| Full name: BCL2 associated athanogene 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p12.1 | ||
| Entrez ID: 9532 | HGNC ID: HGNC:938 | Ensembl Gene: ENSG00000112208 | OMIM ID: 603882 |
| Drug and gene relationship at DGIdb | |||
Expression of BAG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BAG2 | 9532 | 209406_at | -0.6211 | 0.6441 | |
| GSE20347 | BAG2 | 9532 | 209406_at | 1.3330 | 0.0099 | |
| GSE23400 | BAG2 | 9532 | 209406_at | 0.4175 | 0.0597 | |
| GSE26886 | BAG2 | 9532 | 230750_at | 0.2741 | 0.0815 | |
| GSE29001 | BAG2 | 9532 | 209406_at | 0.7105 | 0.0274 | |
| GSE38129 | BAG2 | 9532 | 209406_at | 0.6759 | 0.2128 | |
| GSE45670 | BAG2 | 9532 | 209406_at | -0.8517 | 0.1841 | |
| GSE53622 | BAG2 | 9532 | 108812 | -0.0351 | 0.8639 | |
| GSE53624 | BAG2 | 9532 | 108812 | 0.7604 | 0.0000 | |
| GSE63941 | BAG2 | 9532 | 209406_at | -1.8521 | 0.2198 | |
| GSE77861 | BAG2 | 9532 | 209406_at | 1.3285 | 0.0619 | |
| GSE97050 | BAG2 | 9532 | A_23_P356554 | -0.7751 | 0.1194 | |
| SRP007169 | BAG2 | 9532 | RNAseq | 4.7043 | 0.0000 | |
| SRP008496 | BAG2 | 9532 | RNAseq | 4.8891 | 0.0000 | |
| SRP064894 | BAG2 | 9532 | RNAseq | 0.0618 | 0.8032 | |
| SRP133303 | BAG2 | 9532 | RNAseq | 0.2672 | 0.4798 | |
| SRP159526 | BAG2 | 9532 | RNAseq | 0.5330 | 0.3483 | |
| SRP193095 | BAG2 | 9532 | RNAseq | 1.8116 | 0.0000 | |
| SRP219564 | BAG2 | 9532 | RNAseq | -0.5582 | 0.5118 | |
| TCGA | BAG2 | 9532 | RNAseq | -0.0652 | 0.6277 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by BAG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BAG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BAG2 | 9532 | 7 | 2 | 21 | |
| GSE20123 | BAG2 | 9532 | 7 | 2 | 21 | |
| GSE43470 | BAG2 | 9532 | 4 | 0 | 39 | |
| GSE46452 | BAG2 | 9532 | 2 | 10 | 47 | |
| GSE47630 | BAG2 | 9532 | 7 | 5 | 28 | |
| GSE54993 | BAG2 | 9532 | 3 | 2 | 65 | |
| GSE54994 | BAG2 | 9532 | 9 | 4 | 40 | |
| GSE60625 | BAG2 | 9532 | 0 | 1 | 10 | |
| GSE74703 | BAG2 | 9532 | 4 | 0 | 32 | |
| GSE74704 | BAG2 | 9532 | 3 | 1 | 16 | |
| TCGA | BAG2 | 9532 | 22 | 10 | 64 |
Total number of gains: 68; Total number of losses: 37; Total Number of normals: 383.
Somatic mutations of BAG2:
Generating mutation plots.
Highly correlated genes for BAG2:
Showing top 20/954 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BAG2 | SMAD5 | 0.778256 | 3 | 0 | 3 |
| BAG2 | JMY | 0.773543 | 3 | 0 | 3 |
| BAG2 | WDR35 | 0.759147 | 3 | 0 | 3 |
| BAG2 | ZNF25 | 0.752564 | 3 | 0 | 3 |
| BAG2 | ANO6 | 0.746767 | 7 | 0 | 7 |
| BAG2 | FUNDC2 | 0.738503 | 3 | 0 | 3 |
| BAG2 | PI16 | 0.737507 | 3 | 0 | 3 |
| BAG2 | DOCK11 | 0.7334 | 5 | 0 | 5 |
| BAG2 | CXCL5 | 0.732509 | 3 | 0 | 3 |
| BAG2 | DUSP3 | 0.731291 | 4 | 0 | 4 |
| BAG2 | LAMA4 | 0.718845 | 10 | 0 | 10 |
| BAG2 | PLIN4 | 0.716957 | 4 | 0 | 4 |
| BAG2 | DNALI1 | 0.715506 | 5 | 0 | 5 |
| BAG2 | SACS | 0.715423 | 11 | 0 | 10 |
| BAG2 | CD99L2 | 0.713088 | 4 | 0 | 4 |
| BAG2 | ITGB1BP2 | 0.712707 | 3 | 0 | 3 |
| BAG2 | HNRNPUL2 | 0.712156 | 3 | 0 | 3 |
| BAG2 | DFFA | 0.709313 | 3 | 0 | 3 |
| BAG2 | COL28A1 | 0.705777 | 3 | 0 | 3 |
| BAG2 | ILK | 0.704947 | 6 | 0 | 5 |
For details and further investigation, click here
