| Full name: leucine rich repeat containing 34 | Alias Symbol: MGC27085 | ||
| Type: protein-coding gene | Cytoband: 3q26.2 | ||
| Entrez ID: 151827 | HGNC ID: HGNC:28408 | Ensembl Gene: ENSG00000171757 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC34 | 151827 | 236918_s_at | 0.3812 | 0.6348 | |
| GSE26886 | LRRC34 | 151827 | 236918_s_at | 0.6013 | 0.0733 | |
| GSE45670 | LRRC34 | 151827 | 236918_s_at | -0.1708 | 0.6954 | |
| GSE63941 | LRRC34 | 151827 | 236918_s_at | -1.7863 | 0.0513 | |
| GSE77861 | LRRC34 | 151827 | 236918_s_at | 0.1835 | 0.2138 | |
| GSE97050 | LRRC34 | A_21_P0000091 | 0.2470 | 0.5563 | ||
| SRP007169 | LRRC34 | 151827 | RNAseq | 2.2868 | 0.0139 | |
| SRP064894 | LRRC34 | 151827 | RNAseq | 0.4242 | 0.1587 | |
| SRP133303 | LRRC34 | 151827 | RNAseq | 0.2041 | 0.4137 | |
| SRP159526 | LRRC34 | 151827 | RNAseq | 0.4835 | 0.3223 | |
| SRP193095 | LRRC34 | 151827 | RNAseq | 0.5143 | 0.0002 | |
| SRP219564 | LRRC34 | 151827 | RNAseq | -0.3678 | 0.4186 | |
| TCGA | LRRC34 | 151827 | RNAseq | -0.0684 | 0.7051 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LRRC34 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LRRC34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC34 | 151827 | 22 | 0 | 8 | |
| GSE20123 | LRRC34 | 151827 | 22 | 0 | 8 | |
| GSE43470 | LRRC34 | 151827 | 24 | 0 | 19 | |
| GSE46452 | LRRC34 | 151827 | 19 | 1 | 39 | |
| GSE47630 | LRRC34 | 151827 | 27 | 2 | 11 | |
| GSE54993 | LRRC34 | 151827 | 1 | 14 | 55 | |
| GSE54994 | LRRC34 | 151827 | 41 | 0 | 12 | |
| GSE60625 | LRRC34 | 151827 | 0 | 6 | 5 | |
| GSE74703 | LRRC34 | 151827 | 20 | 0 | 16 | |
| GSE74704 | LRRC34 | 151827 | 14 | 0 | 6 | |
| TCGA | LRRC34 | 151827 | 80 | 0 | 16 |
Total number of gains: 270; Total number of losses: 23; Total Number of normals: 195.
Somatic mutations of LRRC34:
Generating mutation plots.
Highly correlated genes for LRRC34:
Showing top 20/396 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC34 | ZSCAN29 | 0.800379 | 3 | 0 | 3 |
| LRRC34 | IFT20 | 0.792723 | 3 | 0 | 3 |
| LRRC34 | ANKIB1 | 0.791885 | 3 | 0 | 3 |
| LRRC34 | TBRG4 | 0.787051 | 3 | 0 | 3 |
| LRRC34 | THAP5 | 0.773913 | 3 | 0 | 3 |
| LRRC34 | USP34 | 0.772943 | 3 | 0 | 3 |
| LRRC34 | ZNF578 | 0.770656 | 3 | 0 | 3 |
| LRRC34 | KIAA2013 | 0.769192 | 3 | 0 | 3 |
| LRRC34 | TNFRSF10D | 0.766922 | 3 | 0 | 3 |
| LRRC34 | CTBP2 | 0.766721 | 3 | 0 | 3 |
| LRRC34 | SRSF6 | 0.765509 | 3 | 0 | 3 |
| LRRC34 | LRRC47 | 0.765393 | 3 | 0 | 3 |
| LRRC34 | ETV6 | 0.765044 | 3 | 0 | 3 |
| LRRC34 | ASTE1 | 0.763388 | 3 | 0 | 3 |
| LRRC34 | SENP1 | 0.758824 | 3 | 0 | 3 |
| LRRC34 | GPX7 | 0.756839 | 4 | 0 | 4 |
| LRRC34 | DTX4 | 0.756577 | 3 | 0 | 3 |
| LRRC34 | CHAF1B | 0.755915 | 3 | 0 | 3 |
| LRRC34 | MCAM | 0.753836 | 3 | 0 | 3 |
| LRRC34 | SMC3 | 0.753798 | 3 | 0 | 3 |
For details and further investigation, click here
