| Full name: mitochondrial ribosomal protein S27 | Alias Symbol: KIAA0264 | ||
| Type: protein-coding gene | Cytoband: 5q13.2 | ||
| Entrez ID: 23107 | HGNC ID: HGNC:14512 | Ensembl Gene: ENSG00000113048 | OMIM ID: 611989 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPS27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS27 | 23107 | 212145_at | -0.2391 | 0.5904 | |
| GSE20347 | MRPS27 | 23107 | 212145_at | -0.4051 | 0.0072 | |
| GSE23400 | MRPS27 | 23107 | 212145_at | 0.0323 | 0.6367 | |
| GSE26886 | MRPS27 | 23107 | 212145_at | -0.2770 | 0.1251 | |
| GSE29001 | MRPS27 | 23107 | 212145_at | -0.1418 | 0.4746 | |
| GSE38129 | MRPS27 | 23107 | 212145_at | -0.2604 | 0.0274 | |
| GSE45670 | MRPS27 | 23107 | 212145_at | -0.2859 | 0.0119 | |
| GSE53622 | MRPS27 | 23107 | 97403 | -0.2966 | 0.0000 | |
| GSE53624 | MRPS27 | 23107 | 97403 | -0.2108 | 0.0022 | |
| GSE63941 | MRPS27 | 23107 | 212145_at | 0.6250 | 0.1504 | |
| GSE77861 | MRPS27 | 23107 | 212145_at | -0.5399 | 0.0535 | |
| GSE97050 | MRPS27 | 23107 | A_23_P133332 | 0.1551 | 0.5185 | |
| SRP007169 | MRPS27 | 23107 | RNAseq | -0.3528 | 0.4316 | |
| SRP008496 | MRPS27 | 23107 | RNAseq | -0.6115 | 0.0397 | |
| SRP064894 | MRPS27 | 23107 | RNAseq | -0.2586 | 0.0316 | |
| SRP133303 | MRPS27 | 23107 | RNAseq | -0.2885 | 0.0034 | |
| SRP159526 | MRPS27 | 23107 | RNAseq | -0.3084 | 0.2894 | |
| SRP193095 | MRPS27 | 23107 | RNAseq | -0.4678 | 0.0000 | |
| SRP219564 | MRPS27 | 23107 | RNAseq | -0.4487 | 0.0740 | |
| TCGA | MRPS27 | 23107 | RNAseq | -0.0460 | 0.3411 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPS27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS27 | 23107 | 1 | 13 | 16 | |
| GSE20123 | MRPS27 | 23107 | 1 | 13 | 16 | |
| GSE43470 | MRPS27 | 23107 | 1 | 13 | 29 | |
| GSE46452 | MRPS27 | 23107 | 0 | 28 | 31 | |
| GSE47630 | MRPS27 | 23107 | 1 | 19 | 20 | |
| GSE54993 | MRPS27 | 23107 | 8 | 1 | 61 | |
| GSE54994 | MRPS27 | 23107 | 1 | 19 | 33 | |
| GSE60625 | MRPS27 | 23107 | 0 | 0 | 11 | |
| GSE74703 | MRPS27 | 23107 | 1 | 9 | 26 | |
| GSE74704 | MRPS27 | 23107 | 1 | 6 | 13 | |
| TCGA | MRPS27 | 23107 | 4 | 51 | 41 |
Total number of gains: 19; Total number of losses: 172; Total Number of normals: 297.
Somatic mutations of MRPS27:
Generating mutation plots.
Highly correlated genes for MRPS27:
Showing top 20/625 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS27 | BDP1 | 0.774072 | 4 | 0 | 4 |
| MRPS27 | SPTLC3 | 0.76449 | 3 | 0 | 3 |
| MRPS27 | SLC10A7 | 0.762475 | 3 | 0 | 3 |
| MRPS27 | CHRNB1 | 0.757534 | 3 | 0 | 3 |
| MRPS27 | GFM2 | 0.747168 | 4 | 0 | 4 |
| MRPS27 | PDZD11 | 0.735059 | 3 | 0 | 3 |
| MRPS27 | ETS2 | 0.728547 | 3 | 0 | 3 |
| MRPS27 | ATF1 | 0.727732 | 3 | 0 | 3 |
| MRPS27 | CYB5B | 0.726533 | 3 | 0 | 3 |
| MRPS27 | LEPROT | 0.722076 | 4 | 0 | 3 |
| MRPS27 | ANKRD13C | 0.719282 | 3 | 0 | 3 |
| MRPS27 | BTF3 | 0.718231 | 13 | 0 | 11 |
| MRPS27 | SDHB | 0.715968 | 4 | 0 | 4 |
| MRPS27 | MRPL44 | 0.707196 | 5 | 0 | 5 |
| MRPS27 | NSRP1 | 0.704513 | 3 | 0 | 3 |
| MRPS27 | DHRS7 | 0.698959 | 5 | 0 | 4 |
| MRPS27 | CTBS | 0.695367 | 5 | 0 | 4 |
| MRPS27 | TRIM61 | 0.694009 | 4 | 0 | 3 |
| MRPS27 | THAP2 | 0.691244 | 5 | 0 | 5 |
| MRPS27 | ATL2 | 0.685234 | 3 | 0 | 3 |
For details and further investigation, click here
