| Full name: forkhead box N3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q31.3-q32.11 | ||
| Entrez ID: 1112 | HGNC ID: HGNC:1928 | Ensembl Gene: ENSG00000053254 | OMIM ID: 602628 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FOXN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXN3 | 1112 | 222494_at | -0.4928 | 0.3468 | |
| GSE20347 | FOXN3 | 1112 | 218031_s_at | -0.7561 | 0.0014 | |
| GSE23400 | FOXN3 | 1112 | 218031_s_at | -0.3500 | 0.0033 | |
| GSE26886 | FOXN3 | 1112 | 205022_s_at | 1.1357 | 0.0000 | |
| GSE29001 | FOXN3 | 1112 | 205022_s_at | -0.0130 | 0.9682 | |
| GSE38129 | FOXN3 | 1112 | 205022_s_at | -0.6518 | 0.0007 | |
| GSE45670 | FOXN3 | 1112 | 205022_s_at | -0.4293 | 0.0154 | |
| GSE63941 | FOXN3 | 1112 | 222494_at | -2.3257 | 0.0027 | |
| GSE77861 | FOXN3 | 1112 | 222494_at | -0.1390 | 0.6881 | |
| GSE97050 | FOXN3 | 1112 | A_23_P88435 | -0.6137 | 0.1783 | |
| SRP007169 | FOXN3 | 1112 | RNAseq | -0.6783 | 0.0400 | |
| SRP008496 | FOXN3 | 1112 | RNAseq | -0.4038 | 0.0545 | |
| SRP064894 | FOXN3 | 1112 | RNAseq | -0.3024 | 0.1829 | |
| SRP133303 | FOXN3 | 1112 | RNAseq | -0.1224 | 0.4745 | |
| SRP159526 | FOXN3 | 1112 | RNAseq | -0.5853 | 0.1089 | |
| SRP193095 | FOXN3 | 1112 | RNAseq | -0.3597 | 0.0001 | |
| SRP219564 | FOXN3 | 1112 | RNAseq | -0.3127 | 0.5056 | |
| TCGA | FOXN3 | 1112 | RNAseq | -0.3035 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by FOXN3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FOXN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXN3 | 1112 | 8 | 5 | 17 | |
| GSE20123 | FOXN3 | 1112 | 8 | 5 | 17 | |
| GSE43470 | FOXN3 | 1112 | 7 | 3 | 33 | |
| GSE46452 | FOXN3 | 1112 | 16 | 3 | 40 | |
| GSE47630 | FOXN3 | 1112 | 11 | 8 | 21 | |
| GSE54993 | FOXN3 | 1112 | 3 | 8 | 59 | |
| GSE54994 | FOXN3 | 1112 | 19 | 4 | 30 | |
| GSE60625 | FOXN3 | 1112 | 0 | 2 | 9 | |
| GSE74703 | FOXN3 | 1112 | 6 | 3 | 27 | |
| GSE74704 | FOXN3 | 1112 | 4 | 4 | 12 | |
| TCGA | FOXN3 | 1112 | 31 | 21 | 44 |
Total number of gains: 113; Total number of losses: 66; Total Number of normals: 309.
Somatic mutations of FOXN3:
Generating mutation plots.
Highly correlated genes for FOXN3:
Showing top 20/790 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXN3 | ANO6 | 0.860046 | 3 | 0 | 3 |
| FOXN3 | RASSF3 | 0.856661 | 3 | 0 | 3 |
| FOXN3 | PRICKLE2 | 0.833079 | 3 | 0 | 3 |
| FOXN3 | DEGS1 | 0.827314 | 3 | 0 | 3 |
| FOXN3 | PARD3B | 0.824255 | 3 | 0 | 3 |
| FOXN3 | THRB | 0.80071 | 3 | 0 | 3 |
| FOXN3 | CMC4 | 0.784937 | 3 | 0 | 3 |
| FOXN3 | PPM1L | 0.778498 | 3 | 0 | 3 |
| FOXN3 | FOXP2 | 0.774435 | 3 | 0 | 3 |
| FOXN3 | DZIP1L | 0.763686 | 3 | 0 | 3 |
| FOXN3 | PCBD2 | 0.759973 | 3 | 0 | 3 |
| FOXN3 | ATP2B4 | 0.758893 | 3 | 0 | 3 |
| FOXN3 | FNIP1 | 0.757314 | 3 | 0 | 3 |
| FOXN3 | CD164 | 0.756416 | 3 | 0 | 3 |
| FOXN3 | SGMS1 | 0.75446 | 3 | 0 | 3 |
| FOXN3 | ZNF10 | 0.753718 | 3 | 0 | 3 |
| FOXN3 | ANTXR2 | 0.751501 | 4 | 0 | 4 |
| FOXN3 | AP1S2 | 0.751356 | 4 | 0 | 3 |
| FOXN3 | BAG5 | 0.751023 | 3 | 0 | 3 |
| FOXN3 | PSEN1 | 0.748622 | 3 | 0 | 3 |
For details and further investigation, click here
