TRIM32

 

Full name: tripartite motif containing 32 Alias Symbol: HT2A|TATIP|BBS11
Type: protein-coding gene Cytoband: 9q33.1
Entrez ID: 22954 HGNC ID: HGNC:16380 Ensembl Gene: ENSG00000119401 OMIM ID: 602290
Drug and gene relationship at DGIdb

 

Expression of TRIM32:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRIM32 22954 203846_at -0.2252 0.4399
GSE20347 TRIM32 22954 203846_at 0.2124 0.4221
GSE23400 TRIM32 22954 203846_at 0.1033 0.0730
GSE26886 TRIM32 22954 203846_at 0.3501 0.0371
GSE29001 TRIM32 22954 203846_at 0.3546 0.0369
GSE38129 TRIM32 22954 203846_at 0.1597 0.4010
GSE45670 TRIM32 22954 203846_at 0.1364 0.5679
GSE53622 TRIM32 22954 14671 0.1639 0.1214
GSE53624 TRIM32 22954 14671 0.5408 0.0002
GSE63941 TRIM32 22954 203846_at -0.2292 0.6099
GSE77861 TRIM32 22954 203846_at 0.1166 0.5962
GSE97050 TRIM32 22954 A_23_P112311 -0.1924 0.4922
SRP007169 TRIM32 22954 RNAseq 0.9820 0.0627
SRP008496 TRIM32 22954 RNAseq 1.3783 0.0000
SRP064894 TRIM32 22954 RNAseq 0.7712 0.0000
SRP133303 TRIM32 22954 RNAseq 0.2668 0.1896
SRP159526 TRIM32 22954 RNAseq 0.1802 0.5753
SRP193095 TRIM32 22954 RNAseq 0.4008 0.0001
SRP219564 TRIM32 22954 RNAseq 0.3317 0.3263
TCGA TRIM32 22954 RNAseq 0.0389 0.5975

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by TRIM32 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TRIM32:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRIM32 22954 4 10 16
GSE20123 TRIM32 22954 4 10 16
GSE43470 TRIM32 22954 4 3 36
GSE46452 TRIM32 22954 6 13 40
GSE47630 TRIM32 22954 3 16 21
GSE54993 TRIM32 22954 3 3 64
GSE54994 TRIM32 22954 9 11 33
GSE60625 TRIM32 22954 0 0 11
GSE74703 TRIM32 22954 4 3 29
GSE74704 TRIM32 22954 2 7 11
TCGA TRIM32 22954 26 24 46

Total number of gains: 65; Total number of losses: 100; Total Number of normals: 323.  


 

Somatic mutations of TRIM32:

 

Generating mutation plots.

 

Highly correlated genes for TRIM32:

 

Showing top 20/434 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRIM32TMEM2180.763949303
TRIM32XRCC60.723984303
TRIM32CPE0.722132303
TRIM32MRPL420.714911303
TRIM32PET1170.712695303
TRIM32TRPC10.71018303
TRIM32RASSF30.692132303
TRIM32ERLEC10.691478303
TRIM32ERVW-10.690894303
TRIM32THUMPD10.690048404
TRIM32TTC370.689714303
TRIM32PPP1CC0.687014303
TRIM32CEP440.686576303
TRIM32SRRT0.68624303
TRIM32SNX70.685363303
TRIM32KTI120.682206303
TRIM32LGALS80.680695303
TRIM32IGSF60.67636303
TRIM32C17orf750.676139403
TRIM32TLR10.674815404

For details and further investigation, click here