| Full name: leukocyte immunoglobulin like receptor A3 | Alias Symbol: LIR-4|HM43|ILT6|HM31|LIR4|CD85e | ||
| Type: protein-coding gene | Cytoband: 19q13.4 alternate reference locus | ||
| Entrez ID: 11026 | HGNC ID: HGNC:6604 | Ensembl Gene: | OMIM ID: 604818 |
| Drug and gene relationship at DGIdb | |||
LILRA3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04380 | Osteoclast differentiation |
Expression of LILRA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LILRA3 | 11026 | 206881_s_at | 0.0778 | 0.6944 | |
| GSE20347 | LILRA3 | 11026 | 206881_s_at | 0.0020 | 0.9794 | |
| GSE23400 | LILRA3 | 11026 | 206881_s_at | -0.0421 | 0.1512 | |
| GSE26886 | LILRA3 | 11026 | 206881_s_at | 0.4648 | 0.0189 | |
| GSE29001 | LILRA3 | 11026 | 206881_s_at | 0.1202 | 0.4199 | |
| GSE38129 | LILRA3 | 11026 | 206881_s_at | -0.0222 | 0.7704 | |
| GSE45670 | LILRA3 | 11026 | 206881_s_at | 0.0960 | 0.4190 | |
| GSE63941 | LILRA3 | 11026 | 206881_s_at | -0.0319 | 0.8450 | |
| GSE77861 | LILRA3 | 11026 | 206881_s_at | -0.0405 | 0.7970 | |
| GSE97050 | LILRA3 | 11026 | A_23_P79094 | 0.7221 | 0.1695 | |
| TCGA | LILRA3 | 11026 | RNAseq | 2.4096 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LILRA3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LILRA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LILRA3 | 11026 | 3 | 4 | 23 | |
| GSE20123 | LILRA3 | 11026 | 3 | 3 | 24 | |
| GSE43470 | LILRA3 | 11026 | 2 | 11 | 30 | |
| GSE46452 | LILRA3 | 11026 | 45 | 1 | 13 | |
| GSE47630 | LILRA3 | 11026 | 8 | 6 | 26 | |
| GSE54993 | LILRA3 | 11026 | 17 | 4 | 49 | |
| GSE54994 | LILRA3 | 11026 | 4 | 13 | 36 | |
| GSE60625 | LILRA3 | 11026 | 9 | 0 | 2 | |
| GSE74703 | LILRA3 | 11026 | 2 | 7 | 27 | |
| GSE74704 | LILRA3 | 11026 | 3 | 1 | 16 | |
| TCGA | LILRA3 | 11026 | 19 | 15 | 62 |
Total number of gains: 115; Total number of losses: 65; Total Number of normals: 308.
Somatic mutations of LILRA3:
Generating mutation plots.
Highly correlated genes for LILRA3:
Showing top 20/494 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LILRA3 | PVALB | 0.787379 | 3 | 0 | 3 |
| LILRA3 | ACSF3 | 0.742649 | 3 | 0 | 3 |
| LILRA3 | PLD4 | 0.73704 | 3 | 0 | 3 |
| LILRA3 | GINS2 | 0.730852 | 3 | 0 | 3 |
| LILRA3 | GPR150 | 0.715214 | 3 | 0 | 3 |
| LILRA3 | POLE4 | 0.707836 | 3 | 0 | 3 |
| LILRA3 | DMP1 | 0.700086 | 3 | 0 | 3 |
| LILRA3 | LIPG | 0.699535 | 3 | 0 | 3 |
| LILRA3 | TLR9 | 0.69871 | 3 | 0 | 3 |
| LILRA3 | AVPR2 | 0.694846 | 4 | 0 | 4 |
| LILRA3 | C19orf81 | 0.694747 | 3 | 0 | 3 |
| LILRA3 | NAT8B | 0.694568 | 4 | 0 | 4 |
| LILRA3 | CALML6 | 0.691117 | 3 | 0 | 3 |
| LILRA3 | RENBP | 0.690257 | 4 | 0 | 3 |
| LILRA3 | HCRTR1 | 0.688711 | 3 | 0 | 3 |
| LILRA3 | TK1 | 0.68645 | 3 | 0 | 3 |
| LILRA3 | MAP1LC3C | 0.685664 | 3 | 0 | 3 |
| LILRA3 | AGRP | 0.683046 | 4 | 0 | 4 |
| LILRA3 | CIITA | 0.682829 | 3 | 0 | 3 |
| LILRA3 | OR1F1 | 0.679955 | 6 | 0 | 6 |
For details and further investigation, click here
