PBLD

 

Full name: phenazine biosynthesis like protein domain containing Alias Symbol: MAWBP|MAWDBP|FLJ14767
Type: protein-coding gene Cytoband: 10q21.3
Entrez ID: 64081 HGNC ID: HGNC:23301 Ensembl Gene: ENSG00000108187 OMIM ID: 612189
Drug and gene relationship at DGIdb

 

Expression of PBLD:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PBLD 64081 219543_at -0.2829 0.6806
GSE20347 PBLD 64081 219543_at 0.0382 0.8371
GSE23400 PBLD 64081 219543_at -0.0159 0.6983
GSE26886 PBLD 64081 219543_at 0.7037 0.0089
GSE29001 PBLD 64081 219543_at 0.5336 0.0583
GSE38129 PBLD 64081 219543_at -0.4410 0.1108
GSE45670 PBLD 64081 219543_at -0.6316 0.0086
GSE53622 PBLD 64081 92184 -0.4350 0.0068
GSE53624 PBLD 64081 92184 -0.0625 0.4886
GSE63941 PBLD 64081 219543_at -1.9945 0.0229
GSE77861 PBLD 64081 1555175_a_at -0.0887 0.3686
GSE97050 PBLD 64081 A_24_P312519 -0.6342 0.2682
SRP007169 PBLD 64081 RNAseq -0.1140 0.8410
SRP064894 PBLD 64081 RNAseq 0.0865 0.6759
SRP133303 PBLD 64081 RNAseq 0.1597 0.3093
SRP159526 PBLD 64081 RNAseq -0.0412 0.9108
SRP193095 PBLD 64081 RNAseq -0.6418 0.1286
SRP219564 PBLD 64081 RNAseq -0.2381 0.5379
TCGA PBLD 64081 RNAseq -1.2753 0.0000

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by PBLD expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PBLD:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PBLD 64081 3 5 22
GSE20123 PBLD 64081 3 4 23
GSE43470 PBLD 64081 1 8 34
GSE46452 PBLD 64081 0 11 48
GSE47630 PBLD 64081 2 14 24
GSE54993 PBLD 64081 8 0 62
GSE54994 PBLD 64081 2 12 39
GSE60625 PBLD 64081 0 0 11
GSE74703 PBLD 64081 1 5 30
GSE74704 PBLD 64081 1 3 16
TCGA PBLD 64081 10 22 64

Total number of gains: 31; Total number of losses: 84; Total Number of normals: 373.  


 

Somatic mutations of PBLD:

 

Generating mutation plots.

 

Highly correlated genes for PBLD:

 

Showing top 20/447 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PBLDAFF30.755906303
PBLDRGMB0.713849404
PBLDCBLL10.693599303
PBLDEDNRB0.68418606
PBLDCAMK2N10.679531303
PBLDC1QTNF70.676069503
PBLDPGR0.675017404
PBLDCYP4V20.671251404
PBLDZMAT40.668539303
PBLDMAP90.668249504
PBLDSYNC0.667611605
PBLDESRRG0.667537504
PBLDFGL20.667079806
PBLDNES0.665795404
PBLDZXDA0.665099303
PBLDZNF3470.66448403
PBLDSNTB10.663494504
PBLDZNF8800.66249404
PBLDPEG100.659751303
PBLDC16orf860.657672403

For details and further investigation, click here