| Full name: family with sequence similarity 86 member C1 | Alias Symbol: FLJ10661|FLJ27199 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 55199 | HGNC ID: HGNC:25561 | Ensembl Gene: ENSG00000158483 | OMIM ID: 616124 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM86C1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM86C1 | 55199 | 220353_at | 0.9970 | 0.0487 | |
| GSE20347 | FAM86C1 | 55199 | 220353_at | 0.4757 | 0.0087 | |
| GSE23400 | FAM86C1 | 55199 | 220353_at | 0.1475 | 0.0018 | |
| GSE26886 | FAM86C1 | 55199 | 220353_at | 0.4772 | 0.0003 | |
| GSE29001 | FAM86C1 | 55199 | 220353_at | 0.1263 | 0.3126 | |
| GSE38129 | FAM86C1 | 55199 | 220353_at | 0.4434 | 0.0012 | |
| GSE45670 | FAM86C1 | 55199 | 220353_at | 0.4747 | 0.0002 | |
| GSE63941 | FAM86C1 | 55199 | 220353_at | 1.3502 | 0.0039 | |
| GSE77861 | FAM86C1 | 55199 | 220353_at | 0.1806 | 0.3330 | |
| GSE97050 | FAM86C1 | A_21_P0011081 | 0.3897 | 0.2976 | ||
| SRP007169 | FAM86C1 | 55199 | RNAseq | -0.6103 | 0.1704 | |
| SRP008496 | FAM86C1 | 55199 | RNAseq | 0.0724 | 0.8730 | |
| SRP064894 | FAM86C1 | 55199 | RNAseq | 0.4798 | 0.0645 | |
| SRP133303 | FAM86C1 | 55199 | RNAseq | 2.3108 | 0.0000 | |
| SRP159526 | FAM86C1 | 55199 | RNAseq | 0.8461 | 0.2014 | |
| SRP193095 | FAM86C1 | 55199 | RNAseq | 0.6442 | 0.0108 | |
| SRP219564 | FAM86C1 | 55199 | RNAseq | 1.4841 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Copy number change of FAM86C1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM86C1 | 55199 | 11 | 6 | 13 | |
| GSE20123 | FAM86C1 | 55199 | 11 | 6 | 13 | |
| GSE43470 | FAM86C1 | 55199 | 7 | 4 | 32 | |
| GSE46452 | FAM86C1 | 55199 | 13 | 16 | 30 | |
| GSE47630 | FAM86C1 | 55199 | 11 | 9 | 20 | |
| GSE54993 | FAM86C1 | 55199 | 7 | 4 | 59 | |
| GSE54994 | FAM86C1 | 55199 | 14 | 11 | 28 | |
| GSE60625 | FAM86C1 | 55199 | 0 | 7 | 4 | |
| GSE74703 | FAM86C1 | 55199 | 6 | 3 | 27 | |
| GSE74704 | FAM86C1 | 55199 | 7 | 4 | 9 | |
| TCGA | FAM86C1 | 55199 | 38 | 19 | 39 |
Total number of gains: 125; Total number of losses: 89; Total Number of normals: 274.
Somatic mutations of FAM86C1:
Generating mutation plots.
Highly correlated genes for FAM86C1:
Showing top 20/1218 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM86C1 | ALG1 | 0.799094 | 3 | 0 | 3 |
| FAM86C1 | FAR2 | 0.795285 | 3 | 0 | 3 |
| FAM86C1 | PSPC1 | 0.792121 | 3 | 0 | 3 |
| FAM86C1 | IFFO2 | 0.780537 | 3 | 0 | 3 |
| FAM86C1 | SENP2 | 0.777533 | 3 | 0 | 3 |
| FAM86C1 | PDCD2L | 0.772723 | 3 | 0 | 3 |
| FAM86C1 | NOSIP | 0.769908 | 3 | 0 | 3 |
| FAM86C1 | TRIM59 | 0.768946 | 3 | 0 | 3 |
| FAM86C1 | SIX4 | 0.760846 | 4 | 0 | 4 |
| FAM86C1 | MZT1 | 0.757185 | 3 | 0 | 3 |
| FAM86C1 | LYAR | 0.757056 | 3 | 0 | 3 |
| FAM86C1 | GEN1 | 0.756726 | 3 | 0 | 3 |
| FAM86C1 | PLEKHH1 | 0.754141 | 3 | 0 | 3 |
| FAM86C1 | STX16 | 0.750841 | 3 | 0 | 3 |
| FAM86C1 | DNAJC19 | 0.749776 | 3 | 0 | 3 |
| FAM86C1 | ANLN | 0.749272 | 3 | 0 | 3 |
| FAM86C1 | R3HDM2 | 0.749091 | 3 | 0 | 3 |
| FAM86C1 | ACBD6 | 0.747038 | 3 | 0 | 3 |
| FAM86C1 | SDR39U1 | 0.745754 | 3 | 0 | 3 |
| FAM86C1 | KIAA1324L | 0.745328 | 4 | 0 | 4 |
For details and further investigation, click here
