RBM25

 

Full name: RNA binding motif protein 25 Alias Symbol: S164|fSAP94|NET52|Snu71
Type: protein-coding gene Cytoband: 14q24.2
Entrez ID: 58517 HGNC ID: HGNC:23244 Ensembl Gene: ENSG00000119707 OMIM ID: 612427
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of RBM25:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RBM25 58517 212033_at 0.2500 0.6401
GSE20347 RBM25 58517 212033_at 0.1492 0.2819
GSE23400 RBM25 58517 212033_at 0.2439 0.0009
GSE26886 RBM25 58517 212027_at 0.8402 0.0310
GSE29001 RBM25 58517 212031_at 0.2303 0.3479
GSE38129 RBM25 58517 212033_at 0.0987 0.3648
GSE45670 RBM25 58517 212033_at -0.0366 0.8053
GSE53622 RBM25 58517 92800 0.1515 0.0021
GSE53624 RBM25 58517 92800 0.0377 0.4351
GSE63941 RBM25 58517 212033_at -0.7099 0.0996
GSE77861 RBM25 58517 212033_at -0.0903 0.7964
GSE97050 RBM25 58517 A_23_P99762 -0.0076 0.9783
SRP007169 RBM25 58517 RNAseq 0.7124 0.1022
SRP008496 RBM25 58517 RNAseq 0.7491 0.0095
SRP064894 RBM25 58517 RNAseq -0.0238 0.9058
SRP133303 RBM25 58517 RNAseq 0.0389 0.7385
SRP159526 RBM25 58517 RNAseq -0.2194 0.3950
SRP193095 RBM25 58517 RNAseq 0.0265 0.7971
SRP219564 RBM25 58517 RNAseq 0.0461 0.8755
TCGA RBM25 58517 RNAseq -0.0475 0.2461

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by RBM25 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RBM25:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RBM25 58517 8 2 20
GSE20123 RBM25 58517 8 2 20
GSE43470 RBM25 58517 8 3 32
GSE46452 RBM25 58517 16 3 40
GSE47630 RBM25 58517 11 8 21
GSE54993 RBM25 58517 3 8 59
GSE54994 RBM25 58517 19 4 30
GSE60625 RBM25 58517 0 2 9
GSE74703 RBM25 58517 7 3 26
GSE74704 RBM25 58517 3 2 15
TCGA RBM25 58517 31 17 48

Total number of gains: 114; Total number of losses: 54; Total Number of normals: 320.  


 

Somatic mutations of RBM25:

 

Generating mutation plots.

 

Highly correlated genes for RBM25:

 

Showing top 20/64 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RBM25DNAJC160.747914303
RBM25ZNF6780.723992303
RBM25PARS20.680683303
RBM25MDC10.670908303
RBM25C19orf250.670652303
RBM25ANKS30.669199303
RBM25RASL11B0.659909404
RBM25PEX260.655869303
RBM25GPC20.652902303
RBM25CDC42BPB0.652507404
RBM25ATG4D0.642452303
RBM25RAB40B0.625847403
RBM25CLCN60.624776504
RBM25DOHH0.622143403
RBM25BCAT20.621144403
RBM25AP1M10.620755403
RBM25ZNF2050.617131404
RBM25SHARPIN0.616026303
RBM25ATPAF10.612182303
RBM25POMT20.609585503

For details and further investigation, click here