| Full name: mitochondrial ribosomal protein S23 | Alias Symbol: MRP-S23|CGI-138|HSPC329 | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 51649 | HGNC ID: HGNC:14509 | Ensembl Gene: ENSG00000181610 | OMIM ID: 611985 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPS23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS23 | 51649 | 223156_at | 0.5630 | 0.1154 | |
| GSE26886 | MRPS23 | 51649 | 223156_at | 1.1236 | 0.0000 | |
| GSE45670 | MRPS23 | 51649 | 223156_at | 0.4552 | 0.0375 | |
| GSE53622 | MRPS23 | 51649 | 76488 | 0.7128 | 0.0000 | |
| GSE53624 | MRPS23 | 51649 | 76488 | 0.9389 | 0.0000 | |
| GSE63941 | MRPS23 | 51649 | 223156_at | 0.5988 | 0.0783 | |
| GSE77861 | MRPS23 | 51649 | 223156_at | 0.8025 | 0.0108 | |
| GSE97050 | MRPS23 | 51649 | A_23_P106998 | 0.3024 | 0.4516 | |
| SRP007169 | MRPS23 | 51649 | RNAseq | 0.7600 | 0.0485 | |
| SRP008496 | MRPS23 | 51649 | RNAseq | 0.8658 | 0.0002 | |
| SRP064894 | MRPS23 | 51649 | RNAseq | 0.5763 | 0.0046 | |
| SRP133303 | MRPS23 | 51649 | RNAseq | 0.7319 | 0.0000 | |
| SRP159526 | MRPS23 | 51649 | RNAseq | 0.5687 | 0.0324 | |
| SRP193095 | MRPS23 | 51649 | RNAseq | 0.2349 | 0.0017 | |
| SRP219564 | MRPS23 | 51649 | RNAseq | 0.6380 | 0.0535 | |
| TCGA | MRPS23 | 51649 | RNAseq | 0.0311 | 0.5717 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MRPS23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS23 | 51649 | 5 | 1 | 24 | |
| GSE20123 | MRPS23 | 51649 | 5 | 1 | 24 | |
| GSE43470 | MRPS23 | 51649 | 4 | 0 | 39 | |
| GSE46452 | MRPS23 | 51649 | 32 | 0 | 27 | |
| GSE47630 | MRPS23 | 51649 | 7 | 1 | 32 | |
| GSE54993 | MRPS23 | 51649 | 2 | 5 | 63 | |
| GSE54994 | MRPS23 | 51649 | 8 | 6 | 39 | |
| GSE60625 | MRPS23 | 51649 | 4 | 0 | 7 | |
| GSE74703 | MRPS23 | 51649 | 4 | 0 | 32 | |
| GSE74704 | MRPS23 | 51649 | 4 | 1 | 15 | |
| TCGA | MRPS23 | 51649 | 27 | 7 | 62 |
Total number of gains: 102; Total number of losses: 22; Total Number of normals: 364.
Somatic mutations of MRPS23:
Generating mutation plots.
Highly correlated genes for MRPS23:
Showing top 20/1914 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS23 | RPA3 | 0.759923 | 8 | 0 | 8 |
| MRPS23 | FHL3 | 0.758211 | 3 | 0 | 3 |
| MRPS23 | MFHAS1 | 0.74286 | 7 | 0 | 7 |
| MRPS23 | MMS22L | 0.741841 | 3 | 0 | 3 |
| MRPS23 | RUVBL1 | 0.735189 | 9 | 0 | 9 |
| MRPS23 | TACO1 | 0.729983 | 8 | 0 | 6 |
| MRPS23 | MRPL47 | 0.728884 | 8 | 0 | 8 |
| MRPS23 | NTMT1 | 0.728826 | 6 | 0 | 6 |
| MRPS23 | SNAP47 | 0.728028 | 3 | 0 | 3 |
| MRPS23 | TSN | 0.727501 | 6 | 0 | 6 |
| MRPS23 | MED30 | 0.727261 | 9 | 0 | 9 |
| MRPS23 | PRPS1 | 0.721734 | 8 | 0 | 8 |
| MRPS23 | NOL11 | 0.721225 | 9 | 0 | 9 |
| MRPS23 | EME1 | 0.720363 | 6 | 0 | 6 |
| MRPS23 | COL4A1 | 0.720029 | 6 | 0 | 6 |
| MRPS23 | SOAT1 | 0.719849 | 4 | 0 | 4 |
| MRPS23 | RNASEH1 | 0.719792 | 7 | 0 | 7 |
| MRPS23 | TRAM2 | 0.719511 | 7 | 0 | 6 |
| MRPS23 | ELAC2 | 0.719008 | 3 | 0 | 3 |
| MRPS23 | USP42 | 0.718777 | 5 | 0 | 5 |
For details and further investigation, click here
