| Full name: family with sequence similarity 174 member A | Alias Symbol: UNQ1912|NS5ATP6 | ||
| Type: protein-coding gene | Cytoband: 5q21.1 | ||
| Entrez ID: 345757 | HGNC ID: HGNC:24943 | Ensembl Gene: ENSG00000174132 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM174A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM174A | 345757 | 226752_at | -0.7841 | 0.2333 | |
| GSE26886 | FAM174A | 345757 | 226752_at | -1.2264 | 0.0001 | |
| GSE45670 | FAM174A | 345757 | 226752_at | -0.4512 | 0.0217 | |
| GSE53622 | FAM174A | 345757 | 10904 | -1.1274 | 0.0000 | |
| GSE53624 | FAM174A | 345757 | 10904 | -0.9757 | 0.0000 | |
| GSE63941 | FAM174A | 345757 | 226752_at | -1.3773 | 0.1868 | |
| GSE77861 | FAM174A | 345757 | 226752_at | -1.0792 | 0.0019 | |
| GSE97050 | FAM174A | 345757 | A_23_P30283 | -0.5433 | 0.1453 | |
| SRP007169 | FAM174A | 345757 | RNAseq | -1.9193 | 0.0002 | |
| SRP008496 | FAM174A | 345757 | RNAseq | -1.4929 | 0.0000 | |
| SRP064894 | FAM174A | 345757 | RNAseq | -0.6026 | 0.0000 | |
| SRP133303 | FAM174A | 345757 | RNAseq | -0.0903 | 0.6785 | |
| SRP159526 | FAM174A | 345757 | RNAseq | -0.5868 | 0.1764 | |
| SRP193095 | FAM174A | 345757 | RNAseq | -0.9310 | 0.0000 | |
| SRP219564 | FAM174A | 345757 | RNAseq | -0.9636 | 0.0010 | |
| TCGA | FAM174A | 345757 | RNAseq | -0.1398 | 0.0794 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by FAM174A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM174A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM174A | 345757 | 1 | 13 | 16 | |
| GSE20123 | FAM174A | 345757 | 1 | 13 | 16 | |
| GSE43470 | FAM174A | 345757 | 2 | 9 | 32 | |
| GSE46452 | FAM174A | 345757 | 0 | 28 | 31 | |
| GSE47630 | FAM174A | 345757 | 0 | 20 | 20 | |
| GSE54993 | FAM174A | 345757 | 8 | 1 | 61 | |
| GSE54994 | FAM174A | 345757 | 1 | 18 | 34 | |
| GSE60625 | FAM174A | 345757 | 0 | 0 | 11 | |
| GSE74703 | FAM174A | 345757 | 1 | 7 | 28 | |
| GSE74704 | FAM174A | 345757 | 1 | 7 | 12 | |
| TCGA | FAM174A | 345757 | 3 | 43 | 50 |
Total number of gains: 18; Total number of losses: 159; Total Number of normals: 311.
Somatic mutations of FAM174A:
Generating mutation plots.
Highly correlated genes for FAM174A:
Showing top 20/1543 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM174A | GOLGA4 | 0.793972 | 5 | 0 | 5 |
| FAM174A | NDUFA13 | 0.785927 | 3 | 0 | 3 |
| FAM174A | FCHO2 | 0.784541 | 7 | 0 | 7 |
| FAM174A | MRPS36 | 0.784012 | 7 | 0 | 7 |
| FAM174A | YTHDF2 | 0.782738 | 3 | 0 | 3 |
| FAM174A | APPBP2 | 0.778879 | 3 | 0 | 3 |
| FAM174A | DUSP22 | 0.775387 | 6 | 0 | 6 |
| FAM174A | HERPUD2 | 0.775262 | 3 | 0 | 3 |
| FAM174A | COBLL1 | 0.77337 | 7 | 0 | 7 |
| FAM174A | GPD1L | 0.771906 | 6 | 0 | 6 |
| FAM174A | PITHD1 | 0.770184 | 6 | 0 | 6 |
| FAM174A | CCNYL1 | 0.766913 | 5 | 0 | 5 |
| FAM174A | IMPACT | 0.76135 | 3 | 0 | 3 |
| FAM174A | ZNF175 | 0.759284 | 3 | 0 | 3 |
| FAM174A | CPPED1 | 0.759193 | 7 | 0 | 7 |
| FAM174A | ZNF416 | 0.758742 | 4 | 0 | 4 |
| FAM174A | TMEM40 | 0.756424 | 6 | 0 | 6 |
| FAM174A | CCDC6 | 0.755437 | 6 | 0 | 5 |
| FAM174A | HPGD | 0.755393 | 6 | 0 | 6 |
| FAM174A | HSD17B4 | 0.752698 | 8 | 0 | 8 |
For details and further investigation, click here
