| Full name: aspartic peptidase retroviral like 1 | Alias Symbol: Taps|SASPase|FLJ25084 | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 151516 | HGNC ID: HGNC:26321 | Ensembl Gene: ENSG00000244617 | OMIM ID: 611765 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ASPRV1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASPRV1 | 151516 | 235514_at | 0.3881 | 0.3321 | |
| GSE26886 | ASPRV1 | 151516 | 235514_at | 0.5026 | 0.2933 | |
| GSE45670 | ASPRV1 | 151516 | 235514_at | 1.1125 | 0.0342 | |
| GSE53622 | ASPRV1 | 151516 | 89884 | 1.5557 | 0.0000 | |
| GSE53624 | ASPRV1 | 151516 | 89884 | 1.5692 | 0.0000 | |
| GSE63941 | ASPRV1 | 151516 | 235514_at | -0.1888 | 0.3880 | |
| GSE77861 | ASPRV1 | 151516 | 235514_at | 0.3794 | 0.3913 | |
| GSE97050 | ASPRV1 | 151516 | A_23_P417383 | 1.1192 | 0.2522 | |
| SRP007169 | ASPRV1 | 151516 | RNAseq | 2.8839 | 0.0017 | |
| SRP064894 | ASPRV1 | 151516 | RNAseq | 1.5268 | 0.0005 | |
| SRP133303 | ASPRV1 | 151516 | RNAseq | 1.1802 | 0.0274 | |
| SRP159526 | ASPRV1 | 151516 | RNAseq | 2.2966 | 0.0171 | |
| SRP193095 | ASPRV1 | 151516 | RNAseq | 1.2435 | 0.0002 | |
| TCGA | ASPRV1 | 151516 | RNAseq | -0.1518 | 0.5666 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by ASPRV1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASPRV1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASPRV1 | 151516 | 11 | 1 | 18 | |
| GSE20123 | ASPRV1 | 151516 | 11 | 1 | 18 | |
| GSE43470 | ASPRV1 | 151516 | 3 | 0 | 40 | |
| GSE46452 | ASPRV1 | 151516 | 2 | 3 | 54 | |
| GSE47630 | ASPRV1 | 151516 | 7 | 0 | 33 | |
| GSE54993 | ASPRV1 | 151516 | 0 | 6 | 64 | |
| GSE54994 | ASPRV1 | 151516 | 12 | 0 | 41 | |
| GSE60625 | ASPRV1 | 151516 | 0 | 3 | 8 | |
| GSE74703 | ASPRV1 | 151516 | 3 | 0 | 33 | |
| GSE74704 | ASPRV1 | 151516 | 9 | 1 | 10 | |
| TCGA | ASPRV1 | 151516 | 36 | 2 | 58 |
Total number of gains: 94; Total number of losses: 17; Total Number of normals: 377.
Somatic mutations of ASPRV1:
Generating mutation plots.
Highly correlated genes for ASPRV1:
Showing top 20/105 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASPRV1 | CDSN | 0.70408 | 6 | 0 | 6 |
| ASPRV1 | GDAP1 | 0.673432 | 4 | 0 | 4 |
| ASPRV1 | IL1F10 | 0.672723 | 3 | 0 | 3 |
| ASPRV1 | BRDT | 0.672285 | 3 | 0 | 3 |
| ASPRV1 | LOR | 0.660182 | 5 | 0 | 3 |
| ASPRV1 | DSC1 | 0.654003 | 7 | 0 | 7 |
| ASPRV1 | KLK14 | 0.650141 | 5 | 0 | 4 |
| ASPRV1 | RDH11 | 0.649197 | 3 | 0 | 3 |
| ASPRV1 | GLB1L | 0.640633 | 3 | 0 | 3 |
| ASPRV1 | RMI2 | 0.637474 | 4 | 0 | 3 |
| ASPRV1 | LCE2B | 0.629084 | 5 | 0 | 5 |
| ASPRV1 | DPP4 | 0.62643 | 5 | 0 | 3 |
| ASPRV1 | CTSA | 0.616611 | 5 | 0 | 3 |
| ASPRV1 | ZSWIM1 | 0.614723 | 5 | 0 | 5 |
| ASPRV1 | TUFM | 0.614316 | 4 | 0 | 3 |
| ASPRV1 | FAM192A | 0.606942 | 5 | 0 | 4 |
| ASPRV1 | SPRR2G | 0.605731 | 7 | 0 | 6 |
| ASPRV1 | NUP93 | 0.605584 | 4 | 0 | 3 |
| ASPRV1 | GRIN2D | 0.605392 | 5 | 0 | 4 |
| ASPRV1 | NFATC3 | 0.602039 | 4 | 0 | 3 |
For details and further investigation, click here
