| Full name: ankyrin repeat and sterile alpha motif domain containing 1A | Alias Symbol: KIAA0229 | ||
| Type: protein-coding gene | Cytoband: 6p21.31 | ||
| Entrez ID: 23294 | HGNC ID: HGNC:20961 | Ensembl Gene: ENSG00000064999 | OMIM ID: 608994 |
| Drug and gene relationship at DGIdb | |||
Expression of ANKS1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKS1A | 23294 | 212747_at | -0.0073 | 0.9949 | |
| GSE20347 | ANKS1A | 23294 | 212747_at | 0.1067 | 0.5326 | |
| GSE23400 | ANKS1A | 23294 | 212747_at | -0.1644 | 0.0752 | |
| GSE26886 | ANKS1A | 23294 | 212747_at | 0.2988 | 0.0896 | |
| GSE29001 | ANKS1A | 23294 | 212747_at | 0.3510 | 0.0286 | |
| GSE38129 | ANKS1A | 23294 | 212747_at | -0.2095 | 0.3211 | |
| GSE45670 | ANKS1A | 23294 | 212747_at | -0.0834 | 0.5965 | |
| GSE53622 | ANKS1A | 23294 | 67408 | -0.3146 | 0.0013 | |
| GSE53624 | ANKS1A | 23294 | 67408 | -0.1313 | 0.0517 | |
| GSE63941 | ANKS1A | 23294 | 212747_at | 0.1762 | 0.4892 | |
| GSE77861 | ANKS1A | 23294 | 212747_at | 0.0243 | 0.9355 | |
| GSE97050 | ANKS1A | 23294 | A_23_P156748 | -0.6520 | 0.2083 | |
| SRP007169 | ANKS1A | 23294 | RNAseq | 0.7902 | 0.0697 | |
| SRP008496 | ANKS1A | 23294 | RNAseq | 0.6409 | 0.0231 | |
| SRP064894 | ANKS1A | 23294 | RNAseq | -0.0195 | 0.9098 | |
| SRP133303 | ANKS1A | 23294 | RNAseq | -0.1390 | 0.4972 | |
| SRP159526 | ANKS1A | 23294 | RNAseq | -0.3099 | 0.1809 | |
| SRP193095 | ANKS1A | 23294 | RNAseq | 0.1084 | 0.2141 | |
| SRP219564 | ANKS1A | 23294 | RNAseq | -0.1915 | 0.7778 | |
| TCGA | ANKS1A | 23294 | RNAseq | -0.1683 | 0.0021 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANKS1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKS1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKS1A | 23294 | 5 | 0 | 25 | |
| GSE20123 | ANKS1A | 23294 | 5 | 0 | 25 | |
| GSE43470 | ANKS1A | 23294 | 5 | 1 | 37 | |
| GSE46452 | ANKS1A | 23294 | 2 | 9 | 48 | |
| GSE47630 | ANKS1A | 23294 | 8 | 4 | 28 | |
| GSE54993 | ANKS1A | 23294 | 3 | 1 | 66 | |
| GSE54994 | ANKS1A | 23294 | 11 | 4 | 38 | |
| GSE60625 | ANKS1A | 23294 | 1 | 0 | 10 | |
| GSE74703 | ANKS1A | 23294 | 5 | 0 | 31 | |
| GSE74704 | ANKS1A | 23294 | 2 | 0 | 18 | |
| TCGA | ANKS1A | 23294 | 17 | 16 | 63 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of ANKS1A:
Generating mutation plots.
Highly correlated genes for ANKS1A:
Showing top 20/393 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKS1A | CADM2 | 0.800103 | 3 | 0 | 3 |
| ANKS1A | OTOGL | 0.748815 | 3 | 0 | 3 |
| ANKS1A | AMIGO1 | 0.747401 | 3 | 0 | 3 |
| ANKS1A | EPM2A | 0.730365 | 5 | 0 | 4 |
| ANKS1A | HINT2 | 0.727886 | 3 | 0 | 3 |
| ANKS1A | MITF | 0.72661 | 5 | 0 | 5 |
| ANKS1A | PNCK | 0.715561 | 3 | 0 | 3 |
| ANKS1A | HAND2-AS1 | 0.714692 | 4 | 0 | 4 |
| ANKS1A | HAND2 | 0.710692 | 3 | 0 | 3 |
| ANKS1A | CCDC69 | 0.706224 | 5 | 0 | 5 |
| ANKS1A | LIMS2 | 0.700887 | 6 | 0 | 6 |
| ANKS1A | KLHL30 | 0.699548 | 3 | 0 | 3 |
| ANKS1A | SLC12A2 | 0.688701 | 3 | 0 | 3 |
| ANKS1A | PLEKHO1 | 0.687653 | 8 | 0 | 8 |
| ANKS1A | ASB2 | 0.68413 | 4 | 0 | 4 |
| ANKS1A | STK33 | 0.67408 | 3 | 0 | 3 |
| ANKS1A | TPM2 | 0.673573 | 7 | 0 | 6 |
| ANKS1A | DDX42 | 0.672703 | 4 | 0 | 3 |
| ANKS1A | PPARGC1A | 0.66966 | 5 | 0 | 5 |
| ANKS1A | GPM6A | 0.667532 | 7 | 0 | 6 |
For details and further investigation, click here
