| Full name: FA complementation group B | Alias Symbol: FAB|FLJ34064|FAAP95 | ||
| Type: protein-coding gene | Cytoband: Xp22.2 | ||
| Entrez ID: 2187 | HGNC ID: HGNC:3583 | Ensembl Gene: ENSG00000181544 | OMIM ID: 300515 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
FANCB involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03460 | Fanconi anemia pathway |
Expression of FANCB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FANCB | 2187 | 243597_at | 0.2003 | 0.6099 | |
| GSE26886 | FANCB | 2187 | 1553244_at | 0.0834 | 0.5815 | |
| GSE45670 | FANCB | 2187 | 1553244_at | 0.5770 | 0.0000 | |
| GSE53622 | FANCB | 2187 | 46995 | 1.4420 | 0.0000 | |
| GSE53624 | FANCB | 2187 | 46995 | 1.5606 | 0.0000 | |
| GSE63941 | FANCB | 2187 | 1557218_s_at | 0.9060 | 0.1184 | |
| GSE77861 | FANCB | 2187 | 1557218_s_at | 0.1590 | 0.0881 | |
| GSE97050 | FANCB | 2187 | A_23_P356021 | 0.7306 | 0.1675 | |
| SRP007169 | FANCB | 2187 | RNAseq | 1.3673 | 0.0647 | |
| SRP133303 | FANCB | 2187 | RNAseq | 1.7871 | 0.0004 | |
| SRP159526 | FANCB | 2187 | RNAseq | 1.6045 | 0.0015 | |
| SRP193095 | FANCB | 2187 | RNAseq | 0.9971 | 0.0000 | |
| TCGA | FANCB | 2187 | RNAseq | 1.4545 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by FANCB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FANCB:
No record found for this gene.
Somatic mutations of FANCB:
Generating mutation plots.
Highly correlated genes for FANCB:
Showing top 20/1418 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FANCB | MMS22L | 0.827104 | 3 | 0 | 3 |
| FANCB | ETV4 | 0.78297 | 4 | 0 | 4 |
| FANCB | PRKDC | 0.779127 | 5 | 0 | 5 |
| FANCB | KNTC1 | 0.77559 | 6 | 0 | 6 |
| FANCB | UCK2 | 0.774523 | 3 | 0 | 3 |
| FANCB | ZIC5 | 0.774488 | 3 | 0 | 3 |
| FANCB | DNMT1 | 0.76656 | 6 | 0 | 6 |
| FANCB | MMP12 | 0.762963 | 5 | 0 | 5 |
| FANCB | PYCR2 | 0.757269 | 3 | 0 | 3 |
| FANCB | MCM6 | 0.754296 | 6 | 0 | 6 |
| FANCB | SLC19A1 | 0.75236 | 3 | 0 | 3 |
| FANCB | GFM1 | 0.749702 | 4 | 0 | 4 |
| FANCB | DKC1 | 0.748726 | 3 | 0 | 3 |
| FANCB | FANCI | 0.748158 | 6 | 0 | 6 |
| FANCB | SNAP47 | 0.745925 | 3 | 0 | 3 |
| FANCB | WDR54 | 0.742968 | 5 | 0 | 5 |
| FANCB | SLC39A10 | 0.742843 | 4 | 0 | 4 |
| FANCB | MARCKSL1 | 0.741153 | 5 | 0 | 5 |
| FANCB | LAPTM4B | 0.740159 | 5 | 0 | 5 |
| FANCB | CXCL5 | 0.733711 | 3 | 0 | 3 |
For details and further investigation, click here
