| Full name: EBF family member 4 | Alias Symbol: KIAA1442|COE4|RP5-860F19.3|O/E-4 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 57593 | HGNC ID: HGNC:29278 | Ensembl Gene: ENSG00000088881 | OMIM ID: 609935 |
| Drug and gene relationship at DGIdb | |||
Expression of EBF4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EBF4 | 57593 | 233850_s_at | 0.0029 | 0.9949 | |
| GSE26886 | EBF4 | 57593 | 233850_s_at | 0.5116 | 0.0005 | |
| GSE45670 | EBF4 | 57593 | 233850_s_at | -0.2155 | 0.0242 | |
| GSE53622 | EBF4 | 57593 | 29961 | 0.4550 | 0.0001 | |
| GSE53624 | EBF4 | 57593 | 29961 | 0.3297 | 0.0000 | |
| GSE63941 | EBF4 | 57593 | 233850_s_at | 0.0586 | 0.8059 | |
| GSE77861 | EBF4 | 57593 | 233850_s_at | -0.2123 | 0.1336 | |
| GSE97050 | EBF4 | 57593 | A_33_P3209537 | 0.1494 | 0.6908 | |
| SRP064894 | EBF4 | 57593 | RNAseq | 0.6876 | 0.0546 | |
| SRP133303 | EBF4 | 57593 | RNAseq | 0.6466 | 0.0269 | |
| SRP159526 | EBF4 | 57593 | RNAseq | 0.7950 | 0.0514 | |
| SRP193095 | EBF4 | 57593 | RNAseq | 0.8352 | 0.0000 | |
| SRP219564 | EBF4 | 57593 | RNAseq | 0.9303 | 0.2502 | |
| TCGA | EBF4 | 57593 | RNAseq | -0.1637 | 0.2605 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EBF4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EBF4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EBF4 | 57593 | 12 | 3 | 15 | |
| GSE20123 | EBF4 | 57593 | 13 | 3 | 14 | |
| GSE43470 | EBF4 | 57593 | 10 | 1 | 32 | |
| GSE46452 | EBF4 | 57593 | 26 | 1 | 32 | |
| GSE47630 | EBF4 | 57593 | 18 | 4 | 18 | |
| GSE54993 | EBF4 | 57593 | 2 | 14 | 54 | |
| GSE54994 | EBF4 | 57593 | 24 | 2 | 27 | |
| GSE60625 | EBF4 | 57593 | 0 | 0 | 11 | |
| GSE74703 | EBF4 | 57593 | 9 | 1 | 26 | |
| GSE74704 | EBF4 | 57593 | 8 | 1 | 11 | |
| TCGA | EBF4 | 57593 | 40 | 11 | 45 |
Total number of gains: 162; Total number of losses: 41; Total Number of normals: 285.
Somatic mutations of EBF4:
Generating mutation plots.
Highly correlated genes for EBF4:
Showing top 20/345 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EBF4 | SCARF2 | 0.773982 | 3 | 0 | 3 |
| EBF4 | SHISA4 | 0.752219 | 3 | 0 | 3 |
| EBF4 | AVPR2 | 0.742593 | 3 | 0 | 3 |
| EBF4 | IGSF21 | 0.736376 | 3 | 0 | 3 |
| EBF4 | CHST10 | 0.730513 | 4 | 0 | 4 |
| EBF4 | SLC25A47 | 0.72862 | 3 | 0 | 3 |
| EBF4 | DLK1 | 0.721851 | 4 | 0 | 4 |
| EBF4 | IQSEC3 | 0.720393 | 3 | 0 | 3 |
| EBF4 | GNL1 | 0.719773 | 4 | 0 | 3 |
| EBF4 | DPEP1 | 0.699839 | 3 | 0 | 3 |
| EBF4 | CLCNKB | 0.698896 | 4 | 0 | 4 |
| EBF4 | PPP1R12C | 0.696815 | 4 | 0 | 4 |
| EBF4 | GAL3ST1 | 0.692748 | 3 | 0 | 3 |
| EBF4 | MRGPRG | 0.691865 | 3 | 0 | 3 |
| EBF4 | TNFRSF14 | 0.687316 | 4 | 0 | 4 |
| EBF4 | NOXA1 | 0.683906 | 5 | 0 | 4 |
| EBF4 | RIMS4 | 0.679195 | 4 | 0 | 4 |
| EBF4 | RANBP3 | 0.677717 | 3 | 0 | 3 |
| EBF4 | C2CD4D | 0.675215 | 3 | 0 | 3 |
| EBF4 | GGTLC1 | 0.675088 | 3 | 0 | 3 |
For details and further investigation, click here
