PPP1R35

 

Full name: protein phosphatase 1 regulatory subunit 35 Alias Symbol: MGC22793
Type: protein-coding gene Cytoband: 7q22.1
Entrez ID: 221908 HGNC ID: HGNC:28320 Ensembl Gene: ENSG00000160813 OMIM ID: 
Screen Evidence:

 

Expression of PPP1R35:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PPP1R35 221908 226434_at 0.6832 0.1134
GSE26886 PPP1R35 221908 226434_at 1.8172 0.0000
GSE45670 PPP1R35 221908 226434_at 0.2738 0.1153
GSE53622 PPP1R35 221908 30384 0.4682 0.0000
GSE53624 PPP1R35 221908 30384 0.4576 0.0000
GSE63941 PPP1R35 221908 226434_at 1.6425 0.0017
GSE77861 PPP1R35 221908 226434_at 0.6060 0.0064
GSE97050 PPP1R35 221908 A_23_P82299 0.3083 0.2152
SRP007169 PPP1R35 221908 RNAseq -0.0586 0.8813
SRP008496 PPP1R35 221908 RNAseq 0.4570 0.2503
SRP064894 PPP1R35 221908 RNAseq 0.7344 0.0141
SRP133303 PPP1R35 221908 RNAseq 0.2261 0.2279
SRP159526 PPP1R35 221908 RNAseq 0.2131 0.2512
SRP193095 PPP1R35 221908 RNAseq 0.6369 0.0000
SRP219564 PPP1R35 221908 RNAseq 0.7351 0.0494

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by PPP1R35 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of PPP1R35:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PPP1R35 221908 13 0 17
GSE20123 PPP1R35 221908 13 0 17
GSE43470 PPP1R35 221908 7 2 34
GSE46452 PPP1R35 221908 11 1 47
GSE47630 PPP1R35 221908 7 3 30
GSE54993 PPP1R35 221908 1 9 60
GSE54994 PPP1R35 221908 16 3 34
GSE60625 PPP1R35 221908 0 0 11
GSE74703 PPP1R35 221908 7 1 28
GSE74704 PPP1R35 221908 9 0 11
TCGA PPP1R35 221908 52 6 38

Total number of gains: 136; Total number of losses: 25; Total Number of normals: 327.  

 

Somatic mutations of PPP1R35:

 

Generating mutation plots.

 

Highly correlated genes for PPP1R35:

 

Showing top 20/1574 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PPP1R35NENF0.876109303
PPP1R35SEL1L30.853472303
PPP1R35CHST150.841565303
PPP1R35SAFB20.84095303
PPP1R35GNB50.831625303
PPP1R35WDR810.819335303
PPP1R35NOL90.812082404
PPP1R35GALNT60.805137303
PPP1R35IFNGR10.801075303
PPP1R35FEZ10.795828303
PPP1R35INTS30.788416303
PPP1R35FTO0.788314303
PPP1R35NGRN0.787392303
PPP1R35ZNF3190.783951303
PPP1R35POP70.783572808
PPP1R35NAP1L10.783397303
PPP1R35MCM70.776133707
PPP1R35DGKD0.775401303
PPP1R35IFITM10.774283303
PPP1R35DDX100.767185404

For details and further investigation, click here