| Full name: WD repeat domain 20 | Alias Symbol: DMR|MGC33177|FLJ33659 | ||
| Type: protein-coding gene | Cytoband: 14q32.31 | ||
| Entrez ID: 91833 | HGNC ID: HGNC:19667 | Ensembl Gene: ENSG00000140153 | OMIM ID: 617741 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of WDR20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR20 | 91833 | 227693_at | -0.1776 | 0.6937 | |
| GSE26886 | WDR20 | 91833 | 227693_at | -0.1361 | 0.6084 | |
| GSE45670 | WDR20 | 91833 | 227693_at | 0.0822 | 0.5475 | |
| GSE53622 | WDR20 | 91833 | 12213 | -0.0332 | 0.6592 | |
| GSE53624 | WDR20 | 91833 | 12213 | -0.3112 | 0.0000 | |
| GSE63941 | WDR20 | 91833 | 227693_at | 0.2351 | 0.6808 | |
| GSE77861 | WDR20 | 91833 | 227693_at | -0.0944 | 0.8358 | |
| GSE97050 | WDR20 | 91833 | A_23_P205255 | 0.1564 | 0.4780 | |
| SRP007169 | WDR20 | 91833 | RNAseq | -0.8329 | 0.0137 | |
| SRP008496 | WDR20 | 91833 | RNAseq | -0.6571 | 0.0024 | |
| SRP064894 | WDR20 | 91833 | RNAseq | -0.4337 | 0.0012 | |
| SRP133303 | WDR20 | 91833 | RNAseq | -0.0998 | 0.3007 | |
| SRP159526 | WDR20 | 91833 | RNAseq | -0.3679 | 0.1918 | |
| SRP193095 | WDR20 | 91833 | RNAseq | -0.3235 | 0.0005 | |
| SRP219564 | WDR20 | 91833 | RNAseq | -0.1594 | 0.5935 | |
| TCGA | WDR20 | 91833 | RNAseq | -0.0728 | 0.1843 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDR20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR20 | 91833 | 11 | 5 | 14 | |
| GSE20123 | WDR20 | 91833 | 10 | 4 | 16 | |
| GSE43470 | WDR20 | 91833 | 7 | 4 | 32 | |
| GSE46452 | WDR20 | 91833 | 18 | 4 | 37 | |
| GSE47630 | WDR20 | 91833 | 10 | 9 | 21 | |
| GSE54993 | WDR20 | 91833 | 3 | 8 | 59 | |
| GSE54994 | WDR20 | 91833 | 21 | 4 | 28 | |
| GSE60625 | WDR20 | 91833 | 0 | 2 | 9 | |
| GSE74703 | WDR20 | 91833 | 6 | 3 | 27 | |
| GSE74704 | WDR20 | 91833 | 5 | 3 | 12 | |
| TCGA | WDR20 | 91833 | 32 | 19 | 45 |
Total number of gains: 123; Total number of losses: 65; Total Number of normals: 300.
Somatic mutations of WDR20:
Generating mutation plots.
Highly correlated genes for WDR20:
Showing top 20/192 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR20 | C11orf54 | 0.829967 | 3 | 0 | 3 |
| WDR20 | CUL2 | 0.76852 | 3 | 0 | 3 |
| WDR20 | DCTN4 | 0.75614 | 3 | 0 | 3 |
| WDR20 | ATG7 | 0.74678 | 3 | 0 | 3 |
| WDR20 | HUS1 | 0.746775 | 3 | 0 | 3 |
| WDR20 | MTUS1 | 0.741811 | 3 | 0 | 3 |
| WDR20 | CRYZ | 0.740359 | 3 | 0 | 3 |
| WDR20 | MRPL46 | 0.731227 | 4 | 0 | 3 |
| WDR20 | CD2BP2 | 0.730817 | 3 | 0 | 3 |
| WDR20 | ENDOD1 | 0.72801 | 3 | 0 | 3 |
| WDR20 | MBLAC1 | 0.726483 | 3 | 0 | 3 |
| WDR20 | WDR36 | 0.725585 | 3 | 0 | 3 |
| WDR20 | IGIP | 0.725165 | 3 | 0 | 3 |
| WDR20 | KLF3 | 0.72376 | 3 | 0 | 3 |
| WDR20 | NUDT14 | 0.721499 | 4 | 0 | 4 |
| WDR20 | STOML2 | 0.717239 | 3 | 0 | 3 |
| WDR20 | ASCC3 | 0.717045 | 3 | 0 | 3 |
| WDR20 | RNF144B | 0.716912 | 3 | 0 | 3 |
| WDR20 | PAPPA | 0.713882 | 3 | 0 | 3 |
| WDR20 | PRKAR2A | 0.710971 | 3 | 0 | 3 |
For details and further investigation, click here
