| Full name: SEC24 homolog D, COPII coat complex component | Alias Symbol: KIAA0755 | ||
| Type: protein-coding gene | Cytoband: 4q26 | ||
| Entrez ID: 9871 | HGNC ID: HGNC:10706 | Ensembl Gene: ENSG00000150961 | OMIM ID: 607186 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC24D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC24D | 9871 | 202375_at | 0.0443 | 0.9518 | |
| GSE20347 | SEC24D | 9871 | 202375_at | 0.2312 | 0.2626 | |
| GSE23400 | SEC24D | 9871 | 202375_at | 0.2989 | 0.0002 | |
| GSE26886 | SEC24D | 9871 | 202375_at | 0.8128 | 0.0381 | |
| GSE29001 | SEC24D | 9871 | 202375_at | -0.1396 | 0.7613 | |
| GSE38129 | SEC24D | 9871 | 202375_at | 0.2790 | 0.1345 | |
| GSE45670 | SEC24D | 9871 | 202375_at | 0.1159 | 0.6638 | |
| GSE53622 | SEC24D | 9871 | 76979 | 0.6207 | 0.0000 | |
| GSE53624 | SEC24D | 9871 | 45374 | 0.3638 | 0.0035 | |
| GSE63941 | SEC24D | 9871 | 202375_at | -3.0302 | 0.0015 | |
| GSE77861 | SEC24D | 9871 | 202375_at | 0.2259 | 0.3265 | |
| GSE97050 | SEC24D | 9871 | A_23_P159382 | 0.5252 | 0.1403 | |
| SRP007169 | SEC24D | 9871 | RNAseq | 1.8179 | 0.0000 | |
| SRP008496 | SEC24D | 9871 | RNAseq | 2.0347 | 0.0000 | |
| SRP064894 | SEC24D | 9871 | RNAseq | 0.7353 | 0.0159 | |
| SRP133303 | SEC24D | 9871 | RNAseq | 1.0582 | 0.0000 | |
| SRP159526 | SEC24D | 9871 | RNAseq | 0.4422 | 0.0248 | |
| SRP193095 | SEC24D | 9871 | RNAseq | 0.0373 | 0.8881 | |
| SRP219564 | SEC24D | 9871 | RNAseq | 0.8058 | 0.1204 | |
| TCGA | SEC24D | 9871 | RNAseq | -0.1575 | 0.0071 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by SEC24D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC24D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC24D | 9871 | 0 | 13 | 17 | |
| GSE20123 | SEC24D | 9871 | 1 | 13 | 16 | |
| GSE43470 | SEC24D | 9871 | 0 | 13 | 30 | |
| GSE46452 | SEC24D | 9871 | 1 | 36 | 22 | |
| GSE47630 | SEC24D | 9871 | 0 | 22 | 18 | |
| GSE54993 | SEC24D | 9871 | 9 | 0 | 61 | |
| GSE54994 | SEC24D | 9871 | 1 | 10 | 42 | |
| GSE60625 | SEC24D | 9871 | 0 | 1 | 10 | |
| GSE74703 | SEC24D | 9871 | 0 | 11 | 25 | |
| GSE74704 | SEC24D | 9871 | 0 | 7 | 13 | |
| TCGA | SEC24D | 9871 | 9 | 34 | 53 |
Total number of gains: 21; Total number of losses: 160; Total Number of normals: 307.
Somatic mutations of SEC24D:
Generating mutation plots.
Highly correlated genes for SEC24D:
Showing top 20/710 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC24D | MICAL1 | 0.787079 | 3 | 0 | 3 |
| SEC24D | NUB1 | 0.776592 | 3 | 0 | 3 |
| SEC24D | SMPD1 | 0.757753 | 3 | 0 | 3 |
| SEC24D | RAP1GDS1 | 0.726323 | 3 | 0 | 3 |
| SEC24D | CFHR3 | 0.723324 | 3 | 0 | 3 |
| SEC24D | PSMD8 | 0.723029 | 3 | 0 | 3 |
| SEC24D | USP38 | 0.714656 | 3 | 0 | 3 |
| SEC24D | CEP170 | 0.713633 | 3 | 0 | 3 |
| SEC24D | B3GALT2 | 0.713423 | 3 | 0 | 3 |
| SEC24D | TMEM263 | 0.713027 | 5 | 0 | 5 |
| SEC24D | NECAP2 | 0.709634 | 3 | 0 | 3 |
| SEC24D | OSTC | 0.707147 | 7 | 0 | 7 |
| SEC24D | HIBADH | 0.70543 | 3 | 0 | 3 |
| SEC24D | SSBP4 | 0.704778 | 3 | 0 | 3 |
| SEC24D | SETD7 | 0.704056 | 3 | 0 | 3 |
| SEC24D | SERPINB9 | 0.703671 | 4 | 0 | 4 |
| SEC24D | CERK | 0.701305 | 4 | 0 | 4 |
| SEC24D | GLIS3 | 0.701038 | 5 | 0 | 4 |
| SEC24D | ATG7 | 0.700584 | 3 | 0 | 3 |
| SEC24D | BBS12 | 0.696918 | 4 | 0 | 4 |
For details and further investigation, click here
