| Full name: SYF2 pre-mRNA splicing factor | Alias Symbol: p29|DKFZp564O2082|NTC31|fSAP29 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 25949 | HGNC ID: HGNC:19824 | Ensembl Gene: ENSG00000117614 | OMIM ID: 607090 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SYF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYF2 | 25949 | 202553_s_at | -0.0426 | 0.9474 | |
| GSE20347 | SYF2 | 25949 | 202553_s_at | -0.0789 | 0.4685 | |
| GSE23400 | SYF2 | 25949 | 202553_s_at | -0.0218 | 0.6969 | |
| GSE26886 | SYF2 | 25949 | 202553_s_at | 0.4797 | 0.0027 | |
| GSE29001 | SYF2 | 25949 | 202553_s_at | -0.0070 | 0.9838 | |
| GSE38129 | SYF2 | 25949 | 202553_s_at | -0.2016 | 0.0182 | |
| GSE45670 | SYF2 | 25949 | 202553_s_at | -0.3111 | 0.0007 | |
| GSE63941 | SYF2 | 25949 | 202553_s_at | -0.3224 | 0.2657 | |
| GSE77861 | SYF2 | 25949 | 202553_s_at | -0.2274 | 0.1414 | |
| GSE97050 | SYF2 | 25949 | A_33_P3264272 | -0.1507 | 0.6594 | |
| SRP007169 | SYF2 | 25949 | RNAseq | 0.0208 | 0.9625 | |
| SRP008496 | SYF2 | 25949 | RNAseq | 0.2137 | 0.4884 | |
| SRP064894 | SYF2 | 25949 | RNAseq | -0.0551 | 0.6949 | |
| SRP133303 | SYF2 | 25949 | RNAseq | -0.1143 | 0.4390 | |
| SRP159526 | SYF2 | 25949 | RNAseq | -0.2170 | 0.3179 | |
| SRP193095 | SYF2 | 25949 | RNAseq | -0.4116 | 0.0008 | |
| SRP219564 | SYF2 | 25949 | RNAseq | -0.4395 | 0.0954 | |
| TCGA | SYF2 | 25949 | RNAseq | -0.0533 | 0.2745 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SYF2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SYF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYF2 | 25949 | 0 | 5 | 25 | |
| GSE20123 | SYF2 | 25949 | 0 | 4 | 26 | |
| GSE43470 | SYF2 | 25949 | 2 | 6 | 35 | |
| GSE46452 | SYF2 | 25949 | 5 | 1 | 53 | |
| GSE47630 | SYF2 | 25949 | 8 | 3 | 29 | |
| GSE54993 | SYF2 | 25949 | 2 | 1 | 67 | |
| GSE54994 | SYF2 | 25949 | 11 | 4 | 38 | |
| GSE60625 | SYF2 | 25949 | 0 | 0 | 11 | |
| GSE74703 | SYF2 | 25949 | 1 | 4 | 31 | |
| GSE74704 | SYF2 | 25949 | 0 | 0 | 20 | |
| TCGA | SYF2 | 25949 | 10 | 24 | 62 |
Total number of gains: 39; Total number of losses: 52; Total Number of normals: 397.
Somatic mutations of SYF2:
Generating mutation plots.
Highly correlated genes for SYF2:
Showing top 20/167 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYF2 | PEX11A | 0.684519 | 3 | 0 | 3 |
| SYF2 | ATPAF1 | 0.680061 | 3 | 0 | 3 |
| SYF2 | ZNF627 | 0.664698 | 4 | 0 | 3 |
| SYF2 | FMR1 | 0.658747 | 3 | 0 | 3 |
| SYF2 | IL15 | 0.655872 | 3 | 0 | 3 |
| SYF2 | ZNF599 | 0.650333 | 3 | 0 | 3 |
| SYF2 | THAP4 | 0.647935 | 3 | 0 | 3 |
| SYF2 | USP48 | 0.64767 | 4 | 0 | 4 |
| SYF2 | MAPKAPK5-AS1 | 0.646001 | 3 | 0 | 3 |
| SYF2 | COX14 | 0.642427 | 3 | 0 | 3 |
| SYF2 | PLEKHS1 | 0.640671 | 3 | 0 | 3 |
| SYF2 | DENND4A | 0.637659 | 4 | 0 | 4 |
| SYF2 | DYNC2LI1 | 0.634051 | 4 | 0 | 4 |
| SYF2 | PDE6D | 0.629407 | 3 | 0 | 3 |
| SYF2 | LARP7 | 0.628737 | 5 | 0 | 4 |
| SYF2 | PIGK | 0.62183 | 3 | 0 | 3 |
| SYF2 | RPL7 | 0.621754 | 4 | 0 | 4 |
| SYF2 | NEGR1 | 0.616523 | 3 | 0 | 3 |
| SYF2 | PCF11 | 0.612135 | 4 | 0 | 4 |
| SYF2 | INTS12 | 0.61148 | 4 | 0 | 4 |
For details and further investigation, click here
