| Full name: osteoclast associated Ig-like receptor | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 126014 | HGNC ID: HGNC:29960 | Ensembl Gene: ENSG00000170909 | OMIM ID: 606862 |
| Drug and gene relationship at DGIdb | |||
OSCAR involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04380 | Osteoclast differentiation |
Expression of OSCAR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSCAR | 126014 | 1554503_a_at | 0.2465 | 0.4975 | |
| GSE26886 | OSCAR | 126014 | 1554503_a_at | 0.2728 | 0.0614 | |
| GSE45670 | OSCAR | 126014 | 1554503_a_at | 0.2090 | 0.0472 | |
| GSE53622 | OSCAR | 126014 | 36216 | 0.3901 | 0.0000 | |
| GSE53624 | OSCAR | 126014 | 36216 | 0.1365 | 0.0049 | |
| GSE63941 | OSCAR | 126014 | 1554503_a_at | 0.0078 | 0.9639 | |
| GSE77861 | OSCAR | 126014 | 1554503_a_at | -0.0465 | 0.6145 | |
| GSE97050 | OSCAR | 126014 | A_33_P3387561 | 0.1059 | 0.6249 | |
| SRP064894 | OSCAR | 126014 | RNAseq | 1.6498 | 0.0000 | |
| SRP133303 | OSCAR | 126014 | RNAseq | 0.5873 | 0.0038 | |
| SRP159526 | OSCAR | 126014 | RNAseq | 0.2940 | 0.5146 | |
| SRP193095 | OSCAR | 126014 | RNAseq | 0.3621 | 0.0138 | |
| SRP219564 | OSCAR | 126014 | RNAseq | 1.0787 | 0.0412 | |
| TCGA | OSCAR | 126014 | RNAseq | 1.0244 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by OSCAR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OSCAR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSCAR | 126014 | 3 | 4 | 23 | |
| GSE20123 | OSCAR | 126014 | 3 | 3 | 24 | |
| GSE43470 | OSCAR | 126014 | 2 | 11 | 30 | |
| GSE46452 | OSCAR | 126014 | 45 | 1 | 13 | |
| GSE47630 | OSCAR | 126014 | 8 | 6 | 26 | |
| GSE54993 | OSCAR | 126014 | 17 | 4 | 49 | |
| GSE54994 | OSCAR | 126014 | 4 | 14 | 35 | |
| GSE60625 | OSCAR | 126014 | 9 | 0 | 2 | |
| GSE74703 | OSCAR | 126014 | 2 | 7 | 27 | |
| GSE74704 | OSCAR | 126014 | 3 | 1 | 16 | |
| TCGA | OSCAR | 126014 | 19 | 15 | 62 |
Total number of gains: 115; Total number of losses: 66; Total Number of normals: 307.
Somatic mutations of OSCAR:
Generating mutation plots.
Highly correlated genes for OSCAR:
Showing top 20/84 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSCAR | BBS12 | 0.738098 | 3 | 0 | 3 |
| OSCAR | HEYL | 0.736938 | 3 | 0 | 3 |
| OSCAR | HELB | 0.712434 | 3 | 0 | 3 |
| OSCAR | G3BP2 | 0.694162 | 3 | 0 | 3 |
| OSCAR | OR2T12 | 0.685529 | 3 | 0 | 3 |
| OSCAR | SEC16A | 0.685135 | 3 | 0 | 3 |
| OSCAR | LRRD1 | 0.682488 | 4 | 0 | 4 |
| OSCAR | ZNF23 | 0.678278 | 3 | 0 | 3 |
| OSCAR | SPIC | 0.677803 | 3 | 0 | 3 |
| OSCAR | ST3GAL6 | 0.67709 | 3 | 0 | 3 |
| OSCAR | IL18BP | 0.675993 | 3 | 0 | 3 |
| OSCAR | PFKFB2 | 0.670006 | 3 | 0 | 3 |
| OSCAR | FCER1G | 0.662062 | 4 | 0 | 3 |
| OSCAR | ZNF8 | 0.650259 | 3 | 0 | 3 |
| OSCAR | EIF2S1 | 0.648465 | 3 | 0 | 3 |
| OSCAR | SLC41A2 | 0.647837 | 4 | 0 | 3 |
| OSCAR | PSKH1 | 0.647627 | 3 | 0 | 3 |
| OSCAR | VAX2 | 0.642248 | 4 | 0 | 3 |
| OSCAR | SH3KBP1 | 0.640969 | 3 | 0 | 3 |
| OSCAR | CCNK | 0.640464 | 3 | 0 | 3 |
For details and further investigation, click here
