| Full name: pellino E3 ubiquitin protein ligase family member 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q22.3 | ||
| Entrez ID: 57161 | HGNC ID: HGNC:8828 | Ensembl Gene: ENSG00000139946 | OMIM ID: 614798 |
| Drug and gene relationship at DGIdb | |||
Expression of PELI2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PELI2 | 57161 | 219132_at | 0.2161 | 0.8331 | |
| GSE20347 | PELI2 | 57161 | 219132_at | 0.8175 | 0.0139 | |
| GSE23400 | PELI2 | 57161 | 219132_at | 0.2093 | 0.0185 | |
| GSE26886 | PELI2 | 57161 | 219132_at | 1.4753 | 0.0035 | |
| GSE29001 | PELI2 | 57161 | 219132_at | 0.1119 | 0.7919 | |
| GSE38129 | PELI2 | 57161 | 219132_at | 0.3678 | 0.2288 | |
| GSE45670 | PELI2 | 57161 | 219132_at | -0.9659 | 0.0265 | |
| GSE53622 | PELI2 | 57161 | 19175 | 0.0986 | 0.5022 | |
| GSE53624 | PELI2 | 57161 | 19175 | 0.0888 | 0.5415 | |
| GSE63941 | PELI2 | 57161 | 219132_at | -0.7299 | 0.6600 | |
| GSE77861 | PELI2 | 57161 | 219132_at | 0.6905 | 0.0367 | |
| GSE97050 | PELI2 | 57161 | A_23_P65532 | -0.2227 | 0.5669 | |
| SRP007169 | PELI2 | 57161 | RNAseq | 3.6558 | 0.0000 | |
| SRP064894 | PELI2 | 57161 | RNAseq | 0.0430 | 0.8905 | |
| SRP133303 | PELI2 | 57161 | RNAseq | 0.3235 | 0.1811 | |
| SRP159526 | PELI2 | 57161 | RNAseq | 1.1012 | 0.0015 | |
| SRP193095 | PELI2 | 57161 | RNAseq | 0.0127 | 0.9716 | |
| SRP219564 | PELI2 | 57161 | RNAseq | 0.5454 | 0.1984 | |
| TCGA | PELI2 | 57161 | RNAseq | -0.5353 | 0.0022 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by PELI2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PELI2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PELI2 | 57161 | 8 | 3 | 19 | |
| GSE20123 | PELI2 | 57161 | 8 | 3 | 19 | |
| GSE43470 | PELI2 | 57161 | 9 | 1 | 33 | |
| GSE46452 | PELI2 | 57161 | 16 | 3 | 40 | |
| GSE47630 | PELI2 | 57161 | 11 | 10 | 19 | |
| GSE54993 | PELI2 | 57161 | 3 | 8 | 59 | |
| GSE54994 | PELI2 | 57161 | 19 | 4 | 30 | |
| GSE60625 | PELI2 | 57161 | 0 | 2 | 9 | |
| GSE74703 | PELI2 | 57161 | 8 | 1 | 27 | |
| GSE74704 | PELI2 | 57161 | 3 | 2 | 15 | |
| TCGA | PELI2 | 57161 | 32 | 14 | 50 |
Total number of gains: 117; Total number of losses: 51; Total Number of normals: 320.
Somatic mutations of PELI2:
Generating mutation plots.
Highly correlated genes for PELI2:
Showing top 20/813 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PELI2 | ZSCAN21 | 0.798683 | 4 | 0 | 4 |
| PELI2 | KDM4A | 0.769912 | 3 | 0 | 3 |
| PELI2 | PTPN14 | 0.7681 | 3 | 0 | 3 |
| PELI2 | ZNF691 | 0.76523 | 4 | 0 | 4 |
| PELI2 | TRIO | 0.757077 | 3 | 0 | 3 |
| PELI2 | ZCCHC7 | 0.755553 | 3 | 0 | 3 |
| PELI2 | ZNF7 | 0.752603 | 3 | 0 | 3 |
| PELI2 | LAMTOR4 | 0.744376 | 3 | 0 | 3 |
| PELI2 | MICU1 | 0.742207 | 3 | 0 | 3 |
| PELI2 | CHIC1 | 0.738565 | 3 | 0 | 3 |
| PELI2 | SLC37A3 | 0.737002 | 3 | 0 | 3 |
| PELI2 | ZNF251 | 0.735363 | 3 | 0 | 3 |
| PELI2 | DTNBP1 | 0.735322 | 3 | 0 | 3 |
| PELI2 | LNP1 | 0.732693 | 3 | 0 | 3 |
| PELI2 | STX2 | 0.730114 | 3 | 0 | 3 |
| PELI2 | SLC25A32 | 0.727994 | 3 | 0 | 3 |
| PELI2 | UPF1 | 0.72755 | 3 | 0 | 3 |
| PELI2 | ZNF850 | 0.723359 | 3 | 0 | 3 |
| PELI2 | NSMCE2 | 0.721962 | 3 | 0 | 3 |
| PELI2 | ZNF827 | 0.721321 | 3 | 0 | 3 |
For details and further investigation, click here
