| Full name: zinc finger protein 436 | Alias Symbol: KIAA1710|Zfp46 | ||
| Type: protein-coding gene | Cytoband: 1p36.12 | ||
| Entrez ID: 80818 | HGNC ID: HGNC:20814 | Ensembl Gene: ENSG00000125945 | OMIM ID: 611703 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF436:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF436 | 80818 | 226113_at | -0.1920 | 0.8543 | |
| GSE26886 | ZNF436 | 80818 | 226113_at | -0.9280 | 0.0014 | |
| GSE45670 | ZNF436 | 80818 | 226113_at | -0.5792 | 0.0024 | |
| GSE53622 | ZNF436 | 80818 | 99794 | -0.2518 | 0.0080 | |
| GSE53624 | ZNF436 | 80818 | 99794 | -0.3067 | 0.0000 | |
| GSE63941 | ZNF436 | 80818 | 226113_at | 0.2106 | 0.7724 | |
| GSE77861 | ZNF436 | 80818 | 226113_at | -0.8043 | 0.0007 | |
| GSE97050 | ZNF436 | 80818 | A_23_P51202 | -0.1291 | 0.6803 | |
| SRP007169 | ZNF436 | 80818 | RNAseq | -0.6603 | 0.1362 | |
| SRP008496 | ZNF436 | 80818 | RNAseq | -0.6597 | 0.0240 | |
| SRP064894 | ZNF436 | 80818 | RNAseq | -0.4417 | 0.0501 | |
| SRP133303 | ZNF436 | 80818 | RNAseq | -0.4894 | 0.0116 | |
| SRP159526 | ZNF436 | 80818 | RNAseq | -0.6628 | 0.0299 | |
| SRP193095 | ZNF436 | 80818 | RNAseq | -0.7463 | 0.0000 | |
| SRP219564 | ZNF436 | 80818 | RNAseq | -0.8462 | 0.0043 | |
| TCGA | ZNF436 | 80818 | RNAseq | 0.0893 | 0.1433 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF436 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF436:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF436 | 80818 | 0 | 5 | 25 | |
| GSE20123 | ZNF436 | 80818 | 0 | 4 | 26 | |
| GSE43470 | ZNF436 | 80818 | 2 | 6 | 35 | |
| GSE46452 | ZNF436 | 80818 | 5 | 1 | 53 | |
| GSE47630 | ZNF436 | 80818 | 8 | 3 | 29 | |
| GSE54993 | ZNF436 | 80818 | 2 | 1 | 67 | |
| GSE54994 | ZNF436 | 80818 | 11 | 4 | 38 | |
| GSE60625 | ZNF436 | 80818 | 0 | 0 | 11 | |
| GSE74703 | ZNF436 | 80818 | 1 | 4 | 31 | |
| GSE74704 | ZNF436 | 80818 | 0 | 0 | 20 | |
| TCGA | ZNF436 | 80818 | 9 | 23 | 64 |
Total number of gains: 38; Total number of losses: 51; Total Number of normals: 399.
Somatic mutations of ZNF436:
Generating mutation plots.
Highly correlated genes for ZNF436:
Showing top 20/1124 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF436 | PLA2G12A | 0.823979 | 4 | 0 | 4 |
| ZNF436 | BACE2 | 0.811009 | 3 | 0 | 3 |
| ZNF436 | WDR77 | 0.806073 | 3 | 0 | 3 |
| ZNF436 | FAM149B1 | 0.803315 | 4 | 0 | 4 |
| ZNF436 | RBM20 | 0.783523 | 4 | 0 | 4 |
| ZNF436 | OSBPL8 | 0.775274 | 4 | 0 | 4 |
| ZNF436 | PFDN5 | 0.770279 | 3 | 0 | 3 |
| ZNF436 | ZCCHC8 | 0.769 | 3 | 0 | 3 |
| ZNF436 | ZNF70 | 0.768858 | 3 | 0 | 3 |
| ZNF436 | CNOT10 | 0.768248 | 3 | 0 | 3 |
| ZNF436 | NDUFA2 | 0.765744 | 3 | 0 | 3 |
| ZNF436 | FPGT | 0.759348 | 3 | 0 | 3 |
| ZNF436 | GLUD1 | 0.757964 | 3 | 0 | 3 |
| ZNF436 | PRR15L | 0.756153 | 3 | 0 | 3 |
| ZNF436 | RRAGC | 0.755675 | 3 | 0 | 3 |
| ZNF436 | BCAR3 | 0.754482 | 3 | 0 | 3 |
| ZNF436 | APPL1 | 0.749541 | 5 | 0 | 5 |
| ZNF436 | PUS7L | 0.748837 | 3 | 0 | 3 |
| ZNF436 | EIF2B1 | 0.748432 | 3 | 0 | 3 |
| ZNF436 | NDUFS3 | 0.745407 | 3 | 0 | 3 |
For details and further investigation, click here
