| Full name: phosphoribosyl pyrophosphate synthetase associated protein 2 | Alias Symbol: PAP41 | ||
| Type: protein-coding gene | Cytoband: 17p11.2 | ||
| Entrez ID: 5636 | HGNC ID: HGNC:9467 | Ensembl Gene: ENSG00000141127 | OMIM ID: 603762 |
| Drug and gene relationship at DGIdb | |||
Expression of PRPSAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRPSAP2 | 5636 | 203537_at | 0.2040 | 0.5512 | |
| GSE20347 | PRPSAP2 | 5636 | 203537_at | 0.5347 | 0.0140 | |
| GSE23400 | PRPSAP2 | 5636 | 203537_at | 0.4204 | 0.0000 | |
| GSE26886 | PRPSAP2 | 5636 | 203537_at | 0.4858 | 0.0430 | |
| GSE29001 | PRPSAP2 | 5636 | 203537_at | 0.4380 | 0.0823 | |
| GSE38129 | PRPSAP2 | 5636 | 203537_at | 0.7329 | 0.0000 | |
| GSE45670 | PRPSAP2 | 5636 | 203537_at | 0.4544 | 0.0124 | |
| GSE53622 | PRPSAP2 | 5636 | 80826 | 0.1576 | 0.0069 | |
| GSE53624 | PRPSAP2 | 5636 | 80826 | 0.0019 | 0.9768 | |
| GSE63941 | PRPSAP2 | 5636 | 203537_at | 1.1047 | 0.0292 | |
| GSE77861 | PRPSAP2 | 5636 | 203537_at | 0.6805 | 0.0232 | |
| GSE97050 | PRPSAP2 | 5636 | A_23_P49646 | 0.3154 | 0.1886 | |
| SRP007169 | PRPSAP2 | 5636 | RNAseq | 0.3619 | 0.4425 | |
| SRP008496 | PRPSAP2 | 5636 | RNAseq | 0.4298 | 0.1184 | |
| SRP064894 | PRPSAP2 | 5636 | RNAseq | 0.5115 | 0.0109 | |
| SRP133303 | PRPSAP2 | 5636 | RNAseq | 0.3400 | 0.0554 | |
| SRP159526 | PRPSAP2 | 5636 | RNAseq | 0.9323 | 0.0000 | |
| SRP193095 | PRPSAP2 | 5636 | RNAseq | 0.2580 | 0.0613 | |
| SRP219564 | PRPSAP2 | 5636 | RNAseq | 0.3785 | 0.2444 | |
| TCGA | PRPSAP2 | 5636 | RNAseq | 0.2040 | 0.0007 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PRPSAP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRPSAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRPSAP2 | 5636 | 4 | 3 | 23 | |
| GSE20123 | PRPSAP2 | 5636 | 4 | 4 | 22 | |
| GSE43470 | PRPSAP2 | 5636 | 1 | 5 | 37 | |
| GSE46452 | PRPSAP2 | 5636 | 34 | 1 | 24 | |
| GSE47630 | PRPSAP2 | 5636 | 7 | 1 | 32 | |
| GSE54993 | PRPSAP2 | 5636 | 3 | 3 | 64 | |
| GSE54994 | PRPSAP2 | 5636 | 6 | 6 | 41 | |
| GSE60625 | PRPSAP2 | 5636 | 4 | 0 | 7 | |
| GSE74703 | PRPSAP2 | 5636 | 1 | 2 | 33 | |
| GSE74704 | PRPSAP2 | 5636 | 3 | 1 | 16 | |
| TCGA | PRPSAP2 | 5636 | 19 | 24 | 53 |
Total number of gains: 86; Total number of losses: 50; Total Number of normals: 352.
Somatic mutations of PRPSAP2:
Generating mutation plots.
Highly correlated genes for PRPSAP2:
Showing top 20/1132 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRPSAP2 | TTC39C | 0.770875 | 3 | 0 | 3 |
| PRPSAP2 | NOL9 | 0.759801 | 3 | 0 | 3 |
| PRPSAP2 | PLD3 | 0.73656 | 3 | 0 | 3 |
| PRPSAP2 | KLF13 | 0.730997 | 4 | 0 | 3 |
| PRPSAP2 | FREM2 | 0.726196 | 3 | 0 | 3 |
| PRPSAP2 | PIEZO1 | 0.725495 | 3 | 0 | 3 |
| PRPSAP2 | NTPCR | 0.717242 | 4 | 0 | 4 |
| PRPSAP2 | HAS3 | 0.716669 | 4 | 0 | 4 |
| PRPSAP2 | BABAM1 | 0.714769 | 3 | 0 | 3 |
| PRPSAP2 | TXNRD1 | 0.709598 | 9 | 0 | 9 |
| PRPSAP2 | CD86 | 0.708092 | 3 | 0 | 3 |
| PRPSAP2 | GABRR1 | 0.704297 | 3 | 0 | 3 |
| PRPSAP2 | IWS1 | 0.698168 | 5 | 0 | 4 |
| PRPSAP2 | CEP290 | 0.694574 | 4 | 0 | 3 |
| PRPSAP2 | LRP12 | 0.684644 | 8 | 0 | 8 |
| PRPSAP2 | KDM1B | 0.683029 | 4 | 0 | 4 |
| PRPSAP2 | TRIO | 0.681344 | 4 | 0 | 4 |
| PRPSAP2 | ZNF567 | 0.677312 | 3 | 0 | 3 |
| PRPSAP2 | ZBED1 | 0.676594 | 3 | 0 | 3 |
| PRPSAP2 | DHRS13 | 0.674482 | 5 | 0 | 5 |
For details and further investigation, click here
