| Full name: protein phosphatase 2 catalytic subunit beta | Alias Symbol: PP2Abeta | ||
| Type: protein-coding gene | Cytoband: 8p12 | ||
| Entrez ID: 5516 | HGNC ID: HGNC:9300 | Ensembl Gene: ENSG00000104695 | OMIM ID: 176916 |
| Drug and gene relationship at DGIdb | |||
PPP2CB involved pathways:
Expression of PPP2CB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP2CB | 5516 | 201375_s_at | -0.4209 | 0.1052 | |
| GSE20347 | PPP2CB | 5516 | 201375_s_at | -0.4441 | 0.0017 | |
| GSE23400 | PPP2CB | 5516 | 201375_s_at | -0.4377 | 0.0000 | |
| GSE26886 | PPP2CB | 5516 | 201375_s_at | -1.1310 | 0.0000 | |
| GSE29001 | PPP2CB | 5516 | 201375_s_at | -0.3844 | 0.1814 | |
| GSE38129 | PPP2CB | 5516 | 201375_s_at | -0.5362 | 0.0000 | |
| GSE45670 | PPP2CB | 5516 | 201375_s_at | -0.3467 | 0.0218 | |
| GSE63941 | PPP2CB | 5516 | 201375_s_at | -1.0656 | 0.0145 | |
| GSE77861 | PPP2CB | 5516 | 201375_s_at | -0.3643 | 0.1747 | |
| GSE97050 | PPP2CB | 5516 | A_23_P308097 | -0.2989 | 0.2569 | |
| SRP007169 | PPP2CB | 5516 | RNAseq | -1.6942 | 0.0000 | |
| SRP008496 | PPP2CB | 5516 | RNAseq | -1.4656 | 0.0000 | |
| SRP064894 | PPP2CB | 5516 | RNAseq | -0.6445 | 0.0001 | |
| SRP133303 | PPP2CB | 5516 | RNAseq | -0.6871 | 0.0002 | |
| SRP159526 | PPP2CB | 5516 | RNAseq | -0.8238 | 0.0001 | |
| SRP193095 | PPP2CB | 5516 | RNAseq | -0.8100 | 0.0000 | |
| SRP219564 | PPP2CB | 5516 | RNAseq | -0.9909 | 0.0087 | |
| TCGA | PPP2CB | 5516 | RNAseq | -0.0925 | 0.0511 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by PPP2CB expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PPP2CB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP2CB | 5516 | 4 | 11 | 15 | |
| GSE20123 | PPP2CB | 5516 | 4 | 11 | 15 | |
| GSE43470 | PPP2CB | 5516 | 4 | 7 | 32 | |
| GSE46452 | PPP2CB | 5516 | 13 | 13 | 33 | |
| GSE47630 | PPP2CB | 5516 | 10 | 8 | 22 | |
| GSE54993 | PPP2CB | 5516 | 2 | 15 | 53 | |
| GSE54994 | PPP2CB | 5516 | 11 | 16 | 26 | |
| GSE60625 | PPP2CB | 5516 | 3 | 0 | 8 | |
| GSE74703 | PPP2CB | 5516 | 4 | 6 | 26 | |
| GSE74704 | PPP2CB | 5516 | 3 | 7 | 10 | |
| TCGA | PPP2CB | 5516 | 19 | 40 | 37 |
Total number of gains: 77; Total number of losses: 134; Total Number of normals: 277.
Somatic mutations of PPP2CB:
Generating mutation plots.
Highly correlated genes for PPP2CB:
Showing top 20/1007 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP2CB | HERPUD1 | 0.81002 | 3 | 0 | 3 |
| PPP2CB | NMT2 | 0.792745 | 3 | 0 | 3 |
| PPP2CB | AK3 | 0.774606 | 4 | 0 | 4 |
| PPP2CB | PDIK1L | 0.764177 | 3 | 0 | 3 |
| PPP2CB | RHBDD1 | 0.764047 | 3 | 0 | 3 |
| PPP2CB | ATG7 | 0.760285 | 3 | 0 | 3 |
| PPP2CB | ME3 | 0.755494 | 3 | 0 | 3 |
| PPP2CB | SGMS2 | 0.750077 | 6 | 0 | 6 |
| PPP2CB | TMEM43 | 0.743106 | 4 | 0 | 3 |
| PPP2CB | ESYT2 | 0.742239 | 4 | 0 | 3 |
| PPP2CB | KLHL15 | 0.736261 | 3 | 0 | 3 |
| PPP2CB | HOOK3 | 0.731108 | 6 | 0 | 5 |
| PPP2CB | DUSP11 | 0.731045 | 3 | 0 | 3 |
| PPP2CB | SCOC | 0.725712 | 7 | 0 | 7 |
| PPP2CB | PEX11B | 0.725144 | 4 | 0 | 3 |
| PPP2CB | KCTD6 | 0.725135 | 4 | 0 | 3 |
| PPP2CB | RELL1 | 0.72233 | 3 | 0 | 3 |
| PPP2CB | ABCG2 | 0.72196 | 3 | 0 | 3 |
| PPP2CB | PGM1 | 0.717306 | 7 | 0 | 7 |
| PPP2CB | NAA20 | 0.713578 | 3 | 0 | 3 |
For details and further investigation, click here
