| Full name: ATP synthase mitochondrial F1 complex assembly factor 1 | Alias Symbol: FLJ22351|Atp11p|ATP11 | ||
| Type: protein-coding gene | Cytoband: 1p33 | ||
| Entrez ID: 64756 | HGNC ID: HGNC:18803 | Ensembl Gene: ENSG00000123472 | OMIM ID: 608917 |
| Drug and gene relationship at DGIdb | |||
Expression of ATPAF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATPAF1 | 64756 | 224729_s_at | 0.0213 | 0.9753 | |
| GSE26886 | ATPAF1 | 64756 | 224729_s_at | 0.4515 | 0.0536 | |
| GSE45670 | ATPAF1 | 64756 | 224729_s_at | -0.2765 | 0.0268 | |
| GSE53622 | ATPAF1 | 64756 | 52793 | -0.2865 | 0.0013 | |
| GSE53624 | ATPAF1 | 64756 | 52793 | -0.1233 | 0.1079 | |
| GSE63941 | ATPAF1 | 64756 | 224729_s_at | 0.0587 | 0.8792 | |
| GSE77861 | ATPAF1 | 64756 | 224729_s_at | -0.1244 | 0.7630 | |
| GSE97050 | ATPAF1 | 64756 | A_24_P919899 | -0.3803 | 0.3286 | |
| SRP007169 | ATPAF1 | 64756 | RNAseq | -0.5653 | 0.2081 | |
| SRP008496 | ATPAF1 | 64756 | RNAseq | -0.4272 | 0.1097 | |
| SRP064894 | ATPAF1 | 64756 | RNAseq | -0.2595 | 0.0828 | |
| SRP133303 | ATPAF1 | 64756 | RNAseq | -0.1320 | 0.4169 | |
| SRP159526 | ATPAF1 | 64756 | RNAseq | 0.2623 | 0.2995 | |
| SRP193095 | ATPAF1 | 64756 | RNAseq | -0.2199 | 0.0924 | |
| SRP219564 | ATPAF1 | 64756 | RNAseq | -0.3965 | 0.4349 | |
| TCGA | ATPAF1 | 64756 | RNAseq | -0.2295 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATPAF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATPAF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATPAF1 | 64756 | 4 | 3 | 23 | |
| GSE20123 | ATPAF1 | 64756 | 4 | 2 | 24 | |
| GSE43470 | ATPAF1 | 64756 | 5 | 1 | 37 | |
| GSE46452 | ATPAF1 | 64756 | 2 | 1 | 56 | |
| GSE47630 | ATPAF1 | 64756 | 8 | 4 | 28 | |
| GSE54993 | ATPAF1 | 64756 | 0 | 1 | 69 | |
| GSE54994 | ATPAF1 | 64756 | 11 | 2 | 40 | |
| GSE60625 | ATPAF1 | 64756 | 0 | 0 | 11 | |
| GSE74703 | ATPAF1 | 64756 | 4 | 1 | 31 | |
| GSE74704 | ATPAF1 | 64756 | 2 | 0 | 18 | |
| TCGA | ATPAF1 | 64756 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 32; Total Number of normals: 406.
Somatic mutations of ATPAF1:
Generating mutation plots.
Highly correlated genes for ATPAF1:
Showing top 20/36 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATPAF1 | HECTD2 | 0.720383 | 4 | 0 | 4 |
| ATPAF1 | SYF2 | 0.680061 | 3 | 0 | 3 |
| ATPAF1 | FOXN3 | 0.67402 | 3 | 0 | 3 |
| ATPAF1 | DMAP1 | 0.632721 | 5 | 0 | 4 |
| ATPAF1 | C1orf50 | 0.624268 | 5 | 0 | 3 |
| ATPAF1 | HSPB3 | 0.615261 | 3 | 0 | 3 |
| ATPAF1 | RBM25 | 0.612182 | 3 | 0 | 3 |
| ATPAF1 | ANKS1A | 0.61207 | 6 | 0 | 5 |
| ATPAF1 | ZNF311 | 0.605638 | 3 | 0 | 3 |
| ATPAF1 | MYOM1 | 0.59599 | 3 | 0 | 3 |
| ATPAF1 | ZNF627 | 0.591443 | 4 | 0 | 4 |
| ATPAF1 | PBLD | 0.582425 | 4 | 0 | 3 |
| ATPAF1 | KBTBD12 | 0.581197 | 4 | 0 | 3 |
| ATPAF1 | RAVER2 | 0.577445 | 5 | 0 | 4 |
| ATPAF1 | EFCAB7 | 0.573794 | 5 | 0 | 3 |
| ATPAF1 | GLP2R | 0.565081 | 3 | 0 | 3 |
| ATPAF1 | RYR2 | 0.564411 | 5 | 0 | 4 |
| ATPAF1 | TIMM9 | 0.559178 | 3 | 0 | 3 |
| ATPAF1 | INTS12 | 0.557901 | 3 | 0 | 3 |
| ATPAF1 | TYW3 | 0.556704 | 3 | 0 | 3 |
For details and further investigation, click here
