Full name: cyclin F	Alias Symbol: FBX1|FBXO1
Type: protein-coding gene	Cytoband: 16p13.3
Entrez ID: 899	HGNC ID: HGNC:1591	Ensembl Gene: ENSG00000162063	OMIM ID: 600227
Drug and gene relationship at DGIdb
Screen Evidence: Knocking out of this gene by CRIPR/Cas9 screen found 5/325 cell lines had fitness change in Project Score. Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

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Expression of CCNF:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	CCNF	899	204826_at	0.8758	0.0378	Show
GSE20347	CCNF	899	204826_at	0.5828	0.0000	Show
GSE23400	CCNF	899	204826_at	0.6937	0.0000	Show
GSE26886	CCNF	899	204826_at	0.4008	0.0351	Show
GSE29001	CCNF	899	204826_at	0.8087	0.0016	Show
GSE38129	CCNF	899	204826_at	0.9461	0.0000	Show
GSE45670	CCNF	899	204826_at	0.9365	0.0000	Show
GSE53622	CCNF	899	57367	1.7226	0.0000	Show
GSE53624	CCNF	899	57367	1.6360	0.0000	Show
GSE63941	CCNF	899	204826_at	1.1534	0.0070	Show
GSE77861	CCNF	899	204826_at	0.1668	0.2616	Show
GSE97050	CCNF	899	A_24_P193592	1.0866	0.1985	Show
SRP007169	CCNF	899	RNAseq	1.6887	0.0004	Show
SRP008496	CCNF	899	RNAseq	1.0242	0.0037	Show
SRP064894	CCNF	899	RNAseq	1.2509	0.0000	Show
SRP133303	CCNF	899	RNAseq	1.4942	0.0000	Show
SRP159526	CCNF	899	RNAseq	1.3501	0.0001	Show
SRP193095	CCNF	899	RNAseq	1.0436	0.0000	Show
SRP219564	CCNF	899	RNAseq	0.9413	0.1035	Show
TCGA	CCNF	899	RNAseq	0.8268	0.0000	Show

Upregulated datasets: 9; Downregulated datasets: 0.  Download Data

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Survival by CCNF expression:

 

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Copy number change of CCNF:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	CCNF	899	5	5	20	Show
GSE20123	CCNF	899	5	4	21	Show
GSE43470	CCNF	899	4	7	32	Show
GSE46452	CCNF	899	38	1	20	Show
GSE47630	CCNF	899	13	6	21	Show
GSE54993	CCNF	899	3	5	62	Show
GSE54994	CCNF	899	5	9	39	Show
GSE60625	CCNF	899	4	0	7	Show
GSE74703	CCNF	899	4	5	27	Show
GSE74704	CCNF	899	3	2	15	Show
TCGA	CCNF	899	20	13	63	Show

Total number of gains: 104; Total number of losses: 57; Total Number of normals: 327.  Download Data

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Somatic mutations of CCNF:

 

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Highly correlated genes for CCNF:

 

Showing top 20/1887 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
CCNF	UCK2	0.805302	3	0	3
CCNF	DTL	0.798797	12	0	12
CCNF	STIL	0.796131	11	0	11
CCNF	MMS22L	0.796018	3	0	3
CCNF	UBE2C	0.792522	12	0	12
CCNF	TPX2	0.789845	12	0	12
CCNF	KIF2C	0.789639	12	0	11
CCNF	DKC1	0.788333	3	0	3
CCNF	RACGAP1	0.787525	9	0	8
CCNF	AURKA	0.786928	12	0	11
CCNF	GINS1	0.781953	12	0	12
CCNF	CCNA2	0.777587	11	0	10
CCNF	CEP55	0.774566	11	0	10
CCNF	CENPN	0.772695	11	0	10
CCNF	WDHD1	0.772626	11	0	11
CCNF	LRRC58	0.771368	3	0	3
CCNF	ESCO2	0.76905	7	0	7
CCNF	MYBL2	0.767665	12	0	12
CCNF	BIRC5	0.767517	13	0	12
CCNF	CENPW	0.767193	7	0	6

For details and further investigation, click here