| Full name: kelch repeat and BTB domain containing 12 | Alias Symbol: FLJ46299 | ||
| Type: protein-coding gene | Cytoband: 3q21.3 | ||
| Entrez ID: 166348 | HGNC ID: HGNC:25731 | Ensembl Gene: ENSG00000187715 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KBTBD12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KBTBD12 | 166348 | 244771_at | -0.2764 | 0.5620 | |
| GSE26886 | KBTBD12 | 166348 | 244771_at | 0.2219 | 0.1503 | |
| GSE45670 | KBTBD12 | 166348 | 244771_at | -0.1259 | 0.2896 | |
| GSE53622 | KBTBD12 | 166348 | 45751 | -1.3961 | 0.0000 | |
| GSE53624 | KBTBD12 | 166348 | 76402 | -0.9571 | 0.0000 | |
| GSE63941 | KBTBD12 | 166348 | 244771_at | -0.0226 | 0.8788 | |
| GSE77861 | KBTBD12 | 166348 | 244771_at | -0.0257 | 0.8095 | |
| GSE97050 | KBTBD12 | 166348 | A_33_P3295029 | -0.9618 | 0.1834 | |
| SRP064894 | KBTBD12 | 166348 | RNAseq | -0.6168 | 0.0179 | |
| SRP133303 | KBTBD12 | 166348 | RNAseq | 0.0235 | 0.9393 | |
| SRP159526 | KBTBD12 | 166348 | RNAseq | 1.3153 | 0.1574 | |
| SRP193095 | KBTBD12 | 166348 | RNAseq | -1.6440 | 0.0002 | |
| TCGA | KBTBD12 | 166348 | RNAseq | -2.8251 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by KBTBD12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KBTBD12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KBTBD12 | 166348 | 17 | 0 | 13 | |
| GSE20123 | KBTBD12 | 166348 | 17 | 0 | 13 | |
| GSE43470 | KBTBD12 | 166348 | 19 | 0 | 24 | |
| GSE46452 | KBTBD12 | 166348 | 14 | 5 | 40 | |
| GSE47630 | KBTBD12 | 166348 | 17 | 4 | 19 | |
| GSE54993 | KBTBD12 | 166348 | 2 | 7 | 61 | |
| GSE54994 | KBTBD12 | 166348 | 31 | 3 | 19 | |
| GSE60625 | KBTBD12 | 166348 | 0 | 6 | 5 | |
| GSE74703 | KBTBD12 | 166348 | 17 | 0 | 19 | |
| GSE74704 | KBTBD12 | 166348 | 13 | 0 | 7 | |
| TCGA | KBTBD12 | 166348 | 56 | 6 | 34 |
Total number of gains: 203; Total number of losses: 31; Total Number of normals: 254.
Somatic mutations of KBTBD12:
Generating mutation plots.
Highly correlated genes for KBTBD12:
Showing top 20/314 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KBTBD12 | NPY | 0.813161 | 3 | 0 | 3 |
| KBTBD12 | ITGB1BP2 | 0.782289 | 3 | 0 | 3 |
| KBTBD12 | MYOM1 | 0.755268 | 5 | 0 | 4 |
| KBTBD12 | CAP2 | 0.753843 | 3 | 0 | 3 |
| KBTBD12 | PPP1R14A | 0.751498 | 4 | 0 | 4 |
| KBTBD12 | ADAMTSL3 | 0.746068 | 4 | 0 | 4 |
| KBTBD12 | LRRTM1 | 0.742018 | 5 | 0 | 5 |
| KBTBD12 | GKAP1 | 0.739789 | 4 | 0 | 4 |
| KBTBD12 | SLC25A4 | 0.733292 | 5 | 0 | 5 |
| KBTBD12 | C2orf73 | 0.711525 | 3 | 0 | 3 |
| KBTBD12 | RPS6KL1 | 0.709431 | 3 | 0 | 3 |
| KBTBD12 | SMPX | 0.706589 | 6 | 0 | 5 |
| KBTBD12 | ACTN2 | 0.704553 | 3 | 0 | 3 |
| KBTBD12 | SLC2A4 | 0.695015 | 3 | 0 | 3 |
| KBTBD12 | MRVI1 | 0.693594 | 3 | 0 | 3 |
| KBTBD12 | DENND2A | 0.693199 | 4 | 0 | 3 |
| KBTBD12 | LDB3 | 0.692743 | 3 | 0 | 3 |
| KBTBD12 | PIP5K1C | 0.690971 | 3 | 0 | 3 |
| KBTBD12 | BTC | 0.690038 | 4 | 0 | 3 |
| KBTBD12 | HSPB2 | 0.68994 | 4 | 0 | 3 |
For details and further investigation, click here
