| Full name: bromodomain testis associated | Alias Symbol: BRD6|CT9 | ||
| Type: protein-coding gene | Cytoband: 1p22.1 | ||
| Entrez ID: 676 | HGNC ID: HGNC:1105 | Ensembl Gene: ENSG00000137948 | OMIM ID: 602144 |
| Drug and gene relationship at DGIdb | |||
Expression of BRDT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BRDT | 676 | 206787_at | 0.7929 | 0.4492 | |
| GSE20347 | BRDT | 676 | 206787_at | 0.1201 | 0.3083 | |
| GSE23400 | BRDT | 676 | 206787_at | -0.0126 | 0.7267 | |
| GSE26886 | BRDT | 676 | 206787_at | 0.0513 | 0.6897 | |
| GSE29001 | BRDT | 676 | 206787_at | 0.0721 | 0.4807 | |
| GSE38129 | BRDT | 676 | 206787_at | 0.0810 | 0.3361 | |
| GSE45670 | BRDT | 676 | 206787_at | 0.1660 | 0.3653 | |
| GSE53622 | BRDT | 676 | 67160 | 1.0017 | 0.0253 | |
| GSE53624 | BRDT | 676 | 67160 | 1.7436 | 0.0000 | |
| GSE63941 | BRDT | 676 | 206787_at | 0.7934 | 0.5856 | |
| GSE77861 | BRDT | 676 | 206787_at | 0.1692 | 0.6065 | |
| GSE97050 | BRDT | 676 | A_23_P136589 | 0.3559 | 0.2714 | |
| TCGA | BRDT | 676 | RNAseq | 3.4042 | 0.0249 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by BRDT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BRDT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BRDT | 676 | 0 | 8 | 22 | |
| GSE20123 | BRDT | 676 | 0 | 8 | 22 | |
| GSE43470 | BRDT | 676 | 2 | 5 | 36 | |
| GSE46452 | BRDT | 676 | 1 | 1 | 57 | |
| GSE47630 | BRDT | 676 | 8 | 5 | 27 | |
| GSE54993 | BRDT | 676 | 0 | 1 | 69 | |
| GSE54994 | BRDT | 676 | 6 | 3 | 44 | |
| GSE60625 | BRDT | 676 | 0 | 0 | 11 | |
| GSE74703 | BRDT | 676 | 1 | 4 | 31 | |
| GSE74704 | BRDT | 676 | 0 | 5 | 15 | |
| TCGA | BRDT | 676 | 6 | 24 | 66 |
Total number of gains: 24; Total number of losses: 64; Total Number of normals: 400.
Somatic mutations of BRDT:
Generating mutation plots.
Highly correlated genes for BRDT:
Showing top 20/163 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BRDT | AP3M2 | 0.766105 | 3 | 0 | 3 |
| BRDT | PXMP2 | 0.742812 | 3 | 0 | 3 |
| BRDT | NAIF1 | 0.713368 | 3 | 0 | 3 |
| BRDT | ZKSCAN5 | 0.712564 | 3 | 0 | 3 |
| BRDT | SLC7A6 | 0.711982 | 3 | 0 | 3 |
| BRDT | NOL9 | 0.710345 | 3 | 0 | 3 |
| BRDT | PCDH19 | 0.710268 | 3 | 0 | 3 |
| BRDT | FAM86C1 | 0.708885 | 3 | 0 | 3 |
| BRDT | NARF | 0.69597 | 3 | 0 | 3 |
| BRDT | MRPS23 | 0.688034 | 3 | 0 | 3 |
| BRDT | ANAPC11 | 0.682648 | 4 | 0 | 4 |
| BRDT | POU5F1B | 0.681824 | 3 | 0 | 3 |
| BRDT | CLEC2L | 0.680461 | 3 | 0 | 3 |
| BRDT | SLC7A6OS | 0.678802 | 3 | 0 | 3 |
| BRDT | POP7 | 0.674943 | 3 | 0 | 3 |
| BRDT | GNB1 | 0.674654 | 3 | 0 | 3 |
| BRDT | ASPRV1 | 0.672285 | 3 | 0 | 3 |
| BRDT | CCNF | 0.672039 | 3 | 0 | 3 |
| BRDT | FANCB | 0.670805 | 3 | 0 | 3 |
| BRDT | SEC61A2 | 0.670619 | 4 | 0 | 4 |
For details and further investigation, click here
