| Full name: eukaryotic translation initiation factor 3 subunit I | Alias Symbol: TRIP-1|eIF3-beta|eIF3-p36|eIF3i | ||
| Type: protein-coding gene | Cytoband: 1p35.2 | ||
| Entrez ID: 8668 | HGNC ID: HGNC:3272 | Ensembl Gene: ENSG00000084623 | OMIM ID: 603911 |
| Drug and gene relationship at DGIdb | |||
Expression of EIF3I:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF3I | 8668 | 208756_at | -0.0667 | 0.9069 | |
| GSE20347 | EIF3I | 8668 | 208756_at | -0.1585 | 0.3124 | |
| GSE23400 | EIF3I | 8668 | 208756_at | 0.1663 | 0.0036 | |
| GSE26886 | EIF3I | 8668 | 208756_at | -0.6267 | 0.0010 | |
| GSE29001 | EIF3I | 8668 | 208756_at | -0.3158 | 0.5064 | |
| GSE38129 | EIF3I | 8668 | 208756_at | 0.0029 | 0.9856 | |
| GSE45670 | EIF3I | 8668 | 208756_at | 0.0694 | 0.6320 | |
| GSE53622 | EIF3I | 8668 | 94214 | 0.2410 | 0.0000 | |
| GSE53624 | EIF3I | 8668 | 94214 | 0.2210 | 0.0001 | |
| GSE63941 | EIF3I | 8668 | 208756_at | 0.1336 | 0.7019 | |
| GSE77861 | EIF3I | 8668 | 208756_at | -0.0244 | 0.9392 | |
| GSE97050 | EIF3I | 8668 | A_23_P85560 | 0.5195 | 0.1377 | |
| SRP007169 | EIF3I | 8668 | RNAseq | -0.7486 | 0.0154 | |
| SRP008496 | EIF3I | 8668 | RNAseq | -0.8697 | 0.0000 | |
| SRP064894 | EIF3I | 8668 | RNAseq | 0.1539 | 0.4152 | |
| SRP133303 | EIF3I | 8668 | RNAseq | 0.1978 | 0.1300 | |
| SRP159526 | EIF3I | 8668 | RNAseq | -0.0720 | 0.7355 | |
| SRP193095 | EIF3I | 8668 | RNAseq | -0.2430 | 0.0442 | |
| SRP219564 | EIF3I | 8668 | RNAseq | -0.2653 | 0.2058 | |
| TCGA | EIF3I | 8668 | RNAseq | 0.0886 | 0.0458 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EIF3I expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF3I:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF3I | 8668 | 1 | 5 | 24 | |
| GSE20123 | EIF3I | 8668 | 1 | 4 | 25 | |
| GSE43470 | EIF3I | 8668 | 6 | 4 | 33 | |
| GSE46452 | EIF3I | 8668 | 5 | 1 | 53 | |
| GSE47630 | EIF3I | 8668 | 8 | 3 | 29 | |
| GSE54993 | EIF3I | 8668 | 1 | 1 | 68 | |
| GSE54994 | EIF3I | 8668 | 11 | 2 | 40 | |
| GSE60625 | EIF3I | 8668 | 0 | 0 | 11 | |
| GSE74703 | EIF3I | 8668 | 4 | 3 | 29 | |
| GSE74704 | EIF3I | 8668 | 0 | 0 | 20 | |
| TCGA | EIF3I | 8668 | 10 | 20 | 66 |
Total number of gains: 47; Total number of losses: 43; Total Number of normals: 398.
Somatic mutations of EIF3I:
Generating mutation plots.
Highly correlated genes for EIF3I:
Showing top 20/681 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF3I | NDUFS1 | 0.805088 | 3 | 0 | 3 |
| EIF3I | LYSMD3 | 0.775685 | 3 | 0 | 3 |
| EIF3I | RBM7 | 0.767658 | 3 | 0 | 3 |
| EIF3I | ZCCHC9 | 0.765288 | 3 | 0 | 3 |
| EIF3I | MRPL30 | 0.764506 | 3 | 0 | 3 |
| EIF3I | CASP4 | 0.763496 | 4 | 0 | 3 |
| EIF3I | RNF111 | 0.758334 | 3 | 0 | 3 |
| EIF3I | DUSP18 | 0.758205 | 3 | 0 | 3 |
| EIF3I | UBE3C | 0.754624 | 3 | 0 | 3 |
| EIF3I | FAM174A | 0.751119 | 3 | 0 | 3 |
| EIF3I | CTCF | 0.748911 | 3 | 0 | 3 |
| EIF3I | RAB21 | 0.745266 | 3 | 0 | 3 |
| EIF3I | SLC30A5 | 0.742822 | 4 | 0 | 4 |
| EIF3I | THAP2 | 0.741485 | 3 | 0 | 3 |
| EIF3I | LEPROT | 0.738321 | 4 | 0 | 4 |
| EIF3I | TRIM61 | 0.736511 | 3 | 0 | 3 |
| EIF3I | RNF181 | 0.734591 | 4 | 0 | 4 |
| EIF3I | DLD | 0.731003 | 3 | 0 | 3 |
| EIF3I | TTC37 | 0.730106 | 3 | 0 | 3 |
| EIF3I | SIAE | 0.726673 | 3 | 0 | 3 |
For details and further investigation, click here
