| Full name: poly(ADP-ribose) polymerase family member 11 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12p13.32 | ||
| Entrez ID: 57097 | HGNC ID: HGNC:1186 | Ensembl Gene: ENSG00000111224 | OMIM ID: 616706 |
| Drug and gene relationship at DGIdb | |||
Expression of PARP11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PARP11 | 57097 | 229138_at | -0.0814 | 0.8271 | |
| GSE20347 | PARP11 | 57097 | 220315_at | 0.0544 | 0.6293 | |
| GSE23400 | PARP11 | 57097 | 220315_at | -0.0771 | 0.0180 | |
| GSE26886 | PARP11 | 57097 | 229138_at | -0.3262 | 0.5700 | |
| GSE29001 | PARP11 | 57097 | 220315_at | 0.2345 | 0.2377 | |
| GSE38129 | PARP11 | 57097 | 220315_at | 0.0280 | 0.7927 | |
| GSE45670 | PARP11 | 57097 | 229138_at | 0.2026 | 0.2120 | |
| GSE53622 | PARP11 | 57097 | 41273 | -0.0147 | 0.8966 | |
| GSE53624 | PARP11 | 57097 | 41273 | 0.1265 | 0.3387 | |
| GSE63941 | PARP11 | 57097 | 229138_at | -1.5922 | 0.0826 | |
| GSE77861 | PARP11 | 57097 | 1554116_s_at | -0.0490 | 0.7117 | |
| GSE97050 | PARP11 | 57097 | A_23_P343837 | 0.0485 | 0.8443 | |
| SRP007169 | PARP11 | 57097 | RNAseq | 0.5176 | 0.1217 | |
| SRP008496 | PARP11 | 57097 | RNAseq | 0.6050 | 0.0080 | |
| SRP064894 | PARP11 | 57097 | RNAseq | -0.1350 | 0.3568 | |
| SRP133303 | PARP11 | 57097 | RNAseq | 0.3326 | 0.0855 | |
| SRP159526 | PARP11 | 57097 | RNAseq | 0.1201 | 0.6575 | |
| SRP193095 | PARP11 | 57097 | RNAseq | -0.0437 | 0.7266 | |
| SRP219564 | PARP11 | 57097 | RNAseq | 0.7553 | 0.0017 | |
| TCGA | PARP11 | 57097 | RNAseq | 0.1249 | 0.1881 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PARP11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PARP11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PARP11 | 57097 | 6 | 4 | 20 | |
| GSE20123 | PARP11 | 57097 | 6 | 4 | 20 | |
| GSE43470 | PARP11 | 57097 | 10 | 3 | 30 | |
| GSE46452 | PARP11 | 57097 | 10 | 1 | 48 | |
| GSE47630 | PARP11 | 57097 | 12 | 2 | 26 | |
| GSE54993 | PARP11 | 57097 | 1 | 10 | 59 | |
| GSE54994 | PARP11 | 57097 | 10 | 2 | 41 | |
| GSE60625 | PARP11 | 57097 | 0 | 1 | 10 | |
| GSE74703 | PARP11 | 57097 | 9 | 2 | 25 | |
| GSE74704 | PARP11 | 57097 | 4 | 2 | 14 | |
| TCGA | PARP11 | 57097 | 41 | 6 | 49 |
Total number of gains: 109; Total number of losses: 37; Total Number of normals: 342.
Somatic mutations of PARP11:
Generating mutation plots.
Highly correlated genes for PARP11:
Showing top 20/132 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PARP11 | ZNF623 | 0.72397 | 3 | 0 | 3 |
| PARP11 | ZNF784 | 0.710303 | 3 | 0 | 3 |
| PARP11 | BIVM | 0.694763 | 3 | 0 | 3 |
| PARP11 | LAX1 | 0.692573 | 3 | 0 | 3 |
| PARP11 | ARL6 | 0.685804 | 3 | 0 | 3 |
| PARP11 | TMEM44 | 0.682649 | 3 | 0 | 3 |
| PARP11 | SH3BP5 | 0.678166 | 3 | 0 | 3 |
| PARP11 | TMSB15B | 0.673588 | 3 | 0 | 3 |
| PARP11 | KPNA5 | 0.67209 | 4 | 0 | 3 |
| PARP11 | APOL3 | 0.666928 | 3 | 0 | 3 |
| PARP11 | SALL2 | 0.661893 | 3 | 0 | 3 |
| PARP11 | PEX2 | 0.657346 | 4 | 0 | 4 |
| PARP11 | TCF12 | 0.656026 | 3 | 0 | 3 |
| PARP11 | TNFRSF19 | 0.65524 | 3 | 0 | 3 |
| PARP11 | ERCC3 | 0.649766 | 3 | 0 | 3 |
| PARP11 | RARS2 | 0.648498 | 3 | 0 | 3 |
| PARP11 | DCP2 | 0.647957 | 4 | 0 | 3 |
| PARP11 | MCPH1 | 0.646305 | 3 | 0 | 3 |
| PARP11 | B3GALNT1 | 0.645705 | 3 | 0 | 3 |
| PARP11 | B3GALT2 | 0.638965 | 4 | 0 | 3 |
For details and further investigation, click here
