0.0000 | |
| GSE53624 | CLDN2 | 9075 | 13644 | 0.8529 | 0.0000 | |
| GSE63941 | CLDN2 | 9075 | 223509_at | -0.1342 | 0.4395 | |
| GSE77861 | CLDN2 | 9075 | 223509_at | -0.1742 | 0.0451 | |
| GSE97050 | CLDN2 | 9075 | A_33_P3249046 | 0.0780 | 0.7312 | |
| SRP133303 | CLDN2 | 9075 | RNAseq | -0.4007 | 0.4140 | |
| TCGA | CLDN2 | 9075 | RNAseq | -1.2658 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CLDN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLDN2:
No record found for this gene.
Somatic mutations of CLDN2:
Generating mutation plots.
Highly correlated genes for CLDN2:
Showing top 20/129 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLDN2 | KCND1 | 0.797282 | 3 | 0 | 3 |
| CLDN2 | CLDND2 | 0.795801 | 3 | 0 | 3 |
| CLDN2 | GPR37L1 | 0.774017 | 3 | 0 | 3 |
| CLDN2 | TRIM3 | 0.755466 | 3 | 0 | 3 |
| CLDN2 | ATG7 | 0.744334 | 3 | 0 | 3 |
| CLDN2 | NUDT9 | 0.739793 | 3 | 0 | 3 |
| CLDN2 | SCARF1 | 0.733201 | 3 | 0 | 3 |
| CLDN2 | ARHGEF6 | 0.730224 | 3 | 0 | 3 |
| CLDN2 | DCAF10 | 0.726077 | 3 | 0 | 3 |
| CLDN2 | BACH2 | 0.725908 | 3 | 0 | 3 |
| CLDN2 | EIF1AY | 0.717654 | 3 | 0 | 3 |
| CLDN2 | RAP1GDS1 | 0.717224 | 3 | 0 | 3 |
| CLDN2 | ZNF445 | 0.713405 | 3 | 0 | 3 |
| CLDN2 | APIP | 0.708712 | 3 | 0 | 3 |
| CLDN2 | SPRYD4 | 0.70696 | 3 | 0 | 3 |
| CLDN2 | KRTAP5-8 | 0.706908 | 3 | 0 | 3 |
| CLDN2 | FBXO32 | 0.705783 | 3 | 0 | 3 |
| CLDN2 | CYP27A1 | 0.704685 | 3 | 0 | 3 |
| CLDN2 | USP9Y | 0.704539 | 3 | 0 | 3 |
| CLDN2 | GRHPR | 0.693526 | 4 | 0 | 3 |
For details and further investigation, click here
