| Full name: basic transcription factor 3 | Alias Symbol: BTF3a|BTF3b | ||
| Type: protein-coding gene | Cytoband: 5q13.2 | ||
| Entrez ID: 689 | HGNC ID: HGNC:1125 | Ensembl Gene: ENSG00000145741 | OMIM ID: 602542 |
Screen Evidence:
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Expression of BTF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BTF3 | 689 | 208517_x_at | -0.4986 | 0.0657 | |
| GSE20347 | BTF3 | 689 | 211939_x_at | -0.5528 | 0.0001 | |
| GSE23400 | BTF3 | 689 | 208517_x_at | -0.2548 | 0.0002 | |
| GSE26886 | BTF3 | 689 | 208517_x_at | -0.6759 | 0.0062 | |
| GSE29001 | BTF3 | 689 | 211939_x_at | -0.6923 | 0.1608 | |
| GSE38129 | BTF3 | 689 | 211939_x_at | -0.3716 | 0.0005 | |
| GSE45670 | BTF3 | 689 | 211939_x_at | -0.3205 | 0.0003 | |
| GSE53622 | BTF3 | 689 | 129646 | -0.4530 | 0.0000 | |
| GSE53624 | BTF3 | 689 | 129646 | -0.3445 | 0.0000 | |
| GSE63941 | BTF3 | 689 | 211939_x_at | 0.5616 | 0.0498 | |
| GSE77861 | BTF3 | 689 | 211939_x_at | -0.4576 | 0.0789 | |
| GSE97050 | BTF3 | 689 | A_24_P183264 | -0.0421 | 0.8864 | |
| SRP007169 | BTF3 | 689 | RNAseq | -1.1565 | 0.0108 | |
| SRP008496 | BTF3 | 689 | RNAseq | -1.2909 | 0.0000 | |
| SRP064894 | BTF3 | 689 | RNAseq | -0.7734 | 0.0003 | |
| SRP133303 | BTF3 | 689 | RNAseq | -0.6645 | 0.0000 | |
| SRP159526 | BTF3 | 689 | RNAseq | -0.7399 | 0.0378 | |
| SRP193095 | BTF3 | 689 | RNAseq | -1.1354 | 0.0000 | |
| SRP219564 | BTF3 | 689 | RNAseq | -0.8062 | 0.0001 | |
| TCGA | BTF3 | 689 | RNAseq | -0.0078 | 0.8652 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by BTF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BTF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BTF3 | 689 | 1 | 13 | 16 | |
| GSE20123 | BTF3 | 689 | 1 | 13 | 16 | |
| GSE43470 | BTF3 | 689 | 1 | 13 | 29 | |
| GSE46452 | BTF3 | 689 | 0 | 28 | 31 | |
| GSE47630 | BTF3 | 689 | 1 | 19 | 20 | |
| GSE54993 | BTF3 | 689 | 8 | 1 | 61 | |
| GSE54994 | BTF3 | 689 | 1 | 19 | 33 | |
| GSE60625 | BTF3 | 689 | 0 | 0 | 11 | |
| GSE74703 | BTF3 | 689 | 1 | 9 | 26 | |
| GSE74704 | BTF3 | 689 | 1 | 6 | 13 | |
| TCGA | BTF3 | 689 | 4 | 51 | 41 |
Total number of gains: 19; Total number of losses: 172; Total Number of normals: 297.
Somatic mutations of BTF3:
Generating mutation plots.
Highly correlated genes for BTF3:
Showing top 20/1034 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BTF3 | MOB3B | 0.791236 | 3 | 0 | 3 |
| BTF3 | ZCCHC9 | 0.750324 | 6 | 0 | 5 |
| BTF3 | ARPC1A | 0.749388 | 3 | 0 | 3 |
| BTF3 | NSA2 | 0.723724 | 13 | 0 | 12 |
| BTF3 | MRPS27 | 0.718231 | 13 | 0 | 11 |
| BTF3 | COG3 | 0.717188 | 3 | 0 | 3 |
| BTF3 | RSRC2 | 0.712957 | 3 | 0 | 3 |
| BTF3 | RPL29 | 0.711939 | 11 | 0 | 10 |
| BTF3 | POLK | 0.711671 | 4 | 0 | 3 |
| BTF3 | RAB18 | 0.70859 | 6 | 0 | 5 |
| BTF3 | DPY30 | 0.696832 | 3 | 0 | 3 |
| BTF3 | FAM174A | 0.691689 | 8 | 0 | 7 |
| BTF3 | AP3B1 | 0.689514 | 12 | 0 | 10 |
| BTF3 | EIF3I | 0.689046 | 4 | 0 | 4 |
| BTF3 | ITPRIP | 0.682939 | 3 | 0 | 3 |
| BTF3 | TVP23B | 0.682838 | 3 | 0 | 3 |
| BTF3 | SNX12 | 0.679455 | 4 | 0 | 3 |
| BTF3 | TMEM50A | 0.676457 | 4 | 0 | 3 |
| BTF3 | TMEM167A | 0.675744 | 4 | 0 | 4 |
| BTF3 | BHLHE40 | 0.675199 | 6 | 0 | 5 |
For details and further investigation, click here
